Dr. W. Lee Warren, a practicing brain surgeon, assumed he knew most outcomes for people with glioblastoma, head injuries, and other health-care problems. Yet even as he tried to give patients hope, his own heart would sink as he realized, I've seen the end of you. But it became far more personal when the acclaimed doctor experienced an unimaginable family tragedy. That's when he reached the end of himself. Gripping medical stories serve as the backdrop for a raw, honest look at how we can remain on solid ground when everything goes wrong.

Delia Ephron had struggled through several years of heartbreak. She’d lost her sister, Nora, and then her husband, Jerry, both to cancer. Several months after Jerry’s death, she decided to make one small change in her life - she shut down his landline, which crashed her internet. She ended up in Verizon hell.

After years of struggling in a tumultuous marriage, writer Rebecca Woolf was finally ready to leave her husband. Two weeks after telling him she wanted a divorce, he was diagnosed with stage four pancreatic cancer. Four months later, at the age of forty-four, he died. In All of This, Woolf chronicles the months before her husband’s death—and her rebirth after he was gone. With rigorous honesty and incredible awareness, she reflects on the end of her marriage: how her husband’s illness finally gave her the space to make peace with his humanity and her own.

In Shock is a riveting first-hand account from a young critical care physician, who in the passage of a moment is transfigured into a dying patient. This transposition, coincidentally timed at the end of her medical training, instantly lays bare the vast chasm between the conventional practice of medicine and the stark reality of the prostrate patient.

In 2015, Barbara Lipska - a leading expert on the neuroscience of mental illness - was diagnosed with melanoma that had spread to her brain. Within months, her frontal lobe, the seat of cognition, began shutting down. She descended into madness, exhibiting dementia- and schizophrenia-like symptoms that terrified her family and coworkers. But miraculously, the immunotherapy her doctors had prescribed worked quickly. Just eight weeks after her nightmare began, Lipska returned to normal. With one difference: she remembered her brush with madness with exquisite clarity.

Sarah Standing is a wife, a mother, a journalist, a toy shop owner, a grandmother, a great friend, a daughter, and a lover of life. She does not have the time, or inclination, to deal with cancer. But s--t happens. After a week or two of struggling to catch her breath, Sarah pops along to see her GP for a few tests. By the end of the day, she has a bag of what looks like bone broth draining from her body and is dealing with a diagnosis of non-Hodgkins lymphoma. It's cancer, says her doctor, but it's the good kind.

A powerful memoir from the Saturday Night Live cast member Cecily Strong about grieving the death of her cousin - and embracing the life-affirming lessons he taught her - amid the coronavirus pandemic.

Laurie Zaleski never aspired to run an animal rescue; that was her mother Annie’s dream. But from girlhood, Laurie was determined to make the dream come true. Thirty years later as a successful businesswoman, she did it, buying a 15-acre farm deep in the Pinelands of South Jersey. She was planning to relocate Annie and her caravan of ragtag rescues - horses and goats, dogs and cats, chickens and pigs - when Annie died, just two weeks before moving day. In her heartbreak, Laurie resolved to make her mother’s dream her own.

In this wryly humorous and innovative look at a marriage gone wrong, Hannah Pittard recalls a decade’s worth of unforgettable conversations, beginning with the one in which she discovers her husband has been having sex with her charismatic best friend, Trish. These time-jumping exchanges are fast-paced, intimate, and often jaw-dropping in their willingness to reveal the vulnerabilities inherent in any friendship or marriage.

In the tradition of books by such bestselling physician-authors as Atul Gawande, Siddhartha Mukherjee, and Danielle Ofri, this beautifully written memoir by an emergency room doctor takes place during one of his routine shifts at an urban ER. Intimately narrated as it follows the experiences of real patients, it is filled with fascinating, adrenaline-pumping scenes of rescues and deaths, and the critical, often excruciating follow-through in caring for the patients’ families.

