A gripping journey of discovery, The Catalyst moves from the early experiments that first hinted at RNA's spectacular powers, to Cech's own paradigm-shifting finding that it can catalyze cellular reactions, to the cutting-edge biotechnologies poised to reshape our health.

The knowledge of death is so terrifying that we live most of our lives in denial of it. One of the most difficult moments of childhood must be when each of us first realizes that not only we but all our loved ones will die—and there is nothing we can do about it. Or at least, there hasn’t been. Today, we are living through a revolution in biology. Giant strides are being made in understanding why we age—and why some species live longer than others. Could we eventually cheat disease and death and live for a very long time, possibly many times our current lifespan?

In Waves in an Impossible Sea, physicist Matt Strassler tells a startling tale of elementary particles, human experience, and empty space. He begins with a simple mystery of motion. When we drive at highway speeds with the windows down, the wind beats against our faces. Yet our planet hurtles through the cosmos at 150 miles per second, and we feel nothing of it. How can our voyage be so tranquil when, as Einstein discovered, matter warps space, and space deflects matter? The answer, Strassler reveals, is that empty space is a sea, albeit a paradoxically strange one.

What is life? This is among the most difficult open problems in science, right up there with the nature of consciousness and the existence of matter. All the definitions we have fall short. None help us understand how life originates or the full range of possibilities for what life on other planets might look like. In Life as No One Knows It, physicist and astrobiologist Sara Imari Walker argues that solving the origin of life requires radical new thinking and an experimentally testable theory for what life is.

Conflict is increasing everywhere, threatening everything we hold dear—from our families to our democracy, from our workplaces to our world. In nearly every area of society, we are fighting more and collaborating less, especially over crucial problems that demand solutions. With this groundbreaking book, bestselling author and international negotiator William Ury shares a new “path to possible”—time-tested practices that will help listeners unlock their power to constructively engage and transform conflict.

Economic sanctions dominate the landscape of world politics today. First developed in the early twentieth century as a way of exploiting the flows of globalization to defend liberal internationalism, their appeal is that they function as an alternative to war. This view, however, ignores the dark paradox at their core: designed to prevent war, economic sanctions are modeled on devastating techniques of warfare.

Whether it's absent-minded mistakes at work, a weakness for junk food, a smartphone addiction, or a lack of exercise, everyone has some bad habit or behavior that they'd like to change. But wanting to change and actually doing it - and sticking with it - are two very different things. Dr. Sean Young, an authoritative new voice in the field of behavioral science, knows a great deal about our habits - how we make them and how we can break them.

How does a neural network become a brain? While neurobiologists investigate how nature accomplishes this feat, computer scientists interested in AI strive to achieve this through technology. The Self-Assembling Brain tells the stories of both fields, exploring the historical and modern approaches taken by the scientists pursuing answers to the quandary: What information is necessary to make an intelligent neural network? As Peter Robin Hiesinger argues, "the information problem" underlies both fields.

Scientists are learning more and more about how brain activity controls behavior and how neural circuits weigh alternatives and initiate actions. As we probe ever deeper into the mechanics of decision making, many conclude that agency—or free will—is an illusion. In Free Agents, leading neuroscientist Kevin Mitchell presents a wealth of evidence to the contrary, arguing that we are not mere machines responding to physical forces but agents acting with purpose.

Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

In Mitochondria and the Future of Medicine, naturopathic doctor Lee Know tells the epic story of mitochondria - the widely misunderstood and often-overlooked powerhouses of our cells. The legendary saga began over two billion years ago, when one bacterium entered another without being digested, which would evolve to create the first mitochondrion. Since then, for life to exist beyond single-celled bacteria, it's the mitochondria that have been responsible for this life-giving energy.

With the publication of Essay on the Principle of Population and its projection of food shortages in the face of ballooning populations, British theorist Thomas Robert Malthus secured a leading role in modern political and economic thought. In this startling new interpretation, Deborah Valenze reveals how canonical readings of Malthus fail to acknowledge his narrow understanding of what constitutes food production.

For innovation and leadership guru Hal Gregersen, the power of questions has always been clear - but it took some years for the follow-on question to hit him: If so much depends on fresh questions, shouldn’t we know more about how to arrive at them? That sent him on a research quest ultimately including more than 200 interviews with creative thinkers. Questions Are the Answer delivers the insights Gregersen gained about the conditions that give rise to catalytic questions - and breakthrough insights - and how anyone can create them.

Principles of Economics is a university-level textbook in economics that offers a clear and concise exploration of the most important economic concepts. This book is unapologetically Austrian in its approach. It tackles major economic concepts and topics independently, but in a logical sequence aimed at delivering the listener an understanding of economics at an individual and societal level, and the widespread implications of economics as a topic.

Chronic fatigue, burnout, brain fog-no matter what we call it, our constant feeling of being drained affects all that we hold dear. But the very real culprits of our fatigue don't lie in our preconceived notions of caffeine intake or adrenal fatigue, nor does the replenishment of our energy lie in overhauling our lifestyle in time-consuming and unrealistic ways. Instead, the core underlying cause lies in our cells, specifically our mitochondrial deficiency, and the solution can be found in simple, straightforward, nutritional strategies that address our body's biology.

The knowledge of death is so terrifying that we live most of our lives in denial of it. One of the most difficult moments of childhood must be when each of us first realizes that not only we but all our loved ones will die—and there is nothing we can do about it. Or at least, there hasn’t been. Today, we are living through a revolution in biology. Giant strides are being made in understanding why we age—and why some species live longer than others. Could we eventually cheat disease and death and live for a very long time, possibly many times our current lifespan?

A gripping journey of discovery, The Catalyst moves from the early experiments that first hinted at RNA's spectacular powers, to Cech's own paradigm-shifting finding that it can catalyze cellular reactions, to the cutting-edge biotechnologies poised to reshape our health.

Every day we draw in two thousand gallons of air—and thousands of living things. From the ground to the stratosphere, the air teems with invisible life. This last great biological frontier remains so mysterious that it took over two years for scientists to finally agree that the COVID pandemic was caused by an airborne virus. In Air-Borne, award-winning New York Times columnist and author Carl Zimmer leads us on an odyssey through the living atmosphere and through the history of its discovery.

We are living through a revolution in machine learning-powered AI that shows no signs of slowing down. This technology is based on relatively simple mathematical ideas, some of which go back centuries, including linear algebra and calculus, the stuff of seventeenth- and eighteenth-century mathematics. It took the birth and advancement of computer science and the kindling of 1990s computer chips designed for video games to ignite the explosion of AI that we see today. In this enlightening book, Anil Ananthaswamy explains the fundamental math behind machine learning.

Nvidia is the darling of the age of artificial intelligence: the company’s chips are powering the generative-AI revolution, and demand is insatiable. For all the current interest and attention, however, Nvidia is not of our time. Founded more than three decades ago in a Denny’s in East San Jose, for years it was known primarily in the then-niche world of computer gaming. In fact, the company’s leather-jacketed leader, Jensen Huang, is the longest-serving CEO in an industry marked by near constant turmoil and failure.