For two thousand years, cadavers have been involved in science's boldest strides and weirdest undertakings. They've tested France's first guillotines, ridden the NASA Space Shuttle, been crucified in a Parisian laboratory to test the authenticity of the Shroud of Turin, and helped solve the mystery of TWA Flight 800. For every new surgical procedure, from heart transplants to gender reassignment surgery, cadavers have been there alongside surgeons, making history in their quiet way.

Backbone is a life-fulfilling message about managing chronic pain and living a life of purpose. For two decades, Karen Duffy, New York Times bestselling author, former MTV VJ, Revlon model, and actress, has managed to live an enriching life despite living in a state of constant pain. In this powerful, inspirational, funny, and important manual for surviving pain, Duffy draws on her experience as a patient advocate, trained recreational therapist, and hospice chaplain to illuminate gratifying methods people can use to cope with chronic pain.

With poignant insight and humor, Frank Vertosick, Jr., MD, describes some of the greatest challenges of his career, including a six-week-old infant with a tumor in her brain, a young man struck down in his prime by paraplegia, and a minister with a .22-caliber bullet lodged in his skull. Told through intimate portraits of Vertosick's patients and unsparing-yet-fascinatingly detailed descriptions of surgical procedures, When the Air Hits Your Brain illuminates both the mysteries of the mind and the realities of the operating room.

A hilarious and emotional personal account of the life, times, mistakes, and crippling codependence of comedian, producer, director, actress, and writer Whitney Cummings. Full of intellect, pathos, and profundity, I'm Fine...and Other Lies is, in Whitney's words, her first book, which means her last date. With her signature incendiary edge and self-deprecation, Whitney comes clean about what has shaped her into the trailblazing comic that she is today.

Sometimes in medicine the only way to know what is truly going on in a patient is to operate, to look inside with one's own eyes. This book is exploratory surgery on medicine itself, laying bare a science not in its idealized form but as it actually is - complicated, perplexing, and profoundly human.

America's Angriest Trainer, Vinnie Tortorich, exposes the nasty underbelly of the fitness industry while getting you into the best shape of your life. For over 20 years, Vinnie has been Hollywood's go-to guy for celebrities and athletes looking to get fit fast. Now, in this hilarious and often R-rated memoir, he holds nothing back. What's the best piece of fitness equipment money can buy? What's the fastest way to lose weight: diet or exercise? Why are health clubs worse than used car lots? In Fitness Confidential, Vinnie tells all.

When 24-year-old Susannah Cahalan woke up alone in a hospital room, strapped to her bed and unable to move or speak, she had no memory of how she’d gotten there. Days earlier, she had been on the threshold of a new, adult life: At the beginning of her first serious relationship and a promising career at a major New York newspaper. Now she was labeled violent, psychotic, a flight risk. What happened?

Rapper and singer Dessa gives a candid account of her life as a touring musician, her determination to beat long odds to make a name for herself, and her struggle to fall out of love with someone in her band. Raw and intimate, Dessa demonstrates just how far the mind can travel while the body is on the six-hour ride to the next rap show. Dessa finds unconventional approaches to all of her subjects - braiding her lived experience with academic research and a poet's tone and timing. In the vein of thinkers who defy categorization, we get the debut of a deft, likable, and unusual voice.

Dr. Kathy Magliato is one of fewer than a dozen female heart surgeons practicing in the world today. She is also a member of an even more exclusive group - those surgeons who perform heart transplants. Healing Hearts is the story of the making of a surgeon who also calls herself a wife and mother.

Tumors, injuries, ruptured vascular malformations—there is almost no such thing as a non-urgent brain surgery when it comes to kids. For a pediatric neurosurgeon working in the medical minefield of the brain—in which a single millimeter in every direction governs something that makes us essentially human—every day presents the challenge, and the opportunity, to give a new lease on life to a child for whom nothing is yet fully determined and all possibilities still exist.

