For centuries, doctors have struggled to define mental illness - how do you diagnose it, how do you treat it, how do you even know what it is? In search of an answer, in the 1970s a Stanford psychologist named David Rosenhan and seven other people - sane, normal, well-adjusted members of society - went undercover into asylums around America to test the legitimacy of psychiatry's labels. Rosenhan's watershed study broke open the field of psychiatry, closing down institutions and changing mental health diagnosis forever.

Dr. Jamison is one of the foremost authorities on manic-depressive (bipolar) illness; she has also experienced it firsthand. For even while she was pursuing her career in academic medicine, Jamison found herself succumbing to the same exhilarating highs and catastrophic depressions that afflicted many of her patients, as her disorder launched her into ruinous spending sprees, episodes of violence, and an attempted suicide.

Professor of psychiatry Elyn R. Saks writes about her struggle with schizophrenia in this unflinching account of her mental illness. In The Center Cannot Hold, Saks draws readers into a nightmare world of medications, a misguided health-care system, and social stigmas. But she would not be defeated. With a strength and force of will that most can only imagine, Saks reclaimed her life and went on to achieve great success.

Oliver Sacks' The Man Who Mistook His Wife for a Hat tells the stories of individuals afflicted with fantastic perceptual and intellectual aberrations: patients who have lost their memories and with them the greater part of their pasts; who are no longer able to recognize people and common objects; who are stricken with violent tics and grimaces or who shout involuntary obscenities; whose limbs have become alien; who have been dismissed as retarded yet are gifted with uncanny artistic or mathematical talents.

In the summer of 1962, a young student named Joachim Rudolph dug a tunnel under the Berlin Wall. Waiting on the other side in East Berlin were dozens of men, women, and children - all willing to risk everything to escape.

Jamie Foxx has won an Academy Award and a Grammy Award, laughed with sitting presidents, and partied with the biggest names in hip-hop. In Act Like You Got Some Sense, Jamie shares up close and personal stories about the tough love and old-school values he learned growing up in the small town of Terrell, Texas; his early days trying to make it in Hollywood; the joys and challenges of achieving stardom; and how each phase of his life shaped his parenting journey. Hilarious, poignant, and always brutally honest, this is Jamie Foxx like we’ve never seen him before.

Harry Cliff - a University of Cambridge particle physicist and researcher on the Large Hadron Collider - sets out in pursuit of answers. He ventures to the largest underground research facility in the world, deep beneath Italy's Gran Sasso mountains, where scientists gaze into the heart of the Sun using the most elusive of particles, the ghostly neutrino. He visits CERN in Switzerland to explore the "Antimatter Factory," where the stuff of science fiction is manufactured daily (and we're close to knowing whether it falls up).

Back when restaurant menus were still printed on paper, and wearing a mask—or not—was a decision made mostly on Halloween, David Sedaris spent his time doing normal things. As Happy-Go-Lucky opens, he is learning to shoot guns with his sister, visiting muddy flea markets in Serbia, buying gummy worms to feed to ants, and telling his nonagenarian father wheelchair jokes. But then the pandemic hits, and like so many others, he’s stuck in lockdown, unable to tour and read for audiences, the part of his work he loves most.

From the guitarist of the pioneering band Sleater-Kinney, the book Kim Gordon says "everyone has been waiting for" and a New York Times Notable Book of 2015 - a candid, funny, and deeply personal look at making a life - and finding yourself - in music. Before Carrie Brownstein became a music icon, she was a young girl growing up in the Pacific Northwest just as it was becoming the setting for one the most important movements in rock history.

In this harrowing New York Times best seller, Ann Rule is at her masterful best as she winnows horrific truths from the ashes of what seemed like paradise in Prairie Village, Kansas. Rule probes the case of Debora Green, a doctor and a loving mother who seemed to epitomize the dreams of the American heartland. A small-town girl with a genius IQ, she achieved an enviable life. But when a raging fire destroyed that home and took two lives, the trail of clues led investigators to a stunning conclusion.

