In the near future, disease will be a condition of the past. Most genetic defects will be removed at birth; the remaining during infancy. Unfortunately, there will be a generation left behind. For members of that missed generation, small advances will be made. Through various programs, they will be taught to get along in the world despite their differences. They will be made active and contributing members of society. But they will never be normal.

Old-school lawyer Albert Schmidt has spent years carefully climbing the ladder of success. But now, at what should be the pinnacle of his career, his life is in chaos. Within months, he is widowed and forcibly retired from his firm. He harbors painfully mixed feelings about his ambitious daughter’s impending marriage. Suddenly, in the midst of this turmoil, a seductive young woman asks Smitty what he wants. Far from being a time of satisfaction and complacency, the middle age encountered by Begley’s hero is the beginning of a new journey—tantalizing, yet unnerving.

Born a Parsi in Bombay, sent to university and medical school in Vienna, Dr. Farrokh Daruwalla is a 59-year-old orthopedic surgeon and a Canadian citizen who lives in Toronto. Once, 20 years ago, Dr. Daruwalla was the examining physician of two murder victims in Goa, India. Now, 20 years later, he will be reacquainted with the murderer.

This beautiful and haunting novel bares the soul of a Hawaiian-American family during World War II. As you share in the Meahuna family's misfortunes and triumphs, a sense of intense intimacy evolves. Cristine McMurdo-Wallis lets you savor the family members' remarkable, heartwrenching stories as they are revealed piece by piece in language rich with sensuous detail.

Charlotte Davis is in pieces. At 17 she's already lost more than most people do in a lifetime. But she's learned how to forget. The broken glass washes away the sorrow until there is nothing but calm. You don't have to think about your father and the river. Your best friend, who is gone forever. Or your mother, who has nothing left to give you. Every new scar hardens Charlie's heart just a little more, yet it still hurts so much. It hurts enough to not care anymore, which is sometimes what has to happen before you can find your way back from the edge.

Meet Dolores Price. She's 13, wise-mouthed but wounded, having bid her childhood goodbye. Beached like a whale in front of her bedroom TV, she spends the next few years nourishing herself with the Mallomars, potato chips, and Pepsi her anxious mother supplies. When she finally rolls into young womanhood at 257 pounds, Dolores is no stronger and life is no kinder. But this time she's determined to rise to the occasion and give herself one more chance before really going belly-up.

Thirteen-year-old Julie Whitaker was kidnapped from her bedroom in the middle of the night, witnessed only by her younger sister. Her family was shattered, but managed to stick together, hoping against hope that Julie is still alive. And then one night: the doorbell rings. A young woman who appears to be Julie is finally, miraculously, home safe. The family is ecstatic - but Anna, Julie's mother, has whispers of doubts. She hates to face them.

Seventeen-year-old Molly Fisk does not go outside. She's ruled by anxiety and only feels safe in the tiny tourist-town museum she and her mother run and call home. Yearning to live free but unable to overcome deep wounds from her past, she stays hidden away. Then the chance arrival of a woman Molly knew six years ago changes everything.

Therese Wolley is a mother who has made a promise. She works as a secretary, shops for groceries on Saturdays, and takes care of her two girls. She doesn’t dwell on the fact that her girls are fatherless, mostly because her own father abandoned her before she was born and she has done just fine without him. Even though her older daughter regularly wakes with nightmares and her younger one whispers letters under her breath, she doesn't shift from her resolve that everything will be fine.

In this gripping first novel, a young girl, orphaned when her mother murders an ex-lover, endures the shuffle of a foster child's life. Oprah enjoyed her book club pick so much that she narrates the audiobook edition!

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Seabiscuit was one of the most electrifying and popular attractions in sports history and the single biggest newsmaker in the world in 1938, receiving more coverage than FDR, Hitler, or Mussolini. But his success was a surprise to the racing establishment, which had written off the crooked-legged racehorse with the sad tail.

