Possible

By: Reid Hoffman
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  • Summary

  • What if, in the future, everything breaks humanity's way? Possible is an award-winning, weekly podcast that sketches out the brightest version of the future—and what it will take to get there. Hosts Reid Hoffman and Aria Finger explore what’s possible with forward-thinking leaders, deep thinkers, and ambitious builders across many fields, such as technology, art, education and healthcare. These conversations center on the ways technology—and, in particular, AI—is shaping the future. In episodes, AI tools such as OpenAI’s GPT-4 and Inflection’s Pi are at work, offering informational asides, prompting guests, or demoing what they can do. Lastly, between guest episodes, Aria interviews her co-host Reid on his latest takes on what’s possible if we use technology—and our collective effort—effectively.
    Reid Hoffman 2023
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Episodes
  • Reid riffs on Tobi’s memo, AI and play, and the tweet that cost trillions

    Reid riffs on Tobi’s memo, AI and play, and the tweet that cost trillions
    Apr 16 2025
    After Tobi Lütke, the CEO of Shopify, put out a memo stating all his employees should be expected to use AI every day, Reid offers his thoughts on AI in the workplace. He also talks about the interplay between AI, social media, mis/disinformation, and the importance of shaping technology instead of restricting technology. Plus, Reid speculates on how AI can be just as groundbreaking in the world of play as it can be in the world of work. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/
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    15 mins
  • Demis Hassabis on AI, game theory, multimodality, and the nature of creativity

    Demis Hassabis on AI, game theory, multimodality, and the nature of creativity
    Apr 9 2025
    How can AI help us understand and master deeply complex systems—from the game Go, which has 10 to the power 170 possible positions a player could pursue, or proteins, which, on average, can fold in 10 to the power 300 possible ways? This week, Reid and Aria are joined by Demis Hassabis. Demis is a British artificial intelligence researcher, co-founder, and CEO of the AI company, DeepMind. Under his leadership, DeepMind developed Alpha Go, the first AI to defeat a human world champion in Go and later created AlphaFold, which solved the 50-year-old protein folding problem. He's considered one of the most influential figures in AI. Demis, Reid, and Aria discuss game theory, medicine, multimodality, and the nature of innovation and creativity. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/ Select mentions: Hitchhiker's Guide to the Galaxy by Douglas Adams AlphaGo documentary: https://www.youtube.com/watch?v=WXuK6gekU1Y Nash equilibrium & US mathematician John Forbes Nash Homo Ludens by Johan Huizinga Veo 2, an advanced, AI-powered video creation platform from Google DeepMind The Culture series by Iain Banks Hartmut Neven, German-American computer scientist Topics: 3:11 - Hellos and intros 5:20 - Brute force vs. self-learning systems 8:24 - How a learning approach helped develop new AI systems 11:29 - AlphaGo’s Move 37 16:16 - What will the next Move 37 be? 19:42 - What makes an AI that can play the video game StarCraft impressive 22:32 - The importance of the act of play 26:24 - Data and synthetic data 28:33 - Midroll ad 28:39 - Is it important to have AI embedded in the world? 33:44 - The trade-off between thinking time and output quality 36:03 - Computer languages designed for AI 40:22 - The future of multimodality 43:27 - AI and geographic diversity 48:24 - AlphaFold and the future of medicine 51:18 - Rapid-fire Questions Possible is an award-winning podcast that sketches out the brightest version of the future—and what it will take to get there. Most of all, it asks: what if, in the future, everything breaks humanity's way? Tune in for grounded and speculative takes on how technology—and, in particular, AI—is inspiring change and transforming the future. Hosted by Reid Hoffman and Aria Finger, each episode features an interview with an ambitious builder or deep thinker on a topic, from art to geopolitics and from healthcare to education. These conversations also showcase another kind of guest: AI. Each episode seeks to enhance and advance our discussion about what humanity could possibly get right if we leverage technology—and our collective effort—effectively.
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    57 mins
  • Reid riffs on Signal, AI for cancer detection, and GPT-4o image generation

    Reid riffs on Signal, AI for cancer detection, and GPT-4o image generation
    Apr 2 2025
    In the wake of Atlantic editor-in-chief Jeffrey Goldberg’s accidental inclusion in senior government officials’ Signal group chat discussing war plans, Reid weighs in on how the U.S. government should—and shouldn’t—use encrypted messaging apps. He and Aria also discuss AI-powered breakthroughs in cancer detection and medical diagnostics, along with NVIDIA’s newly announced Superchip and OpenAI’s latest image generation capabilities. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/
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    15 mins
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