What happens when nothing happens? Maryanne wonders in A Year of Cats and Dogs, a darkly funny yet hopeful novel about a woman in mid-life who feels surrounded by death. She answers her own question by deciding to find out.

Although happily ensconced in a loving second marriage and a new family of quadruplets, Sheila Blackthorne Bellush never truly escaped the enslavement of her ex-husband, multimillionaire Allen Blackthorne, a handsome charmer - and a violent, controlling sociopath who terrorized her for a decade after their divorce. When Sheila was slain in her home, in the presence of her four toddlers, authorities raced to link the crime to Blackthorne, the man who vowed to monitor Sheila's every move in his obsessive quest for power and revenge.

Born to indigenous working-class Mexican immigrants in San Diego in the 1970s, Jesse Leon’s childhood was violently ruptured. A dangerous and harrowing encounter at a local gift shop when he was eleven years old left Jesse with a deadly secret. Hurt, alone, and scared for his life, Jesse numbed his pain by losing himself in the hyper-masculine culture of the streets and wherever else he could find it—in alcohol, drugs, and prostitution.

Oxygen takes the listener on an enthralling journey, as gripping as a thriller, as it unravels the unexpected ways in which oxygen spurred the evolution of life and death.

Twelve years ago Jessica Williams escaped a cult. Thanks to the private detective who rescued her, she reintegrated into society, endured an uncomfortable notoriety, and tried to put it all behind her. Then, at an airport bar, Jessica meets a woman with an identical name and birth date. It appears to be just an odd coincidence - until a week later, when Jessica finds her bank account drained and her personal information stolen. Following a trail of the grifter’s victims, each with the same name, Jessica gathers players - one by one - for her own game.

In 2015, Barbara Lipska - a leading expert on the neuroscience of mental illness - was diagnosed with melanoma that had spread to her brain. Within months, her frontal lobe, the seat of cognition, began shutting down. She descended into madness, exhibiting dementia- and schizophrenia-like symptoms that terrified her family and coworkers. But miraculously, the immunotherapy her doctors had prescribed worked quickly. Just eight weeks after her nightmare began, Lipska returned to normal. With one difference: she remembered her brush with madness with exquisite clarity.

True stories are more bizarre than any fiction, and Dr. Gary Small knows this best. After 30 distinguished years of psychiatry and groundbreaking research on the human brain, Dr. Small has seen it all - now he is ready to open his office doors for the first time and tell all about the most mysterious, intriguing, and bizarre patients of his career. The Naked Lady Who Stood on Her Head is a spellbinding record of the doctor's most bewildering cases.

Julia Fox Garrison refused to listen to the professionals she called Dr. Jerk and Dr. Panic, who - after she suffered a massive, debilitating stroke at age thirty-seven - told her she’d probably die, or to Nurse Doom, who ignored her emergency call button. Instead she heeded the advice of kind, gifted Dr. Neuro, who promised her he would “treat your mind as well as your body.” Julia figured if she could somehow manage to get herself into a wheelchair, at least she’d always find parking. But after many, many months of hospitalization and rehab, Julia not only got into a wheelchair, but she got back out.

Brainstorm follows the stories of people whose medical diagnoses are so strange even their doctor struggles to know how to solve them. A man who sees cartoon characters running across the room; a girl whose world suddenly seems completely distorted, as though she were Alice in Wonderland; another who transforms into a ragdoll whenever she even thinks about moving. The brain is the most complex structure in the universe. Neurologists must puzzle out life-changing diagnoses from the tiniest of clues, the ultimate medical detective work.

His name was Joshua Silver. He was 23 years old, educated, and had an impressive vocabulary. The NYPD had found Joshua Silver naked in Times Square, barking like a dog. It was just another night for Julie Holland, the attending doctor in the world famous Bellevue Hospital's psychiatric emergency room.