In 1972, at the age of 21, John Callahan was involved in a car crash that severed his spine and made him a quadriplegic. A heavy drinker since the age of 12, the accident could have been the beginning of a downward spiral. Instead, it sparked a personal transformation. After extensive physical therapy, he was eventually able to grasp a pen in his right hand and make rudimentary drawings. By 1978, Callahan had sworn off drinking for good and begun to draw cartoons. Over the next three decades, Callahan would become one of the nation's most beloved cartoonists.

Julia Fox Garrison refused to listen to the professionals she called Dr. Jerk and Dr. Panic, who - after she suffered a massive, debilitating stroke at age thirty-seven - told her she’d probably die, or to Nurse Doom, who ignored her emergency call button. Instead she heeded the advice of kind, gifted Dr. Neuro, who promised her he would “treat your mind as well as your body.” Julia figured if she could somehow manage to get herself into a wheelchair, at least she’d always find parking. But after many, many months of hospitalization and rehab, Julia not only got into a wheelchair, but she got back out.

Whether it's family history, religion, aging, or his parents, Michael Ian Black always has something to say in the dry, irreverent voice that has captured a fan base of millions. When a medical diagnosis forces him to realize he's not getting any younger, he reexamines his life as a middle-aged guy - of course, in the deadpan wit and self-deprecating vignettes that have become trademarks of his humor.

A. J. Jacobs tackles his most challenging experiment yet: a yearlong mission to radically improve every element of his body and mind - from his brain to his fingertips to his abs. First, he had to tackle a complicated web of diet and exercise advice, most which is nonsensical, unproven, and contradictory. Second, he had to consult a team of medical advisers. And finally, he had to subject himself, over the course of two years, to a grueling regimen of exercises and a range of diets and nutritional plans.

It was a beautiful fall day in Connecticut when Colleen Kelly Alexander, a lifelong athlete, rode her bike home from work. She had survived both a diagnosis of lupus and brain surgery, had a fulfilling career, and was married at last to the love of her life. Everything was good as she coasted along, meeting the eyes of a truck driver as he approached the stop sign beside her. He didn't stop. The truck hit Colleen, running over her lower body with front and back tires and dragging her across the pavement.

Dr. Kathy Magliato is one of fewer than a dozen female heart surgeons practicing in the world today. She is also a member of an even more exclusive group - those surgeons who perform heart transplants. Healing Hearts is the story of the making of a surgeon who also calls herself a wife and mother.

Julia Fox Garrison refused to listen to the professionals she called Dr. Jerk and Dr. Panic, who - after she suffered a massive, debilitating stroke at age thirty-seven - told her she’d probably die, or to Nurse Doom, who ignored her emergency call button. Instead she heeded the advice of kind, gifted Dr. Neuro, who promised her he would “treat your mind as well as your body.” Julia figured if she could somehow manage to get herself into a wheelchair, at least she’d always find parking. But after many, many months of hospitalization and rehab, Julia not only got into a wheelchair, but she got back out.

Marine Sgt. John Peck survived an IED during the War on Terror that left him with a traumatic brain injury, amnesia, and cost him his marriage. He survived another three years later, one that left him with three and a half limbs missing. He’s one of only two living people to survive the flesh-eating fungus he contracted in recovery at Walter Reed, one that left him as a quadruple amputee. And that’s only the beginning of his story. What followed was a recovery nothing short of miraculous.

Crushed between a truck and a tree, Simon and his wife were both pronounced dead at the scene of a horrific car accident. Enduring a broken skull, jaw, arms, clavicle and pelvis, followed by a coma, Simon lives to tell his remarkable journey from tragedy to triumph.

In the early evening on October 1, 2003, Christina Crosby was three miles into a 17 mile bicycle ride, intent on reaching her goal of 1,000 miles for the riding season. She was a respected senior professor of English who had celebrated her 50th birthday a month before. As she crested a hill, she caught a branch in the spokes of her bicycle, which instantly pitched her to the pavement. Her chin took the full force of the blow, and her head snapped back. In that instant, she was paralyzed.

