Episodes

  • From the Battlefield to the Bedside: The Past, Present, and Future of Blood Product Resuscitation with Dr. Phil Spinella -- Part 2
    Feb 24 2025

    About our Guest:

    Dr. Philip C. Spinella is a professor in the Departments of Surgery and Critical Care Medicine and the Director of the Trauma and Transfusion Medicine Research Center at the University of Pittsburgh. He also co-founded the THOR network for trauma and hemostasis research and has as been involved with multiple nationally-funded research programs.

    References:

    Use of whole blood in pediatric trauma: a narrative review - PubMed (nih.gov)

    Fresh whole blood transfusions in coalition military, foreign national, and enemy combatant patients during Operation Iraqi Freedom at a U.S. combat support hospital - PubMed (nih.gov)

    Consensus Recommendations for RBC Transfusion Practice in Critically Ill Children From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative - PubMed (nih.gov)

    Whole Blood Transfusion - PubMed (nih.gov)

    Pediatric traumatic hemorrhagic shock consensus conference recommendations - PubMed (nih.gov)

    Early Cold Stored Platelet Transfusion Following Severe Injury: A Randomized Clinical Trial - PubMed (nih.gov)

    Precision Platelet Transfusion Medicine is Needed to Improve Outcomes - PubMed (nih.gov)

    Just chill—it's worth it! (wiley.com)

    Questions, comments or feedback? Please send us a message at this link (leave email address if you would like us to relpy) Thanks! -Alice & Zac

    Support the show


    How to support PedsCrit:
    Please complete our Listener Feedback Survey
    Please rate and review on Spotify and Apple Podcasts!
    Donations are appreciated @PedsCrit on Venmo , you can also support us by becoming a patron on Patreon. 100% of funds go to supporting the show.

    Thank you for listening to this episode of PedsCrit. Please remember that all content during this episode is intended for educational and entertainment purposes only. It should not be used as medical advice. The views expressed during this episode by hosts and our guests are their own and do not reflect the official position of their institutions. If you have any comments, suggestions, or feedback-you can email us at pedscritpodcast@gmail.com. Check out http://www.pedscrit.com for detailed show notes. And visit @critpeds on twitter and @pedscrit on instagram for real time show updates.

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    43 mins
  • From the Battlefield to the Bedside: The Past, Present, and Future of Blood Product Resuscitation with Dr. Phil Spinella -- Part 1
    Feb 17 2025

    About our Guest:

    Dr. Philip C. Spinella is a professor in the Departments of Surgery and Critical Care Medicine and the Director of the Trauma and Transfusion Medicine Research Center at the University of Pittsburgh. He also co-founded the THOR network for trauma and hemostasis research, and has as been involved with multiple nationally-funded research programs.

    References:

    Use of whole blood in pediatric trauma: a narrative review - PubMed (nih.gov)

    Fresh whole blood transfusions in coalition military, foreign national, and enemy combatant patients during Operation Iraqi Freedom at a U.S. combat support hospital - PubMed (nih.gov)

    Consensus Recommendations for RBC Transfusion Practice in Critically Ill Children From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative - PubMed (nih.gov)

    Whole Blood Transfusion - PubMed (nih.gov)

    Pediatric traumatic hemorrhagic shock consensus conference recommendations - PubMed (nih.gov)

    Early Cold Stored Platelet Transfusion Following Severe Injury: A Randomized Clinical Trial - PubMed (nih.gov)

    Precision Platelet Transfusion Medicine is Needed to Improve Outcomes - PubMed (nih.gov)

    Just chill—it's worth it! (wiley.com)



    Questions, comments or feedback? Please send us a message at this link (leave email address if you would like us to relpy) Thanks! -Alice & Zac

    Support the show


    How to support PedsCrit:
    Please complete our Listener Feedback Survey
    Please rate and review on Spotify and Apple Podcasts!
    Donations are appreciated @PedsCrit on Venmo , you can also support us by becoming a patron on Patreon. 100% of funds go to supporting the show.

