Tuesday Mooney is a loner. She keeps to herself, begrudgingly socializes, and spends much of her time watching old Twin Peaks and X-Files DVDs. But when Vincent Pryce, Boston’s most eccentric billionaire, dies—leaving behind an epic treasure hunt through the city, with clues inspired by his hero, Edgar Allan Poe—Tuesday’s adventure finally begins.

Inheriting your uncle's supervillain business is more complicated than you might think. Particularly when you discover who's running the place. Charlie's life is going nowhere fast. A divorced substitute teacher living with his cat in a house his siblings want to sell, all he wants is to open a pub downtown, if only the bank will approve his loan. Then his long-lost uncle Jake dies and leaves his supervillain business (complete with island volcano lair) to Charlie. But becoming a supervillain isn't all giant laser death rays and lava pits.

Opal is a lot of things—orphan, high school dropout, full-time cynic and part-time cashier—but above all, she's a determined to find a better life for her younger brother Jasper. One that gets them out of Eden, Kentucky, a town remarkable for only two things: bad luck and E. Starling, the reclusive nineteenth century author of The Underland, who disappeared over a hundred years ago. All she left behind were dark rumors—and her home. Everyone agrees that it’s best to ignore the uncanny mansion and its misanthropic heir, Arthur. Almost everyone, anyway.

Whether dueling with new forensics or the local old boys' network, irreverent defense attorney Andy Carpenter always leaves them awed with his biting wit and winning fourth-quarter game plan. But the fun stops the day Andy's dad, Paterson, New Jersey's legendary ex-DA, drops dead in front of him at a game in Yankee Stadium.

Billie, Mary Alice, Helen, and Natalie have worked for the Museum, an elite network of assassins, for 40 years. Now their talents are considered old-school and no one appreciates what they have to offer in an age that relies more on technology than people skills.

In a peaceful retirement village, four unlikely friends meet weekly in the Jigsaw Room to discuss unsolved crimes; together, they call themselves the Thursday Murder Club. When a local developer is found dead with a mysterious photograph left next to the body, the Thursday Murder Club suddenly find themselves in the middle of their first live case.

Feisty, passionate Beatrice Steele has never fit the definition of a true lady, according to the strict code of conduct that reigns in Swampshire, her small English township—she is terrible at needlework, has absolutely no musical ability, and her artwork is so bad it frightens people. Nevertheless, she lives a perfectly agreeable life with her marriage-scheming mother, prankster father, and two younger sisters— beautiful Louisa and forgettable Mary. But she harbors a dark secret: She is obsessed with the true crime cases she reads about in the newspaper.

As one of the few witches in Britain, Mika Moon knows she has to hide her magic, keep her head down, and stay away from other witches so their powers don’t mingle and draw attention. And as an orphan who lost her parents at a young age and was raised by strangers, she’s used to being alone and she follows the rules...with one exception: an online account, where she posts videos "pretending" to be a witch. She thinks no one will take it seriously.

Ellingham Academy is a famous private school in Vermont for the brightest thinkers, inventors, and artists. It was founded by Albert Ellingham, an early 20th century tycoon, who wanted to make a wonderful place full of riddles, twisting pathways, and gardens. "A place", he said, "where learning is a game." Shortly after the school opened, his wife and daughter were kidnapped. The only real clue was a mocking riddle listing methods of murder, signed with the frightening pseudonym "Truly, Devious".

A therapist and self-help writer with all the answers, Sarah has just bought a gorgeous Victorian in the community of her dreams. Turns out you can get a killer deal on a house where someone was murdered. Plus, renovating Black Wood House makes for great blog content and a potent distraction from her failing marriage. Good thing nobody knows that her past is as tainted as the bloodstain on her bedroom floor.

There are some odd things about Nate’s new apartment. Of course, he has other things on his mind. He hates his job. He has no money in the bank. No girlfriend. No plans for the future. So while his new home isn’t perfect, it’s livable. The rent is low, the property managers are friendly, and the odd little mysteries don’t nag at him too much. At least, not until he meets Mandy, his neighbor across the hall, and notices something unusual about her apartment. And Xela’s apartment. And Tim’s. And Veek’s.

Harriet Vanger, a scion of one of Sweden's wealthiest families disappeared over forty years ago. All these years later, her aged uncle continues to seek the truth. He hires Mikael Blomkvist, a crusading journalist recently trapped by a libel conviction, to investigate. He is aided by the pierced and tattooed punk prodigy Lisbeth Salander. Together they tap into a vein of unfathomable iniquity and astonishing corruption.

Libby Day was seven when her mother and two sisters were murdered in "The Satan Sacrifice of Kinnakee, Kansas". As her family lay dying, little Libby fled their tiny farmhouse into the freezing January snow. She lost some fingers and toes, but she survived, and famously testified that her 15-year-old brother, Ben, was the killer. Twenty-five years later, Ben sits in prison, and troubled Libby lives off the dregs of a trust created by well-wishers who've long forgotten her.

When Arlene Fleet heads up north for college, she makes three promises to God: She will stop fornicating with every boy who crosses her path; never tell another lie; and never, ever go back to the "fourth rack of hell", her hometown of Possett, Alabama. All she wants from Him is one little miracle: make sure the body is never found.

The ornate reading room at the Boston Public Library is quiet—until the tranquility is shattered by a woman's terrified scream. Security guards take charge immediately, instructing everyone inside to stay put until the threat is identified and contained. While they wait for the all-clear, four strangers, who'd happened to sit at the same table, pass the time in conversation, and friendships are struck. Each has his or her own reasons for being in the reading room that morning—it just happens that one is a murderer.