When 24-year-old Susannah Cahalan woke up alone in a hospital room, strapped to her bed and unable to move or speak, she had no memory of how she’d gotten there. Days earlier, she had been on the threshold of a new, adult life: At the beginning of her first serious relationship and a promising career at a major New York newspaper. Now she was labeled violent, psychotic, a flight risk. What happened?

In the 1980s, American psychiatry announced that it was time to toss aside Freudian ideas of mental disorder because the true path to understanding and treating mental illness lay in brain science, biochemistry, and drugs. This sudden call to revolution, however, was not driven by any scientific breakthroughs. Nor was it as unprecedented as it seemed. Why had previous efforts stalled? Was this latest call really any different? In Mind Fixers, Anne Harrington offers the first comprehensive history of the troubled search for the biological basis of mental illness.

Don and Mimi Galvin seemed to be living the American dream. After World War II, Don's work with the Air Force brought them to Colorado, where their 12 children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years, there was an established script for a family like the Galvins—aspiration, hard work, upward mobility, domestic harmony. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse. By the mid-1970s, six of the 10 Galvin boys, one after another, were diagnosed as schizophrenic.

On the night of her high school graduation, a young woman follows her older sister Debbie to Salvation, a Los Angeles bar patronized by energy healers, aspiring actors, and all-around misfits. After the two share a bag of unidentified pills, the evening turns into a haze of sensual and risky interactions—nothing unusual for two sisters bound in an incredibly toxic relationship. Our unnamed narrator has always been under the spell of the alluring and rebellious Debbie and, despite her own hesitations, she has always said yes to nights like these. That is, until Debbie disappears.

In 1954, researchers at the newly formed National Institute of Mental Health set out to study the genetics of schizophrenia. When they got word that four 24-year-old identical quadruplets in Lansing, Michigan, had all been diagnosed with the mental illness, they could hardly believe their ears. Here was incontrovertible proof of hereditary transmission and, thus, a chance to bring international fame to their fledgling institution.

Moving, harrowing, and ultimately uplifting, Lori Schiller's memoir is a classic testimony to the ravages of mental illness and the power of perseverance and courage. At 17, Lori Schiller was the perfect child - the only daughter of an affluent, close-knit family. Six years later she made her first suicide attempt, then wandered the streets of New York City dressed in ragged clothes, tormenting voices crying out in her mind. Lori Schiller had entered the horrifying world of full-blown schizophrenia.

An intimate, moving book written with the immediacy and directness of one who still struggles with the effects of mental and chronic illness, The Collected Schizophrenias cuts right to the core. Schizophrenia is not a single unifying diagnosis, and Esmé Weijun Wang writes not just to her fellow members of the “collected schizophrenias” but to those who wish to understand it as well.

For more than two hundred years, disturbances of the mind—the sorts of things that were once called "madness"—have been studied and treated by the medical profession. Mental illness, some insist, is a disease like any other, whose origins can be identified and from which one can be cured. But is this true? In this masterful account of America's quest to understand and treat everything from anxiety to psychosis, one of the most provocative thinkers writing about psychiatry today sheds light on its tumultuous past.

In her early 20s, investigative journalist Anna Mehler Paperny had already landed her dream job. On the surface, her life was great. Nevertheless, she spiraled out, attempted suicide (the first of more attempts to follow), and landed in the ICU and then in a psych ward before setting out to tackle her recovery. In Hello I Want to Die Please Fix Me, Mehler Paperny turns her journalist's eye on her own experience and others' - in the ward; as an outpatient; facing family, friends, and coworkers; finding the right meds; trying to stay insured and employed.

Asylums are supposed to be in the past. However, though the buildings were closed, many of the practices lived on. In fact, more law-abiding Americans today are being involuntarily committed and forcibly treated "for their own good" than at any time in history.

Professor of psychiatry Elyn R. Saks writes about her struggle with schizophrenia in this unflinching account of her mental illness. In The Center Cannot Hold, Saks draws readers into a nightmare world of medications, a misguided health-care system, and social stigmas. But she would not be defeated. With a strength and force of will that most can only imagine, Saks reclaimed her life and went on to achieve great success.

In 1953, a 27-year-old factory worker named Henry Molaison - who suffered from severe epilepsy - received a radical new version of the then-common lobotomy, targeting the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry was left profoundly amnesic, unable to create long-term memories. Over the next 60 years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.

When Michael Pollan set out to research how LSD and psilocybin (the active ingredient in magic mushrooms) are being used to provide relief to people suffering from difficult-to-treat conditions such as depression, addiction, and anxiety, he did not intend to write what is undoubtedly his most personal book. But upon discovering how these remarkable substances are improving the lives not only of the mentally ill but also of healthy people coming to grips with the challenges of everyday life, he decided to explore the landscape of the mind in the first person as well as the third.