    Thank you for listening to this episode of PedsCrit. Please remember that all content during this episode is intended for educational and entertainment purposes only. It should not be used as medical advice. The views expressed during this episode by hosts and our guests are their own and do not reflect the official position of their institutions. If you have any comments, suggestions, or feedback-you can email us at pedscritpodcast@gmail.com. Check out http://www.pedscrit.com for detailed show notes. And visit @critpeds on twitter and @pedscrit on instagram for real time show updates.

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    40 mins
  • Gender Disparities in [Internal Medicine] Procedure Allocation with Drs. Emily Olson and Lekshmi Santhosh
    Feb 3 2025

    Article:

    Olson EM, Sanborn DM, Dyster TG, Kelm DJ, Murray SG, Santhosh L, DesJardin JT. Gender Disparities in Critical Care Procedure Training of Internal Medicine Residents. ATS Sch. 2023 Feb 13;4(2):164-176. doi: 10.34197/ats-scholar.2022-0025OC. PMID: 37538076; PMCID: PMC10394715.

    About our Guests:

    Dr. Emily Olson is a pulmonary and critical care medicine fellow at Northwestern Feinberg School of Medicine. She attended medical school at the University of Wisconsin School of Medicine and completed her internal medicine residency at Mayo Clinic in Rochester, Minnesota. In addition to her work on gender disparities in procedural training, Dr. Olson is interested in clinical feedback and transitions in medical education.

    Dr. Lekshmi Santhosh is an Associate Professor of Medicine in the Division of Pulmonary/Critical Care Medicine and the Division of Hospital Medicine at UCSF. She practices in the MICU, neuro ICU, on the Internal Medicine teaching wards, and at the Pulmonary Outpatient Faculty Practice at UCSF. Dr. Santhosh serves as the Curriculum APD for the Internal Medicine Residency and is an Associate Program Director of the Pulmonary and Critical Care Medicine Fellowship.

    Learning Objectives:

    By the end of this podcast, listeners should be able to:

    1. Define ‘mixed methods’ in a research context.
    2. Explain why a researcher might choose focus groups instead of individual interviews for qualitative assessment.
    3. Discuss factors contributing to implicit bias in procedural opportunities for trainees.
    4. Explain how implicit bias in educational opportunities might lead to a ‘leaky pipeline’ for competitive subspecialties.
    5. Identify ways to truncate their implicit bias when offering procedures to trainees.

    References:

    1. Olson EM, Sanborn DM, Dyster TG, Kelm DJ, Murray SG, Santhosh L, DesJardin JT. Gender Disparities in Critical Care Procedure Training of Internal Medicine Residents. ATS Sch. 2023 Feb 13;4(2):164-176. doi: 10.34197/ats-scholar.2022-0025OC. PMID: 37538076; PMCID: PMC10394715.
    2. Olson EM, Kennedy CC, Kelm DJ. Assessment of Gender Parity: Leadership Representation in Pulmonary and Critical Care Medicine. J Womens Health (Larchmt). 2022 Mar;31(3):439-446. doi: 10.1089/jwh.2020.8982. Epub 2021 May 5

    Questions, comments or feedback? Please send us a message at this link (leave email address if you would like us to relpy) Thanks! -Alice & Zac

    Support the show


    How to support PedsCrit:
    Please complete our Listener Feedback Survey
    Please rate and review on Spotify and Apple Podcasts!
    Donations are appreciated @PedsCrit on Venmo , you can also support us by becoming a patron on Patreon. 100% of funds go to supporting the show.

    Thank you for listening to this episode of PedsCrit. Please remember that all content during this episode is intended for educational and entertainment purposes only. It should not be used as medical advice. The views expressed during this episode by hosts and our guests are their own and do not reflect the official position of their institutions. If you have any comments, suggestions, or feedback-you can email us at pedscritpodcast@gmail.com. Check out http://www.pedscrit.com for detailed show notes. And visit @critpeds on twitter and @pedscrit on instagram for real time show updates.

