Aly Jackson has waited her whole life to become editor in chief of All Good magazine. But six months into the job, she overhears her coworkers belittling her. Aly’s clapback? A very public, career-jeopardizing meltdown. To undo the mess, she agrees to a monthlong unpaid leave. Reluctant but determined to turn misfortune into opportunity, Aly retreats to the Lake Michigan beach house her brother, Luke, left to her when he died nearly a year earlier. Except when Aly arrives, she discovers Luke’s slacker best friend, Wyatt, inherited the place, too.

It’s been thirteen years since doctors declared Libby Ross-Velasquez a goner. Yet here she is - cancer-free. So why doesn’t she feel more alive? Sure, Libby’s husband, Shiloh, has been distant. One of their daughters has a serious health condition. And her father’s death hovers over Libby like a rain cloud. Still, this eternal optimist knows she’s the winner of the existential lottery. But when her forced cheer isn’t enough to keep her family from catching her blahs, she decides to fly them all to Vieques. The Puerto Rican island is where she and Shiloh fell in love.

As one of the most popular influencers on social media, Mia Bell has lived her life online for years. With her celebrity dog and gorgeous fiancé, she is planning the ultimate virtual wedding - expensive, elaborate, and entirely paid for by sponsors. But off-camera, her world is far from picture perfect. After being jilted by her fiancé and faking her nuptials to please her sponsors, Mia finally has had enough. She heaves her phone off a cliff, ready to live - and maybe find love - offline for a change.

Libby Miller has always been an unwavering optimist - but when her husband drops a bomb on their marriage the same day a doctor delivers devastating news, she realizes her rose-colored glasses have actually been blinding her. With nothing left to lose, she abandons her life in Chicago for the clear waters and bright beaches of the Caribbean for what might be her last hurrah.

At fifty-three, Maggie Harris has a good marriage and two mostly happy children. Perpetually anxious, she’s also accumulated a list of semi-reasonable fears: falling air conditioners, the IRS, identity theft, skydiving, and airbag recalls. But never once did Maggie worry that her husband of nearly thirty years would leave her.

No new people: that's Annie Mercer's vow. It's bad enough that her boss sabotaged her chemistry career and her best friend tried to cure her with crystals. But after her fiancé, Jon, asks for space while he's gallivanting around Paris, Annie decides she needs space too - from everyone. Yet when Harper moves in next door, Annie can't help but train a watchful eye on the glamorous but fragile young woman. And if keeping Harper safe requires teaming up with Mo, a maddeningly optimistic amateur detective, who is she to mind her own business?

Overworked and underappreciated, single mom Amy Byler needs a break. So when the guilt-ridden husband who abandoned her shows up and offers to take care of their kids for the summer, she accepts his offer and escapes rural Pennsylvania for New York City. Usually grounded and mild mannered, Amy finally lets her hair down in the city that never sleeps. She discovers a life filled with culture, sophistication, and - with a little encouragement from her friends - a few blind dates.

When struggling novelist James Hernandez meets poet Louisa "Lou" Bell, he's sure he's just found the love of his life. There's just one problem: she's engaged to his oldest friend, Rob. So James toasts their union and swallows his desire. As the years pass, James's dreams always seem just out of reach - he can't finish that novel, can't mend his relationship with his father, can't fully commit to a romantic relationship. He just can't move on.

Marnie MacGraw wants an ordinary life - a husband, kids, and a minivan in the suburbs. Now that she’s marrying the man of her dreams, she’s sure this is the life she’ll get. Then Marnie meets Blix Holliday, her fiancé’s irascible matchmaking great-aunt who’s dying, and everything changes - just as Blix told her it would. When her marriage ends after two miserable weeks, Marnie is understandably shocked.

When Mackenzie, Sunna, and Maude move into a converted rental house, they are strangers with only one thing in common - important people in their lives have “ghosted” them. Mackenzie’s sister, Sunna’s best friend, and Maude’s fiancé - all gone with no explanation. So when a mangled, near-indecipherable letter arrives in their shared mailbox - hinting at long-awaited answers - each tenant assumes it’s for her.

As a teenage runaway and child of an addict, Christy-Lynn learned the hard way that no address was permanent, and no promise sacred. For a while, she found a safe haven in her marriage to bestselling crime novelist Stephen Ludlow - until his car skidded into Echo Bay. But Stephen’s wasn’t the only body pulled from the icy waters that night. When details about a mysterious violet-eyed blonde become public, a media circus ensues, and Christy-Lynn runs again.

Phronsie Linnelle was conceived at Woodstock in a serendipitous liaison between a free-spirited hippie and a farmer’s son and was born with magical wonder flickering in her DNA and rationality knit into her bones. All her life she’s been torn between the two. But now that she’s been betrayed by both love and the mother she once idolized, her rational side is winning. So when her best friend from childhood proposes that they give up on romance and marry each other, Phronsie agrees.

It seems lately that Poppy Lively is invisible to everyone but the IRS. After her accountant absconded with her life savings, newly bankrupt Poppy is on the verge of losing her home when an old flame, now a hotshot producer, gives her a surprising way out: a job in costumes on a Hollywood film set. It’s a bold move to pack her bags, keep secrets from her daughter, and head to Los Angeles, but Poppy's a capable person—how hard can a job in wardrobe be?

Cleo McDougal is a born politician. From congresswoman to senator, the magnetic, ambitious single mother now has her eye on the White House - always looking forward, never back. Until an estranged childhood friend shreds her in an op-ed hit piece gone viral. With seven words - "Cleo McDougal is not a good person" - the presidential hopeful has gone from in control to damage control, and not just in Washington but in life.

At 32 Russell Green has it all: a stunning wife, a lovable six-year-old daughter, a successful career as an advertising executive, and an expansive home in Charlotte. He is living the dream, and his marriage to the bewitching Vivian is the center of that. But underneath the shiny surface of this perfect existence, fault lines are beginning to appear, and no one is more surprised than Russ when he finds every aspect of the life he took for granted turned upside down.