The prize-winning and best-selling author of Say Nothing presents a grand, devastating portrait of three generations of the Sackler family, famed for their philanthropy, whose fortune was built by Valium and whose reputation was destroyed by OxyContin. Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling.

A silent epidemic of chronic illnesses afflicts tens of millions of Americans: These are diseases that are poorly understood, frequently marginalized, and can go undiagnosed and unrecognized altogether. Renowned writer Meghan O’Rourke delivers a revelatory investigation into this elusive category of “invisible” illness that encompasses autoimmune diseases, post-treatment Lyme disease syndrome, and now long COVID, synthesizing the personal and the universal to help all of us through this new frontier.

An astonishing new science called neuroplasticity is overthrowing the centuries-old notion that the human brain is immutable. Psychiatrist and psychoanalyst, Norman Doidge, MD, traveled the country to meet both the brilliant scientists championing neuroplasticity and the people whose lives they've transformed - people whose mental limitations or brain damage were seen as unalterable.

You are not doomed by your genes and hardwired to be a certain way for the rest of your life. A new science is emerging that empowers all human beings to create the reality they choose. In Breaking the Habit of Being Yourself, renowned author, speaker, researcher, and chiropractor Dr. Joe Dispenza combines the fields of quantum physics, neuroscience, brain chemistry, biology, and genetics to show you what is truly possible.

In 1978 Susan Sontag wrote Illness as Metaphor, a classic work described by Newsweek as “one of the most liberating books of its time”. A cancer patient herself when she was writing the book, Sontag shows how the metaphors and myths surrounding certain illnesses, especially cancer, add greatly to the suffering of patients and often inhibit them from seeking proper treatment.

Blue Dreams offers the explosive story of the discovery, invention, people, and science behind our licensed narcotics, as told by a riveting writer and psychologist who shares her own intimate experience with the highs and lows of psychiatry's drugs. Lauren Slater's account ranges from the earliest, Thorazine and lithium, up through Prozac and other antidepressants, as well as Ecstasy, "magic mushrooms", the most cutting-edge memory drugs, and even neural implants.

Trauma is a fact of life. Veterans and their families deal with the painful aftermath of combat; one in five Americans has been molested; one in four grew up with alcoholics; one in three couples have engaged in physical violence. Dr. Bessel van der Kolk, one of the world’s foremost experts on trauma, has spent more than three decades working with survivors. In The Body Keeps the Score, he uses recent scientific advances to show how trauma literally reshapes both body and brain, compromising sufferers’ capacities for pleasure, engagement, self-control, and trust.

When Michael Pollan set out to research how LSD and psilocybin (the active ingredient in magic mushrooms) are being used to provide relief to people suffering from difficult-to-treat conditions such as depression, addiction, and anxiety, he did not intend to write what is undoubtedly his most personal book. But upon discovering how these remarkable substances are improving the lives not only of the mentally ill but also of healthy people coming to grips with the challenges of everyday life, he decided to explore the landscape of the mind in the first person as well as the third.

Decades before the American Revolution, Benjamin Franklin lamented that English settlers were constantly fleeing over to the Indians - but Indians almost never did the same. Tribal society has been exerting an almost gravitational pull on Westerners for hundreds of years, and the reason lies deep in our evolutionary past as a communal species. The most recent example of that attraction is combat veterans who come home to find themselves missing the incredibly intimate bonds of platoon life.

In The Brain That Changes Itself, Norman Doidge described the most important breakthrough in our understanding of the brain in 400 years: the discovery that the brain can change its own structure and function in response to mental experience - what we call neuroplasticity. His revolutionary new book shows, for the first time, how the amazing process of neuroplastic healing really works. It describes natural, noninvasive avenues into the brain provided by the forms of energy around us.

From the New York Times best-selling author of Chasing the Scream, a radically new way of thinking about depression and anxiety. What really causes depression and anxiety - and how can we really solve them?

A groundbreaking book about personal growth that presents a uniquely effective set of five tools that bring about dynamic change. The Tools offers a solution to the biggest complaint patients have about therapy: the interminable wait for change to begin. The traditional therapeutic model sets its sights on the past, but Phil Stutz and Barry Michels employ an arsenal of techniques - "the tools" - that allow patients to use their problems as levers that access the power of the unconscious and propel them into action.

Dr. Jamison is one of the foremost authorities on manic-depressive (bipolar) illness; she has also experienced it firsthand. For even while she was pursuing her career in academic medicine, Jamison found herself succumbing to the same exhilarating highs and catastrophic depressions that afflicted many of her patients, as her disorder launched her into ruinous spending sprees, episodes of violence, and an attempted suicide.

Dr. John E. Sarno's Healing Back Pain is a New York Times best seller that has helped over 500,000 readers. Continuing the research since his ground-breaking book, the renowned physician now presents his most complete work yet on the vital connection between mental and bodily health.... Musculoskeletal pain disorders have reached epidemic proportions in the United States, with most doctors failing to recognize their underlying cause.

With case histories and the results of in-depth mind-body research, Dr. Sarno describes how patients recognize the emotional roots of their back pain and sever the connections between mental and physical pain - and how, just by listening to this program, you may start recovering from back pain today!