Lauren Marks was 27 when an aneurysm ruptured in her brain and left her fighting for her life. She woke up in a hospital soon after with serious deficiencies to her reading, speaking, and writing abilities, and an unfamiliar diagnosis: aphasia. This would be shocking news for anyone, but Lauren was a voracious reader, an actress, director, dramaturg, and pursuing her PhD. At any other period of her life, this diagnosis would have been a devastating blow. But she woke up...different.

Here, Michael Palmer has created a cat-and-mouse game where one woman must confront a conspiracy of doctors to uncover an evil practice that touches every single person who ever has a medical test. With unforgettable characters and twists and betrayals that come from the most unlikely places, The Second Opinion will keep you guessing...and looking over your shoulder.

From the moment Martha and her husband, John, conceived their second child, all hell broke loose. They were a couple obsessed with success. After years of matching IQs and test scores with less driven peers, they had two Harvard degrees apiece and were gunning for more. But the dream had begun to disintegrate. Then, when their unborn son, Adam, was diagnosed with Down syndrome, doctors, advisers, and friends in the Harvard community warned them not to keep the baby.

Nearly 26 years after receiving her first heart transplant, Amy Silverstein's donor heart plummeted into failure. If she wanted to live, she had to take on the grueling quest for a new heart - immediately. A shot at survival meant uprooting her life and moving across the country to California. When her friends heard of her plans, there was only one reaction: "I'm there." Nine remarkable women - Joy, Jill, Leja, Jody, Lauren, Robin, Valerie, Ann, and Jane - put demanding jobs and pressing family obligations on hold to fly across the country and be by Amy's side.

At the age of two, Carly Fleischmann was diagnosed with severe autism and an oral motor condition that prevented her from speaking. Doctors predicted that she would never intellectually develop beyond the abilities of a small child. Although she made some progress after years of intensive behavioral and communication therapy, Carly remained largely unreachable. Then, at age 10, Carly had a breakthrough....

Crushed between a truck and a tree, Simon and his wife were both pronounced dead at the scene of a horrific car accident. Enduring a broken skull, jaw, arms, clavicle and pelvis, followed by a coma, Simon lives to tell his remarkable journey from tragedy to triumph.

Professor of psychiatry Elyn R. Saks writes about her struggle with schizophrenia in this unflinching account of her mental illness. In The Center Cannot Hold, Saks draws readers into a nightmare world of medications, a misguided health-care system, and social stigmas. But she would not be defeated. With a strength and force of will that most can only imagine, Saks reclaimed her life and went on to achieve great success.

At the age of thirty-six, on the verge of completing a decade’s worth of training as a neurosurgeon, Paul Kalanithi was diagnosed with stage IV lung cancer. One day he was a doctor treating the dying, and the next he was a patient struggling to live. And just like that, the future he and his wife had imagined evaporated.

The explosive new thriller from New York Times best-selling author and master of the medical thriller, Robin Cook. Lynn Peirce, a fourth-year medical student at South Carolina’s Mason-Dixon University, thinks she has her life figured out. But when her otherwise healthy boyfriend, Carl, enters the hospital for routine surgery, her neatly ordered life is thrown into total chaos. Carl fails to return to consciousness after the procedure, and an MRI confirms brain death. Devastated by Carl’s condition, Lynn searches for answers.

Leaving a life marked by crippling setbacks and his father's doubt, in 1967 a 20-something doctor from India arrived in America with only five dollars and the desire to claim his American dream. Faced with an entirely new culture, racism, and the lasting effects of disabling childhood injuries, through hard work and perseverance he overcame all odds. Now having performed over 15,000 open-heart surgeries, more than nearly every surgeon in history, Dr. Singh reflects on his most memorable patients and his incredible personal life.