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    37 mins
  • Building a Research Career with Dr. Sapna Kudchadkar -- Part 2
    Jan 13 2025

    Dr. Sapna Kudchadkar is the Anesthesiologist-in-Chief of the Johns Hopkins Children's Center and Vice Chair for Pediatric Anesthesiology and Critical Care Medicine at Johns Hopkins University School of Medicine. Dr. Kudchadkar is also the lead PI for the "PICU Up!" study, a 10-site randomized trial of a multifaceted early mobility program for critically ill children.

    In this episode, Dr. Kuchadkar shares her path from her general pediatrics residency at Hopkins to running a large multi-center trial as a dual-trained pediatric intensivist and anesthesiologist.

    Questions, comments or feedback? Please send us a message at this link (leave email address if you would like us to relpy) Thanks! -Alice & Zac

    Support the show


    How to support PedsCrit:
    Please complete our Listener Feedback Survey
    Please rate and review on Spotify and Apple Podcasts!
    Donations are appreciated @PedsCrit on Venmo , you can also support us by becoming a patron on Patreon. 100% of funds go to supporting the show.

    Thank you for listening to this episode of PedsCrit. Please remember that all content during this episode is intended for educational and entertainment purposes only. It should not be used as medical advice. The views expressed during this episode by hosts and our guests are their own and do not reflect the official position of their institutions. If you have any comments, suggestions, or feedback-you can email us at pedscritpodcast@gmail.com. Check out http://www.pedscrit.com for detailed show notes. And visit @critpeds on twitter and @pedscrit on instagram for real time show updates.

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    14 mins
  • An Expert Approach to Sedation and Early Mobility with Dr. Sapna Kudchadkar -- Part 1
    Jan 6 2025

    Dr. Sapna Kudchadkar is the Anesthesiologist-in-Chief of the Johns Hopkins Children's Center and Vice Chair for Pediatric Anesthesiology and Critical Care Medicine at Johns Hopkins University School of Medicine. She completed her training in pediatrics, pediatric intensive care, anesthesiology, and pediatric anesthesiology at Johns Hopkins Children’s Center and the Johns Hopkins Hospital, during which she also received her Ph.D. in clinical investigation at the Johns Hopkins Bloomberg School of Public Health. Dr. Kudchadkar is now the lead PI for the "PICU Up!" study, a 10-site randomized trial of a multifaceted early mobility program for critically ill children.

    Learning Objectives:

    By the end of this podcast, listeners should be able to:

    1. Discuss the best ways to prevent delirium in young children, including sedative medication selection and non-pharmacologic techniques.
    2. Describe the optimal level of sedation for a child who requires invasive mechanical ventilation for acute respiratory failure and the staffing needed to achieve this safely.
    3. Discuss how to obtain hospital resources to support early mobilization and motivate a team to accomplish these goals.

    Selected References:

    1. Traube, C., Silver, G., Gerber, L. M., Kaur, S., Mauer, E. A., Kerson, A., Joyce, C., & Greenwald, B. M. (2017). Delirium and Mortality in Critically Ill Children: Epidemiology and Outcomes of Pediatric Delirium*. Critical Care Medicine, 45(5), 891–898. https://doi.org/10.1097/CCM.0000000000002324

    2. Traube, C., Silver, G., Kearney, J., Patel, A., Atkinson, T. M., Yoon, M. J., Halpert, S., Augenstein, J., Sickles, L. E., Li, C., & Greenwald, B. (2014). Cornell Assessment of Pediatric Delirium. Critical Care Medicine, 42(3), 656–663. https://doi.org/10.1097/CCM.0b013e3182a66b76

    3. Wieczorek B, Ascenzi J, Kim Y, Lenker H, Potter C, Shata NJ, Mitchell L, