It’s been thirteen years since doctors declared Libby Ross-Velasquez a goner. Yet here she is - cancer-free. So why doesn’t she feel more alive? Sure, Libby’s husband, Shiloh, has been distant. One of their daughters has a serious health condition. And her father’s death hovers over Libby like a rain cloud. Still, this eternal optimist knows she’s the winner of the existential lottery. But when her forced cheer isn’t enough to keep her family from catching her blahs, she decides to fly them all to Vieques. The Puerto Rican island is where she and Shiloh fell in love.

Overworked and underappreciated, single mom Amy Byler needs a break. So when the guilt-ridden husband who abandoned her shows up and offers to take care of their kids for the summer, she accepts his offer and escapes rural Pennsylvania for New York City. Usually grounded and mild mannered, Amy finally lets her hair down in the city that never sleeps. She discovers a life filled with culture, sophistication, and - with a little encouragement from her friends - a few blind dates.

Aly Jackson has waited her whole life to become editor in chief of All Good magazine. But six months into the job, she overhears her coworkers belittling her. Aly’s clapback? A very public, career-jeopardizing meltdown. To undo the mess, she agrees to a monthlong unpaid leave. Reluctant but determined to turn misfortune into opportunity, Aly retreats to the Lake Michigan beach house her brother, Luke, left to her when he died nearly a year earlier. Except when Aly arrives, she discovers Luke’s slacker best friend, Wyatt, inherited the place, too.

Wife. Mother. Breadwinner. Penelope Ruiz-Kar is doing it all - and barely keeping it together. Meanwhile, her best friend, Jenny Sweet, appears to be sailing through life. As close as the two women are, Jenny’s passionate marriage, pristine house, and ultra-polite child stand in stark contrast to Penelope’s underemployed husband, Sanjay, their unruly brood, and the daily grind she calls a career.

Laine Francis believes there’s a place for everything—and New York, where her family lives, isn’t her place. But no sooner does the professional organizer’s marriage begin to unravel than her sisters drop another bomb on her: their mother, Sally, may have dementia, and they need Laine to come home.

No new people: that's Annie Mercer's vow. It's bad enough that her boss sabotaged her chemistry career and her best friend tried to cure her with crystals. But after her fiancé, Jon, asks for space while he's gallivanting around Paris, Annie decides she needs space too - from everyone. Yet when Harper moves in next door, Annie can't help but train a watchful eye on the glamorous but fragile young woman. And if keeping Harper safe requires teaming up with Mo, a maddeningly optimistic amateur detective, who is she to mind her own business?

When struggling novelist James Hernandez meets poet Louisa "Lou" Bell, he's sure he's just found the love of his life. There's just one problem: she's engaged to his oldest friend, Rob. So James toasts their union and swallows his desire. As the years pass, James's dreams always seem just out of reach - he can't finish that novel, can't mend his relationship with his father, can't fully commit to a romantic relationship. He just can't move on.

Romance writer Penelope Banks can write the perfect love story, but when it comes to family, all she’s got is a rough draft. Penny shelved the idea of fitting in with her high-achieving family years ago, but when her new business venture—a romance bookstore—is at risk of closing before its doors have opened, she’s forced to ask for help from the one place she never expected. Home.

After three marriages and a lot of living, resilient Billie Slate knows exactly what trouble love can bring. Now she’s reinvented herself as the Heartbreak Bunny, an on-call performance artist who can heal anyone who’s been burned by that four-letter word, LOVE, by hopping about and whisking away sad mementos from their past relationships. Call it magic. Call it peculiar. But her bunny costume is as perfect as her breakup mantra: SNAP OUT OF IT.

It seems lately that Poppy Lively is invisible to everyone but the IRS. After her accountant absconded with her life savings, newly bankrupt Poppy is on the verge of losing her home when an old flame, now a hotshot producer, gives her a surprising way out: a job in costumes on a Hollywood film set. It’s a bold move to pack her bags, keep secrets from her daughter, and head to Los Angeles, but Poppy's a capable person—how hard can a job in wardrobe be?

Widower Noah Shilling considers Clarion Court to be less an independent living community and more a prison. But there may be hope for the place yet. The newest resident is bold, eccentric, rule-breaking Cassandra Joyce—whom, as it turns out, Noah met long ago in college. As Noah and Cassandra get reacquainted, major changes at Clarion Court force them both to reevaluate their living situation. When Noah invites Cassandra to rough it with him at his Cape Cod cottage, the old friends must decide whether they should risk embarking on the next stage of their journey together.

Planning the perfect prom is one last “to do” on ultra-organized Charlotte Wu’s high school bucket list. So far, so good, if not for a decorating accident that sends Charlotte crash-landing off a ladder, face-first into her obnoxiously ripped archnemesis J. T. Renner. Worse? When Charlotte wakes up, she finds herself in an unfamiliar bed at thirty years old, with her bearded fiancé, Renner, by her side.

As one of the most popular influencers on social media, Mia Bell has lived her life online for years. With her celebrity dog and gorgeous fiancé, she is planning the ultimate virtual wedding - expensive, elaborate, and entirely paid for by sponsors. But off-camera, her world is far from picture perfect. After being jilted by her fiancé and faking her nuptials to please her sponsors, Mia finally has had enough. She heaves her phone off a cliff, ready to live - and maybe find love - offline for a change.

Marnie MacGraw and Patrick Delaney have been in love for a few years now, enough to realize that they are imperfectly perfect together. Still, there are some things that maybe need a little attention. Marnie’s ebullient; he’s brooding. She thrives on change; he prefers stability. She sees marriage and parenthood in their future, but he can’t see beyond the shadow of an earlier tragedy. Then an eight-year-old surprise from Patrick’s past shows up on their doorstep, cartwheeling into their lives and spinning things in all directions.

In the turbulent summer of 1974, Kate Mularkey has accepted her place at the bottom of the eighth-grade social food chain. Then, to her amazement, the "coolest girl in the world" moves in across the street and wants to be her friend. Tully Hart seems to have it all - beauty, brains, ambition. On the surface they are as opposite as two people can be: Kate, doomed to be forever uncool, with a loving family who mortifies her at every turn.