In the aftermath of her financier husband's suicide, Emma Shay Compton's dream life is shattered. Richard Compton stole his clients' life savings to fund a lavish life in New York City, and, although she was never involved in the business, Emma bears the burden of her husband's crimes. She is left with nothing. Only one friend stands by her, a friend she's known since high school, who encourages her to come home to Sonoma County. But starting over isn't easy, and Sonoma is full of unhappy memories, too.

Mrs. Sookie Poole of Point Clear, Alabama, has just married off the last of her daughters and is looking forward to relaxing and perhaps traveling with her husband, Earle. The only thing left to contend with is her mother, the formidable Lenore Simmons Krackenberry. Lenore may be a lot of fun for other people, but is, for the most part, an overbearing presence for her daughter. Then one day, quite by accident, Sookie discovers a secret about her mother's past that knocks her for a loop and suddenly calls into question everything she ever thought she knew about herself, her family, and her future.

Ginny Carter was once a rising star in TV news, married to a top anchorman, with a three-year-old son and a full and happy life in Beverly Hills - until her whole world dissolved in a single instant on the freeway two days before Christmas. In the aftermath, she pieces her life back together and tries to find meaning in her existence as a human rights worker in the worst areas around the globe.

It all starts with a fall from a ladder in a firehouse in New York City. The firehouse has been converted into a unique Manhattan home and studio where renowned photographer Madison Allen works and lives after raising three children on her own. But the accident, which happens while Maddie is sorting through long-forgotten personal mementos and photos, results in more than a broken ankle. It changes her life.

Betty Jean already has her hands full when her grown daughter leaves her two young sons in her care. In between dealing with her other adult children, two opinionated sisters, an ill husband, and her own postponed dreams - BJ still manages to hold down a job delivering room service at a hotel. Her son Dexter is about to be paroled from prison; Quentin, the family success, can’t be bothered to lend a hand; and taking care of two lively grandsons is the last thing BJ thinks she needs. But who asked her?

In 1977, pregnant Genevieve Russell disappeared. Twenty years later, her remains are discovered and Timothy Gleason is charged with murder. But there is no sign of the unborn child. CeeCee Wilkes knows how Genevieve Russell died, because she was there. And she also knows what happened to the missing infant, because two decades ago she made the devastating choice to raise the baby as her own. Now Timothy Gleason is facing the death penalty, and she has another choice to make: tell the truth, and destroy her family, or let an innocent man die in order to protect a lifetime of lies....

Bud Threadgoode grew up in the bustling little railroad town of Whistle Stop with his mother, Ruth, church-going and proper, and his Aunt Idgie, the fun-loving hell-raiser. Together they ran the town's popular Whistle Stop Cafe, known far and wide for its fun and famous fried green tomatoes. And as Bud often said of his childhood to his daughter, Ruthie, "How lucky can you get?"

Melissa Henderson is leading a quiet life. Once a best-selling author, she now pours all her energy into renovating a Victorian house nestled in the foothills of rural New England. Six years ago, she lost her young son to cancer, and her marriage dissolved. She stopped writing. Then Melissa receives a call from her sister, Hattie. They were close once, but that was before Melissa withdrew from the world. Now Hattie, who became a nun at 25, is determined to help Melissa turn a new page, even if it means reopening one of the most painful chapters of her life.

Oliver Watson's world suddenly dissolves around him when Sarah, his wife of 18 years, returns to Harvard to get her master's degree. Oliver is left on his own, with three children and a freedom he never wanted and doesn't completely understand. His family's needs and demands suddenly consume his life. When Oliver's mother is diagnosed as having Alzheimer's disease and dies soon thereafter, Oliver's father's life is changed, as well. Braver than his son with less of a future before him, George Watson, at 72, quickly embraces new relationships and, eventually, a new life.

Bill is a dedicated young lawyer working at his family’s prestigious New York firm, who leaves everything he trained for to follow his dream and become a minister in rural Wyoming. Jenny, his wife, is a stylist whose heart and soul are invested in fashion. She leaves the milieu and life she loves to join him. The certainty they share is that their destinies are linked forever.

Once Leota's garden was a place of beauty - where flowers bloomed and hope thrived. It was her refuge from the deep wounds inflicted by a devastating war, her sanctuary where she knelt before a loving God and prayed for the children who couldn't understand her silent sacrifices. At 83, Leota is alone; her beloved garden is in ruins. All her efforts to reconcile with her adult children have been fruitless. She voices her despair to a loving Father, her only friend. And God brings a wind of change through unlikely means....

On the outside, Faith Madison is the very picture of a sophisticated New Yorker. Slim, blond, stylish, Faith has a life many would envy. Overcoming a childhood marked by tragedy, married to a successful investment banker and having raised two grown daughters, Faith has enjoyed her role as mother and wife, and the good life that emanates from their bustling Manhattan town house. But every step of the way, Faith has carried within her a secret she could divulge to no one. And with it, she has kept an even more painful secret from herself.

Deidre Clark-Morris is a faithful Christian who has everything she could dream of - except the children her heart longs for. Kenisha Smalls has lived in poverty all her life. She has three children by three different men and has just been diagnosed with inoperable cancer. While the meeting between these two women appears accidental, it becomes their catalyst of hope. Neither woman expects the blessing that God has in store for her.

The Frosts are a typical American family. Barb and John, married almost 50 years, are testy and bored with each other...who could blame them after all this time? At least they have their daughters - Barb's favorite, the perfect, brilliant Juliet; and John's darling, the free-spirited Sadie. The girls themselves couldn't be more different, but at least they got along, more or less. It was fine. It was enough. Until the day John had a stroke, and their house of cards came tumbling down. Now Sadie has to put her career as a teacher and struggling artist in New York on hold....

Candy is blazing her way through Paris, New York, and Tokyo as fashion's latest supermodel. Her sister Tammy has a job producing a hit show on TV. In New York, oldest sister Sabrina is an ambitious young lawyer. And Annie is an American artist in Florence, living for her art. On one Fourth of July weekend, as they do every year, the four sisters come home to Connecticut for their family's annual gathering. But before the holiday is over, tragedy strikes, and their world is utterly changed.