Barbara Butcher was early in her recovery from alcoholism when she found an unexpected lifeline: a job at the Medical Examiner’s Office in New York City. The second woman ever hired for the role of Death Investigator in Manhattan, she was the first to last more than three months. The work was gritty, demanding, morbid, and sometimes dangerous—and she loved it. In What the Dead Know, she writes with the kind of New York attitude and bravado you might expect from decades in the field, investigating more than 5,500 death scenes, 680 of which were homicides.

Despite her training and years of experience as an oncology and hospice nurse, Brown finds it difficult to navigate the medical maze from the other side of the bed. Why is she so often left in the dark about procedures and treatments? Why is she expected to research her own best treatment options? Why is there so much red tape? At times she’s mad at herself for not speaking up and asking for what she needs but knows that being a “difficult” patient could mean she gets worse care.

One afternoon, Emma Nadler gets a call from her daughter's doctor that changes her life forever. Faced with the realities of raising a child with a rare genetic condition, Nadler must confront her preconceptions of motherhood and her perfectionistic beliefs. Nadler—who also happens to be a psychotherapist—offers a rare window into the unconventional ways she and her family adapt to their improbable path. Every relationship in her life—with herself, her husband, children, friends, and even clients—is reimagined as she navigates the heartbreak and hilarity of her daily life.

In 2016, Rob Delaney’s one-year-old son, Henry, was diagnosed with a brain tumor. The family had moved from Los Angeles to London with their two young boys when Rob’s wife was pregnant with Henry, their third. The move was an adventure that would bind them even more tightly together as they navigated the novelty of London, the culture clashes, and the funhouse experience of Rob’s fame—thanks to his role as co-creator and co-star of the hit series Catastrophe. Henry’s illness was a cataclysm that changed everything about their lives.

One morning in late 2017, New York Times columnist Frank Bruni woke up with strangely blurred vision. He wondered at first if some goo or gunk had worked its way into his right eye. But this was no fleeting annoyance, no fixable inconvenience.

At the age of thirty-six, on the verge of completing a decade’s worth of training as a neurosurgeon, Paul Kalanithi was diagnosed with stage IV lung cancer. One day he was a doctor treating the dying, and the next he was a patient struggling to live. And just like that, the future he and his wife had imagined evaporated.

In 2015, Barbara Lipska - a leading expert on the neuroscience of mental illness - was diagnosed with melanoma that had spread to her brain. Within months, her frontal lobe, the seat of cognition, began shutting down. She descended into madness, exhibiting dementia- and schizophrenia-like symptoms that terrified her family and coworkers. But miraculously, the immunotherapy her doctors had prescribed worked quickly. Just eight weeks after her nightmare began, Lipska returned to normal. With one difference: she remembered her brush with madness with exquisite clarity.

Professor of psychiatry Elyn R. Saks writes about her struggle with schizophrenia in this unflinching account of her mental illness. In The Center Cannot Hold, Saks draws readers into a nightmare world of medications, a misguided health-care system, and social stigmas. But she would not be defeated. With a strength and force of will that most can only imagine, Saks reclaimed her life and went on to achieve great success.

The noted research psychiatrist explores how life's disappointments and difficulties provide us with the lessons we need to become better, bigger, and more resilient human beings. Adversity is an irreducible fact of life. Although we can and should learn from all experiences, both positive and negative best-selling author Dr. Norman E. Rosenthal believes that adversity is by far the best teacher most of us will ever encounter.

Lauren Marks was 27 when an aneurysm ruptured in her brain and left her fighting for her life. She woke up in a hospital soon after with serious deficiencies to her reading, speaking, and writing abilities, and an unfamiliar diagnosis: aphasia. This would be shocking news for anyone, but Lauren was a voracious reader, an actress, director, dramaturg, and pursuing her PhD. At any other period of her life, this diagnosis would have been a devastating blow. But she woke up...different.

