An epic story told by a unique voice in Ameri­can medicine, One Doctor describes life-changing experiences in the career of a distinguished physi­cian. In riveting first-person prose, Dr. Brendan Reilly takes us to the front lines of medicine today.

In Sweden, hundreds of refugee children fall into a state that resembles sleep for months or years at a time. In Le Roy, a town in upstate New York, teenage girls develop involuntary twitches and seizures that spread like a conta­gion. In the US Embassy in Cuba, employees experience headaches and memory loss after hearing strange noises during the night. These are only a few of the many sus­pected culture-bound psychosomatic syndromes - specific sets of symptoms that exist in a particular culture or environment - that affect people throughout the world.

As a Yale School of Medicine physician, the New York Times best-selling author of Every Patient Tells a Story, and an inspiration and adviser for the hit Fox TV drama, House, M.D., Lisa Sanders has seen it all. And yet, she is often confounded by the cases she describes in her column: unexpected collections of symptoms that she and other physicians struggle to diagnose. Dr. Sanders shows how making the right diagnosis requires expertise, painstaking procedure, and sometimes a little luck.

Oliver Sacks' The Man Who Mistook His Wife for a Hat tells the stories of individuals afflicted with fantastic perceptual and intellectual aberrations: patients who have lost their memories and with them the greater part of their pasts; who are no longer able to recognize people and common objects; who are stricken with violent tics and grimaces or who shout involuntary obscenities; whose limbs have become alien; who have been dismissed as retarded yet are gifted with uncanny artistic or mathematical talents.

When 24-year-old Susannah Cahalan woke up alone in a hospital room, strapped to her bed and unable to move or speak, she had no memory of how she’d gotten there. Days earlier, she had been on the threshold of a new, adult life: At the beginning of her first serious relationship and a promising career at a major New York newspaper. Now she was labeled violent, psychotic, a flight risk. What happened?

A quarter of a century after her memoir, Thinking in Pictures, forever changed how the world understood autism, Temple Grandin—the “anthropologist from Mars,” as Oliver Sacks dubbed her—transforms our awareness of the different ways our brains are wired. Do you have a keen sense of direction, a love of puzzles, the ability to assemble IKEA furniture without crying? You are likely a visual thinker.

With compassionate stories of his patients and their conditions, Dr. Leschziner illustrates the neuroscience behind our sleeping minds, revealing the many biological and psychological factors necessary in getting the rest that will not only maintain our physical and mental health, but improve our cognitive abilities and overall happiness.

Barbara Butcher was early in her recovery from alcoholism when she found an unexpected lifeline: a job at the Medical Examiner’s Office in New York City. The second woman ever hired for the role of Death Investigator in Manhattan, she was the first to last more than three months. The work was gritty, demanding, morbid, and sometimes dangerous—and she loved it. In What the Dead Know, she writes with the kind of New York attitude and bravado you might expect from decades in the field, investigating more than 5,500 death scenes, 680 of which were homicides.

In 2015, Barbara Lipska - a leading expert on the neuroscience of mental illness - was diagnosed with melanoma that had spread to her brain. Within months, her frontal lobe, the seat of cognition, began shutting down. She descended into madness, exhibiting dementia- and schizophrenia-like symptoms that terrified her family and coworkers. But miraculously, the immunotherapy her doctors had prescribed worked quickly. Just eight weeks after her nightmare began, Lipska returned to normal. With one difference: she remembered her brush with madness with exquisite clarity.

With compassion and candor, leading neurosurgeon Henry Marsh reveals the fierce joy of operating, the profoundly moving triumphs, the harrowing disasters, the haunting regrets, and the moments of black humor that characterize a brain surgeon's life. If you believe that brain surgery is a precise and exquisite craft, practiced by calm and detached surgeons, this gripping, brutally honest account will make you think again.

In Being Mortal, best-selling author Atul Gawande tackles the hardest challenge of his profession: how medicine can not only improve life but also the process of its ending. Medicine has triumphed in modern times, transforming birth, injury, and infectious disease from harrowing to manageable. But in the inevitable condition of aging and death, the goals of medicine seem too frequently to run counter to the interest of the human spirit.

How the Brain Lost Its Mind tells the rich and compelling story of two confounding ailments, syphilis and hysteria, and the extraordinary efforts to confront their effects on mental life. How does the mind work? Where does madness lie, in the brain or in the mind? How should it be treated?

The science of emotion is in the midst of a revolution on par with the discovery of relativity in physics and natural selection in biology. Leading the charge is psychologist and neuroscientist Lisa Feldman Barrett, whose research overturns the long-standing belief that emotions are automatic, universal, and hardwired in different brain regions. Instead, Barrett shows, we construct each instance of emotion through a unique interplay of brain, body, and culture.

Drawn from historical records and current news headlines, A Taste for Poison weaves together the tales of spurned lovers, shady scientists, medical professionals, and political assassins to show how the precise systems of the body can be impaired to lethal effect through the use of poison. From the deadly origins of the gin and tonic cocktail to the arsenic-laced wallpaper in Napoleon’s bedroom, A Taste for Poison leads listeners on a fascinating tour of the intricate, complex systems that keep us alive - or don’t.

On May 31, 2014, in the Milwaukee suburb of Waukesha, Wisconsin, two 12-year-old girls attempted to stab their classmate to death. Morgan Geyser and Anissa Weier’s violence was extreme, but what seemed even more frightening was that they committed their crime under the influence of a figure born by the internet: the so-called “Slenderman”. Yet the even more urgent aspect of the story, that the children involved suffered from undiagnosed mental illnesses, often went overlooked in coverage of the case.