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Basics to Brilliance: Haematology Podcast

Basics to Brilliance: Haematology Podcast

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Welcome to Basics to Brilliance, the podcast created to supplement & bolster your knowledge of Haematology.
Featuring a two way, non-didactic conversational-style Q&A between the SpR and SHO, this podcast will be your pocket companion no matter where you are.

We aim to cover:
- Malignant and non-malignant topics

- Science/lab detail

- UK guidelines, hallmark trials and how these translate into clinical practice

- Future research directions

- The whole syllabus for FRCPath part 1


All readily accessible and completely free of charge!

For every budding haematologist out there, we hope this podcast aids you in your endeavours and fills you with interest and excitement for the brilliant world of Haematology.

Warmest Regards,
Dr. Everden
Dr. Fasey
Dr. Jafri

Disclaimer: This podcast is intended as a revision aid and should not be used for the medical management of patients. Guidelines in the initial episodes span 2023/2024. We aim to update our content in accordance with the most recent available guidelines when possible.


This podcast is CPD accredited by the Royal College of Pathologists UK

© 2025 Basics to Brilliance: Haematology Podcast
Ciencia Ciencias Biológicas Enfermedades Físicas Hygiene & Healthy Living
Episodios
  • Heparin & the Anti-Xa Assay
    May 25 2025

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    00:52 Intro (shoutuout to the BSH anticoagulant monitoring guidelines)

    02:15 Practical relevance of testing and monitoring anticoagulants

    07:30 Heparin: The Basics

    09:00 Unfractionated Heparin vs. Low Molecular Weight Heparin

    10:24 Mechanism of action of Heparin (UfH vs. LMWH)

    • LMWH: more Anti-Xa activity
    • UfH Anti-IIa acitivity = Anti-Xa activity

    15:30 Pharmacokinetic differences (UfH vs. LMWH)

    23:28 Unfractionated Heparin uses and monitoring

    34:34 Anti Xa Assay

    42:32 Activated Clotting Time (POCT)

    46:56 Anti Xa in LMWH: Practical considerations

    52:03 LMWH uses and dosing

    55:30 Summary


    'Basics to Brilliance: Haematology Podcast' has been accredited for CPD credit by the Royal College of Pathologists UK.

    Medical professionals and clinical scientists holding career-grade positions, who are registered with any of the Royal Colleges for CPD, will be eligible to earn 1 credit for every hour of learning.

    Email: basicstobrilliancehaem@gmail.com

    Insta: BasicstoBrilliance

    X: @basics_2_brill

    Send us your feedback!


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    59 m
  • Thrombin Time & Fibrinogen Assays
    May 18 2025

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    00:54 Intro and table of contents

    1:48 Case 1: pre-op, prolonged PT and ++ prolonged APTT…thrombin time done

    03:44 Case 2: post-op, normal PT and prolonged APTT…thrombin time done

    04:46 Thrombin Time definition and ingredients (its all about the fibrinogen!)

    10:45 Differentiating causes of prolonged thrombin time- protamine, reptilase, ecarin

    17:24 Case 3: Major Haemorrhage (Variceal), due OGD, Derived PT Fibrinogen normal

    20:45 Clauss Fibrinogen- methodology, causes of change and treatment of deranged fibrinogen

    30:09 Derived PT Fibringoen

    31:20 ELISA, TEG and ROTEM (brief)

    33:07 Summary

    36:56 David’s request (email us your questions!)


    'Basics to Brilliance: Haematology Podcast' has been accredited for CPD credit by the Royal College of Pathologists UK.

    Medical professionals and clinical scientists holding career-grade positions, who are registered with any of the Royal Colleges for CPD, will be eligible to earn 1 credit for every hour of learning.

    Email: basicstobrilliancehaem@gmail.com

    Insta: BasicstoBrilliance

    X: @basics_2_brill

    Send us your feedback!


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    38 m
  • Mixing Studies & Factor Assays
    Apr 27 2025

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    0:52 Intro and table of contents

    2:36 CASE 1- Infection, due surgery and a prolonged APTT ft. a refresher on APTT prolongation

    08:00 Mixing studies- definition and uses ft. Hari’s exam nugget

    17:00 Factor assays (1 stage, 2 stage and chromogenic assays) ft. David’s humorous humility

    43:30 David applies his new-found knowledge to our first case

    45:45 CASE 2- Infection, hx of weight loss and bleeding and a prolonged APTT

    47:36 Summary

    https://practical-haemostasis.com/Factor%20Assays/1_stage_pt_factor_assay.html

    https://practical-haemostasis.com/Factor%20Assays/chromogenic_factor_assays.html


    'Basics to Brilliance: Haematology Podcast' has been accredited for CPD credit by the Royal College of Pathologists UK.

    Medical professionals and clinical scientists holding career-grade positions, who are registered with any of the Royal Colleges for CPD, will be eligible to earn 1 credit for every hour of learning.

    Email: basicstobrilliancehaem@gmail.com

    Insta: BasicstoBrilliance

    X: @basics_2_brill

    Send us your feedback!


    Más Menos
    52 m
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