In What Makes Olga Run? Bruce Grierson explores what the wild success of a 94-year-old track star can tell us about how our bodies and minds age. Olga Kotelko is not your average 94-year-old. She not only looks and acts like a much younger woman, she holds over 23 world records in track and field, 17 in her current 90 to 95 category. Convinced that this remarkable woman could help unlock many of the mysteries of aging, Grierson set out to uncover what it is that's driving Olga.

With acerbic wit and a hilarious voice, Shane Burcaw's Laughing at My Nightmare describes the challenges he faces as a 21-year-old with spinal muscular atrophy. From awkward handshakes to having a girlfriend and everything in between, Shane handles his situation with humor and a "you-only-live-once" perspective on life. While he does talk about everyday issues that are relatable to teens, he also offers an eye-opening perspective on what it is like to have a life threatening disease

True Grit and Grace tells the story of a woman's life forever altered by a horrific motorcycle accident that shattered her right leg. Despite the initial recommendation to amputate, she endured 34 surgeries to save it. However, as a sexual-abuse and divorce survivor, she determined to save not only her leg, but her career, her dreams, and her dignity.

From the frontlines of modern medicine, Tell Me Where it Hurts is a fascinating insider portrait of a veterinarian, his furry patients, and the blend of old-fashioned instincts and cutting-edge technology that defines pet care in the 21st century. Dr. Trout takes the listener on a vicarious journey through 24 intimate, heartrending hours in his life.

Mark Zupan, a quadriplegic, was facing life in a wheelchair and only limited use of all four limbs. Always a winner and a fighter, Mark refused to accept that his injury doomed him to a lifetime of passive acceptance. He fought to regain as much mobility as possible, and his indomitable spirit has helped him create a life that's truly exceptional.

In 2015, Barbara Lipska - a leading expert on the neuroscience of mental illness - was diagnosed with melanoma that had spread to her brain. Within months, her frontal lobe, the seat of cognition, began shutting down. She descended into madness, exhibiting dementia- and schizophrenia-like symptoms that terrified her family and coworkers. But miraculously, the immunotherapy her doctors had prescribed worked quickly. Just eight weeks after her nightmare began, Lipska returned to normal. With one difference: she remembered her brush with madness with exquisite clarity.

Leaving a life marked by crippling setbacks and his father's doubt, in 1967 a 20-something doctor from India arrived in America with only five dollars and the desire to claim his American dream. Faced with an entirely new culture, racism, and the lasting effects of disabling childhood injuries, through hard work and perseverance he overcame all odds. Now having performed over 15,000 open-heart surgeries, more than nearly every surgeon in history, Dr. Singh reflects on his most memorable patients and his incredible personal life.

If there is one thing Lincee Ray has learned over the years, it's that the majority of women on the planet struggle with insecurities. Our skinny jeans mock us. Our just-trying-to-help mothers are just driving us crazy. Our social media feeds taunt us with everyone else's picture-perfect lives. It's enough to send you on a gummy-bear bender while binge-watching Friends reruns and not showering for a week. Lincee knows. She's been there. Right there, in fact. Gummy bears and all.

Here, Michael Palmer has created a cat-and-mouse game where one woman must confront a conspiracy of doctors to uncover an evil practice that touches every single person who ever has a medical test. With unforgettable characters and twists and betrayals that come from the most unlikely places, The Second Opinion will keep you guessing...and looking over your shoulder.

Hoping for the stability he needs to start a family, Sandeep Jauhar, an attending cardiologist, accepts a position at a massive teaching hospital on the outskirts of Queens. With a decade's worth of elite medical training behind him, he is eager to settle down and reap the rewards of countless sleepless nights. Instead, he is confronted with sobering truths. Doctors' morale is low and getting lower.