We know of psychopaths from chilling headlines and stories in the news and movies - from Ted Bundy and John Wayne Gacy to Hannibal Lecter and Dexter Morgan. As Dr. Kent Kiehl shows, psychopaths can be identified by a checklist of symptoms that includes pathological lying; lack of empathy, guilt, and remorse; grandiose sense of self-worth; manipulation; and failure to accept one’s actions. But why do psychopaths behave the way they do? Is it the result of their environment - how they were raised - or is there a genetic component to their lack of conscience?

E. Fuller Torrey's audiobook provides an inside perspective on the birth of the federal mental health program. On staff at the National Institute of Mental Health when the program was being developed and implemented, Torrey draws on his own first-hand account of the creation and launch of the program, extensive research, one-on-one interviews with people involved, and recently unearthed audiotapes of interviews with major figures involved in the legislation. As such, this book provides historical material previously unavailable to the public.

America has been the world leader in generating new mental health treatments and modern theories of the human psyche. We export our psychopharmaceuticals packaged with the certainty that our biomedical knowledge will relieve the suffering and stigma of mental illness. We categorize disorders, thereby defining mental illness and health, and then parade these seemingly scientific certainties in front of the world.

Am I happy enough? This has been a pivotal question since America's inception. "Am I not happy enough because I am depressed?" is a more recent version. Psychotherapist Gary Greenberg shows how depression has been manufactured---not as an illness but as an idea about our suffering, its source, and its relief. He challenges us to look at depression in a new way.

In 2020, an estimated 5.8 million Americans had Alzheimer’s, and more than half a million died because of the disease and its devastating complications. Sixteen million caregivers are responsible for paying as much as half of the $226 billion annual costs of their care. As more people live beyond their 70s and 80s, the number of patients will rise to an estimated 13.8 million by 2025. Part case studies, part meditation on the past, present and future of the disease, The Problem of Alzheimer's traces Alzheimer’s from its beginnings to its recognition as a crisis.

Mr. A. was admitted to Dr. Joel Gold’s inpatient unit at Bellevue Hospital in 2002. He was, he said, being filmed constantly, and his life was being broadcast around the world "like The Truman Show" - the 1998 film depicting a man who is unknowingly living out his life as the star of a popular soap opera. Over the next few years, Gold saw a number of patients suffering from what he and his brother, Dr. Ian Gold, began calling the "Truman Show Delusion," launching them on a quest to understand the nature of this particular phenomenon and the nature of madness itself.

For more than two years, author and psychotherapist Gary Greenberg has embedded himself in the war that broke out over the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (the DSM) - the American Psychiatric Association's (APA) compendium of mental illnesses and what Greenberg calls "the book of woe". Since its debut in 1952, the book has been frequently revised, and with each revision, the "official" view on which psychological problems constitute mental illness has changed.

The grandfather of the NDE (near death experience) movement, Raymond Moody has, in the words of Dr. Larry Dossey, author of The Power of Premonitions, "radically changed the way modern humans think about the afterlife." Paranormal, essential listening for fans of Dannion Brinkley and Jeffrey Long, is "a thrilling and inspiring literary experience. Anyone who is not grateful for Moody's immense contribution to human welfare ought to check his pulse."

Journalist Debbie Nathan reveals the true story behind the famous case of Sybil, the woman with sixteen different personalities.

The psychiatric emergency room, a fast-paced combat zone with pressure to match, thrusts its medical providers into the outland of human experience where they must respond rapidly and decisively in spite of uncertainty and, very often, danger. In this lively first-person narrative, Paul R. Linde takes listeners behind the scenes at an urban psychiatric emergency room, with all its chaos and pathos, where we witness mental health professionals doing their best to alleviate suffering.

Falling into the Fire is psychiatrist Christine Montross's thoughtful investigation of the gripping patient encounters that have challenged and deepened her practice. Beautifully written, deeply felt, Falling into the Fire brings us inside the doctor’s mind, illuminating the grave human costs of mental illness as well as the challenges of diagnosis and treatment. At once rigorous and meditative, Falling into the Fire is an intimate portrait of psychiatry, allowing the reader to witness the humanity of the practice and the enduring mysteries of the mind.

More than four hundred abandoned suitcases filled with patients’ belongings were found when Willard Psychiatric Center closed in 1995 after 125 years of operation. They are skillfully examined here and compared to the written record to create a moving—and devastating—group portrait of twentieth-century American psychiatric care.

The noted research psychiatrist explores how life's disappointments and difficulties provide us with the lessons we need to become better, bigger, and more resilient human beings. Adversity is an irreducible fact of life. Although we can and should learn from all experiences, both positive and negative best-selling author Dr. Norman E. Rosenthal believes that adversity is by far the best teacher most of us will ever encounter.