Falling into the Fire is psychiatrist Christine Montross's thoughtful investigation of the gripping patient encounters that have challenged and deepened her practice. Beautifully written, deeply felt, Falling into the Fire brings us inside the doctor’s mind, illuminating the grave human costs of mental illness as well as the challenges of diagnosis and treatment. At once rigorous and meditative, Falling into the Fire is an intimate portrait of psychiatry, allowing the reader to witness the humanity of the practice and the enduring mysteries of the mind.

With case histories and the results of in-depth mind-body research, Dr. Sarno describes how patients recognize the emotional roots of their back pain and sever the connections between mental and physical pain - and how, just by listening to this program, you may start recovering from back pain today!

Am I happy enough? This has been a pivotal question since America's inception. "Am I not happy enough because I am depressed?" is a more recent version. Psychotherapist Gary Greenberg shows how depression has been manufactured---not as an illness but as an idea about our suffering, its source, and its relief. He challenges us to look at depression in a new way.

Published in partnership with the International Association for the Study of Pain, A Nation in Pain offers a sweeping, deeply researched account of the chronic pain crisis, from neurobiology to public policy, and presents practical solutions that are within our grasp today. Drawing on both her personal experience with chronic pain and her background as an award-winning health journalist, she guides us through recent scientific discoveries, including genetic susceptibility to pain.

An astonishing new science called neuroplasticity is overthrowing the centuries-old notion that the human brain is immutable. Psychiatrist and psychoanalyst, Norman Doidge, MD, traveled the country to meet both the brilliant scientists championing neuroplasticity and the people whose lives they've transformed - people whose mental limitations or brain damage were seen as unalterable.

Drawing on 40 years of research and patient care, Dr. Wayne Jonas explains how 80 percent of healing occurs organically and how to activate the healing process. In How Healing Works, Dr. Wayne Jonas lays out a revolutionary new way to approach injury, illness, and wellness. Dr. Jonas explains the biology of healing and the science behind the discovery that 80 percent of healing can be attributed to the mind-body connection and other naturally occurring processes. Jonas details how the healing process works and what we can do to facilitate our own innate ability to heal.

Trauma is a fact of life. Veterans and their families deal with the painful aftermath of combat; one in five Americans has been molested; one in four grew up with alcoholics; one in three couples have engaged in physical violence. Dr. Bessel van der Kolk, one of the world’s foremost experts on trauma, has spent more than three decades working with survivors. In The Body Keeps the Score, he uses recent scientific advances to show how trauma literally reshapes both body and brain, compromising sufferers’ capacities for pleasure, engagement, self-control, and trust.

On average, a physician will interrupt a patient describing her symptoms within 12 seconds. In that short time, many doctors decide on the likely diagnosis and best treatment. Often, decisions made this way are correct, but at crucial moments they can also be wrong: with catastrophic consequences. In this myth-shattering book, Jerome Groopman pinpoints the forces and thought processes behind the decisions doctors make.

Important and provocative, The Undead examines why even with the tools of advanced technology, what we think of as life and death, consciousness and nonconsciousness, is not exactly clear - and how this problem has been further complicated by the business of organ harvesting.

The first comprehensive look at the groundbreaking field of energy medicine and how it can be used to diagnose and treat illness, from one of the world’s foremost practitioners of traditional Chinese medicine.

For centuries, the human heart seemed beyond our understanding: an inscrutable shuddering mass that was somehow the driver of emotion and the seat of the soul. As cardiologist and best-selling author Sandeep Jauhar tells in The Heart, it was only recently that we demolished age-old taboos and devised the transformative procedures that changed the way we live. Deftly alternating between historical episodes and his own work, Jauhar tells the colorful and little known story of the doctors who risked their careers and the patients who risked their lives to know and heal our most vital organ.

Mr. A. was admitted to Dr. Joel Gold’s inpatient unit at Bellevue Hospital in 2002. He was, he said, being filmed constantly, and his life was being broadcast around the world "like The Truman Show" - the 1998 film depicting a man who is unknowingly living out his life as the star of a popular soap opera. Over the next few years, Gold saw a number of patients suffering from what he and his brother, Dr. Ian Gold, began calling the "Truman Show Delusion," launching them on a quest to understand the nature of this particular phenomenon and the nature of madness itself.

If we could turn back the clock psychologically, could we also turn it back physically? For more than 30 years, award-winning social psychologist Ellen Langer has studied this provocative question, and now has a conclusive answer: opening our minds to what's possible, instead of clinging to accepted notions about what's not, can lead to better health at any age.

America has been the world leader in generating new mental health treatments and modern theories of the human psyche. We export our psychopharmaceuticals packaged with the certainty that our biomedical knowledge will relieve the suffering and stigma of mental illness. We categorize disorders, thereby defining mental illness and health, and then parade these seemingly scientific certainties in front of the world.

From the best-selling author of Gratitude and On the Move, a final volume of essays that showcase Sacks's broad range of interests - from his passion for ferns, swimming, and horsetails, to his final case histories exploring schizophrenia, dementia, and Alzheimer's.