It’s 2013, and Circus Palmer, a 40-year-old Boston-based trumpet player and old-school ladies’ man, lives for his music and refuses to be tied down. Before a gig in Miami, he learns that the woman who is secretly closest to his heart, the free-spirited drummer Maggie, is pregnant by him.

Everything about 15-year-old Cat's new town in rural Michigan is lonely and off-kilter until she meets her neighbor, the manic, beautiful, pill-popping Marlena. Cat, inexperienced and desperate for connection, is quickly lured into Marlena's orbit by little more than an arched eyebrow and a shake of white-blond hair. As the two girls turn the untamed landscape of their desolate small town into a kind of playground, Cat catalogues a litany of firsts - first drink, first cigarette, first kiss - while Marlena's habits harden and calcify.

Fifteen-year-old Ilya arrives in Louisiana from his native Russia for what should be the adventure of his life: a year in America as an exchange student. But all is not right in Ilya's world: He's consumed by the fate of his older brother, Vladimir, the magnetic rebel to Ilya's dutiful wunderkind, back in their tiny Russian hometown. Just before Ilya left, the murders of three young women rocked the town's usual calm, and Vladimir found himself in prison. With the help of Sadie, who has secrets of her own, Ilya embarks on a mission to prove Vladimir's innocence.

The wealthy enclaves north of San Francisco are not the paradise they appear to be, and nobody knows this better than the students of a local high school. Despite being raised with all the opportunities money can buy, these vulnerable kids are navigating a treacherous adolescence in which every action, every rumor, every feeling, is potentially postable, shareable, viral.

Everything about 15-year-old Cat's new town in rural Michigan is lonely and off-kilter until she meets her neighbor, the manic, beautiful, pill-popping Marlena. Cat, inexperienced and desperate for connection, is quickly lured into Marlena's orbit by little more than an arched eyebrow and a shake of white-blond hair. As the two girls turn the untamed landscape of their desolate small town into a kind of playground, Cat catalogues a litany of firsts - first drink, first cigarette, first kiss - while Marlena's habits harden and calcify.

Meet Dolores Price. She's 13, wise-mouthed but wounded, having bid her childhood goodbye. Beached like a whale in front of her bedroom TV, she spends the next few years nourishing herself with the Mallomars, potato chips, and Pepsi her anxious mother supplies. When she finally rolls into young womanhood at 257 pounds, Dolores is no stronger and life is no kinder. But this time she's determined to rise to the occasion and give herself one more chance before really going belly-up.

On the surface, Niru leads a charmed life. Raised by two attentive parents in Washington, DC, he's a top student and a track star at his prestigious private high school. Bound for Harvard in the fall, his prospects are bright. But Niru has a painful secret: He is queer - an abominable sin to his conservative Nigerian parents. No one knows except Meredith, his best friend, the daughter of prominent Washington insiders - and the one person who seems not to judge him.

Two cousins, Rory and Arden, lie unconscious in a hospital burn unit. The fire, which broke out in their shared college dorm room, killed another student, and the police want answers. Tension between Rory and Arden's parents was already at an all-time high before the fire, owing to a recent financial crisis and the decline of the family business. As the parents huddle anxiously in the waiting room, carefully avoiding the subject of their own unraveling relationships, disturbing truths come to light.

Margo is not like other girls. She lives in a derelict neighborhood called the Bone, in a cursed house, with her cursed mother, who hasn't spoken to her in over two years. She lives her days feeling invisible. It's not until she develops a friendship with her wheelchair-bound neighbor, Judah Grant, that things begin to change. When a neighborhood girl, seven-year-old Neveah Anthony, goes missing, Judah sets out to help Margo uncover what happened to her. What Margo finds changes her, and with a new perspective on life she's determined to find evil and punish it.