Benjamin Daniels is angry. He is frustrated, confused, baffled and, quite frequently, very funny. He is also a GP. These are his confessions.A woman troubled by pornographic dreams about Tom Jones. An 80-year-old man who can't remember why he's come to see the doctor.

Leaving a life marked by crippling setbacks and his father's doubt, in 1967 a 20-something doctor from India arrived in America with only five dollars and the desire to claim his American dream. Faced with an entirely new culture, racism, and the lasting effects of disabling childhood injuries, through hard work and perseverance he overcame all odds. Now having performed over 15,000 open-heart surgeries, more than nearly every surgeon in history, Dr. Singh reflects on his most memorable patients and his incredible personal life.

There’s a quiet revolution happening in the way we die. More than 1.5 million Americans a year die in hospice care - nearly 44 percent of all deaths - and a vast industry has sprung up to meet the growing demand. Once viewed as a New Age indulgence, hospice is now a $14 billion business and one of the most successful segments in health care. Changing the Way We Die, by award-winning journalists Fran Smith and Sheila Himmel, is the first book to take a broad, penetrating look at the hospice landscape.

A mesmerizing and courageous memoir: the story of two sisters uncovering the depth of their love through the life-and-death experience of a bone marrow transplant. Throughout her life Elizabeth Lesser has sought understanding about what it means to be true to yourself and, at the same time, truly connected to the ones you love. But when her sister, Maggie, needs a bone marrow transplant to save her life, and Lesser learns that she is the perfect match, she faces a far more immediate and complex question about what it really means to love.

You get ready to die the way you get ready for a trip. Start by realizing you don't know the way. Listen to a few travel guides. Study the language, look at maps, gather equipment. Let yourself imagine what it will be like. Pack your bags. This book is one of those travel guides - a guide to preparing for your own death and the deaths of people close to you. The fact of death is hard to believe. Sallie Tisdale explores our fears and all the ways death and talking about death make us uncomfortable - but she also explores its intimacies and joys.

When Amy B. Scher was struck with undiagnosed late-stage, chronic Lyme disease, the best physicians in America labeled her condition incurable and potentially terminal. Deteriorating rapidly, she went on a search to save her own life - from the top experts in Los Angeles and the world-renowned Mayo Clinic in Minneapolis to a state-of-the-art hospital in Chicago. After exhausting all of her options in the US, she discovered a possible cure - but it was highly experimental, available only in India, and had as much of a probability of killing her as it did of curing her.

In Shock is a riveting first-hand account from a young critical care physician, who in the passage of a moment is transfigured into a dying patient. This transposition, coincidentally timed at the end of her medical training, instantly lays bare the vast chasm between the conventional practice of medicine and the stark reality of the prostrate patient.

The Chopra brothers were among the most eager and ambitious of the new generation. In the 1970s, they each emigrated to the United States to make a new life. Both faced tough obstacles: while Deepak encountered resistance from Western-trained doctors over what he called the mind-body connection, Sanjiv struggled to reconcile the beliefs of his birthplace with those of his new home. Eventually, each brother became convinced that America was the right place to build a life, and the Chopras went on to great achievements.

Brainstorm follows the stories of people whose medical diagnoses are so strange even their doctor struggles to know how to solve them. A man who sees cartoon characters running across the room; a girl whose world suddenly seems completely distorted, as though she were Alice in Wonderland; another who transforms into a ragdoll whenever she even thinks about moving. The brain is the most complex structure in the universe. Neurologists must puzzle out life-changing diagnoses from the tiniest of clues, the ultimate medical detective work.

With compassion and candor, leading neurosurgeon Henry Marsh reveals the fierce joy of operating, the profoundly moving triumphs, the harrowing disasters, the haunting regrets, and the moments of black humor that characterize a brain surgeon's life. If you believe that brain surgery is a precise and exquisite craft, practiced by calm and detached surgeons, this gripping, brutally honest account will make you think again.