In Saving Normal, Allen Frances, one of the world's most influential psychiatrists, warns that mislabeling everyday problems as mental illness has shocking implications for individuals and society: Stigmatizing a healthy person as mentally ill leads to unnecessary, harmful medications, the narrowing of horizons, misallocation of medical resources, and draining of the budgets of families and the nation.

When Damon Tweedy begins medical school, he envisions a bright future where his segregated, working-class background will become largely irrelevant. Instead, he finds that he has joined a new world where race is front and center. The recipient of a scholarship designed to increase black student enrollment, Tweedy soon meets a professor who bluntly questions whether he belongs in medical school, a moment that crystallizes the challenges he will face throughout his career.

Following the death of her father, journalist and hospice volunteer Ann Neumann sets out to examine what it means to die well in the United States. When Ann Neumann's father was diagnosed with non-Hodgkin's lymphoma, she left her job and moved back to her hometown of Lancaster, Pennsylvania. She became his full-time caregiver - cooking, cleaning, and administering medications. When her father died, she was undone by the experience, by grief and the visceral quality of dying.

A powerful defense of intellectual freedom told through the ordeals of contemporary scientists attacked for exploring controversial ideas, by a noted science historian and medical activist.

When 24-year-old Susannah Cahalan woke up alone in a hospital room, strapped to her bed and unable to move or speak, she had no memory of how she’d gotten there. Days earlier, she had been on the threshold of a new, adult life: At the beginning of her first serious relationship and a promising career at a major New York newspaper. Now she was labeled violent, psychotic, a flight risk. What happened?

In 1954, researchers at the newly formed National Institute of Mental Health set out to study the genetics of schizophrenia. When they got word that four 24-year-old identical quadruplets in Lansing, Michigan, had all been diagnosed with the mental illness, they could hardly believe their ears. Here was incontrovertible proof of hereditary transmission and, thus, a chance to bring international fame to their fledgling institution.

In 1953, a 27-year-old factory worker named Henry Molaison - who suffered from severe epilepsy - received a radical new version of the then-common lobotomy, targeting the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry was left profoundly amnesic, unable to create long-term memories. Over the next 60 years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.

Don and Mimi Galvin seemed to be living the American dream. After World War II, Don's work with the Air Force brought them to Colorado, where their 12 children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years, there was an established script for a family like the Galvins—aspiration, hard work, upward mobility, domestic harmony. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse. By the mid-1970s, six of the 10 Galvin boys, one after another, were diagnosed as schizophrenic.

Unconscious bias: persistent, unintentional prejudiced behavior that clashes with our consciously held beliefs. We know that it exists, to corrosive and even lethal effect. We see it in medicine, the workplace, education, policing, and beyond. But when it comes to uprooting our prejudices, we still have far to go. With nuance, compassion, and ten years' immersion in the topic, Jessica Nordell weaves gripping stories with scientific research to reveal how minds, hearts, and behaviors change.

From New York Times best-selling author and blogger Heather B. Armstrong comes an honest and irreverent memoir - reminiscent of the New York Times best-seller Brain on Fire - about her experience as one of only a few people to participate in an experimental treatment for depression involving 10 rounds of a chemically induced coma approximating brain death.

1860: As the clash between the states rolls slowly to a boil, Elizabeth Packard, housewife and mother of six, is facing her own battle. The enemy sits across the table and sleeps in the next room. Her husband of 21 years is plotting against her because he feels increasingly threatened - by Elizabeth’s intellect, independence, and unwillingness to stifle her own thoughts. So Theophilus makes a plan to put his wife back in her place. One summer morning, he has her committed to an insane asylum.

Growing up in the 1960s in the suburbs of Chicago, Meg Kissinger’s family seemed to live a charmed life. With eight kids and two loving parents, the Kissingers radiated a warm, boisterous energy. Whether they were spending summer days on the shores of Lake Michigan, barreling down the ski slopes, or navigating the trials of their Catholic school, the Kissingers always knew how to live large and play hard. But behind closed doors, a harsher reality was unfolding.

In her mid-20s, at the height of tech industry idealism, Anna Wiener - stuck, broke, and looking for meaning in her work, like any good millennial - left a job in book publishing for the promise of the new digital economy. She moved from New York to San Francisco, where she landed at a big-data startup in the heart of the Silicon Valley bubble: A world of surreal extravagance, dubious success, and fresh-faced entrepreneurs hell-bent on domination, glory, and, of course, progress.

In this close-up look at the ardent love affair between the author and her painting teacher, which began in the 1970s, when she was seventeen and he was forty-seven and married with two children, Ciment not only reflects on how their love ignited (who leaned in first for that kiss?) but interrogates her 1990s memoir on the subject, Half a Life. She asks herself if she told the whole truth when she wrote about their passion back then, and what truth looked like to her in the even longer-ago era of love-bead curtains when she fell in love.