Liz Murray was born to loving but drug-addicted parents in the Bronx. In school she was taunted for her dirty clothing and lice-infested hair, eventually skipping so many classes that she was put into a girls' home. At age 15, Liz found herself on the streets when her family finally unraveled. She learned to scrape by, foraging for food and riding subways all night to have a warm place to sleep. Then, when Liz's mother died of AIDS, she decided to take control of her own destiny.

Diane McKinney-Whetstone, the award-winning and best-selling author of Tumbling, presents Trading Dreams at Midnight - - an Essence Book Club Recommended Read. Back in 1984, 15-year-old Neena's mother left and never came back. And now Neena is following in her footsteps.

There's something eerily unsettling about Ottessa Moshfegh's stories, something almost dangerous, while also being delightful and even laugh-out-loud funny. Her characters are all unsteady on their feet in one way or another; they all yearn for connection and betterment, though each in very different ways, but they are often tripped up by their own baser impulses and existential insecurities.

Angela is being held in a police interrogation room. Her ex's wife has gone missing, and Detective Novak is sure Angela knows something, despite her claim that she's not involved. At Novak's prodding, Angela tells a story going back 10 years, explaining how she met and fell in love with her high school friend HP. But as her past unfolds, she reveals a disconcerting love triangle and a dark, tangled web of betrayals. Is Angela a scorned ex-lover with criminal intent? Or a pawn in someone else's revenge scheme?

The world as we know it is ending. Evolution has reversed itself, affecting every living creature on earth. Science cannot stop the world from running backward, as woman after woman gives birth to infants that appear to be primitive species of humans. Thirty-two-year-old Cedar Hawk Songmaker, adopted daughter of a pair of big-hearted, open-minded Minneapolis liberals, is as disturbed and uncertain as the rest of America around her. But for Cedar, this change is profound and deeply personal. She is four months pregnant.

Sixteen-year-old Sayers Wayte has everything. Popularity, good looks, perfect grades—there's nothing Sayers' family money can't buy. Until he's kidnapped by a man who tells him the privileged life he's been living is based on a lie. Trapped in a windowless room, without knowing why he's been taken or how long the man plans to keep him shut away, Sayers faces a terrifying new reality. To survive, he must forget the world he once knew, and play the part his abductor has created for him.

Seven-year-old Chula and her older sister, Cassandra, enjoy carefree lives thanks to their gated community in Bogotá, but the threat of kidnappings, car bombs, and assassinations hover just outside the neighborhood walls, where the godlike drug lord Pablo Escobar continues to elude authorities and capture the attention of the nation. When their mother hires Petrona, a live-in-maid from the city's guerrilla-occupied slum, Chula makes it her mission to understand Petrona's mysterious ways.

Rabbit, Run is the book that established John Updike as one of the major American novelists of his - or any other - generation. Its hero is Harry “Rabbit” Angstrom, a onetime high-school basketball star who on an impulse deserts his wife and son. He is 26 years old, a man-child caught in a struggle between instinct and thought, self and society, sexual gratification and family duty - even, in a sense, human hard-heartedness, and divine Grace. Though his flight from home traces a zigzag of evasion, he holds to the faith that he is on the right path.

In her tour-de-force first novel, Juliann Garey takes us inside the restless mind, ravaged heart, and anguished soul of Greyson Todd, a successful Hollywood studio executive who leaves his wife and young daughter and for a decade travels the world giving free reign to the bipolar disorder he's been forced to keep hidden for almost 20 years.

In 1965 Manhattan, patrons flock to Masha’s to savor its brisket bourguignon and impeccable service and to admire its dashing owner and head chef Peter Rashkin, the most eligible bachelor in town. But Peter does not care for the parade of eligible women who come to the restaurant hoping to catch his eye. Running Masha’s consumes him, as does his terrible guilt over surviving the horrors of the Nazi death camp while his wife, Masha - the restaurant’s namesake - and two young daughters perished. Then exquisitely beautiful June Bouquet, an up-and-coming young model, appears at the restaurant, piercing Peter’s guard.