For centuries, doctors have struggled to define mental illness - how do you diagnose it, how do you treat it, how do you even know what it is? In search of an answer, in the 1970s a Stanford psychologist named David Rosenhan and seven other people - sane, normal, well-adjusted members of society - went undercover into asylums around America to test the legitimacy of psychiatry's labels. Rosenhan's watershed study broke open the field of psychiatry, closing down institutions and changing mental health diagnosis forever.

For as long as writer Porochista Khakpour can remember, she has been sick. For most of that time, she didn't know why. All of her trips to the ER and her anguish, pain, and lethargy only ever resulted in one question: How could any one person be this sick? Several drug addictions, three major hospitalizations, and over $100,000 later, she finally had a diagnosis: late-stage Lyme disease. Sick is Khakpour's arduous, emotional journey - as a woman, a writer, and a lifelong sufferer of undiagnosed health problems - through the chronic illness that left her a victim of anxiety....

Dr. Jamison is one of the foremost authorities on manic-depressive (bipolar) illness; she has also experienced it firsthand. For even while she was pursuing her career in academic medicine, Jamison found herself succumbing to the same exhilarating highs and catastrophic depressions that afflicted many of her patients, as her disorder launched her into ruinous spending sprees, episodes of violence, and an attempted suicide.

Professor of psychiatry Elyn R. Saks writes about her struggle with schizophrenia in this unflinching account of her mental illness. In The Center Cannot Hold, Saks draws readers into a nightmare world of medications, a misguided health-care system, and social stigmas. But she would not be defeated. With a strength and force of will that most can only imagine, Saks reclaimed her life and went on to achieve great success.

Vince Granata remembers standing in front of his suburban home in Connecticut the day his mother and father returned from the hospital with his three new siblings in tow. He had just finished scrawling their names in orange chalk on the driveway: Christopher, Timothy, and Elizabeth. Twenty-three years later, Vince was a thousand miles away when he received the news that would change his life - his younger brother, Tim, propelled by unchecked schizophrenia, had killed their mother in their childhood home.

In 2015, Barbara Lipska - a leading expert on the neuroscience of mental illness - was diagnosed with melanoma that had spread to her brain. Within months, her frontal lobe, the seat of cognition, began shutting down. She descended into madness, exhibiting dementia- and schizophrenia-like symptoms that terrified her family and coworkers. But miraculously, the immunotherapy her doctors had prescribed worked quickly. Just eight weeks after her nightmare began, Lipska returned to normal. With one difference: she remembered her brush with madness with exquisite clarity.

For 200 years, a noble Venetian family has suffered from an inherited disease that strikes their members in middle age, stealing their sleep, eating holes in their brains, and ending their lives in a matter of months. In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. What these strange conditions share is their cause: prions.

In the summer of 2015, Ross Douthat was moving his family, with two young daughters and a pregnant wife, from Washington, DC, to a sprawling farmhouse in a picturesque Connecticut town when he acquired a mysterious and devastating sickness. It left him sleepless, crippled, wracked with pain - a shell of himself. After months of seeing doctors and descending deeper into a physical inferno, he discovered that he had a disease which, according to CDC definitions, does not actually exist.

Backbone is a life-fulfilling message about managing chronic pain and living a life of purpose. For two decades, Karen Duffy, New York Times bestselling author, former MTV VJ, Revlon model, and actress, has managed to live an enriching life despite living in a state of constant pain. In this powerful, inspirational, funny, and important manual for surviving pain, Duffy draws on her experience as a patient advocate, trained recreational therapist, and hospice chaplain to illuminate gratifying methods people can use to cope with chronic pain.

At the peak of his professional career, after having led the Asia Society for nearly a decade, Oxnam was haunted by periodic blackouts and episodic rages. After his family and friends intervened, Oxnam received help from a psychiatrist, Dr. Jeffery Smith, and entered a rehab center. It wasn't until 1990, during a session with Dr. Smith, that the first of Oxnam's 11 alternate personalities, an angry young boy named Tommy, suddenly emerged.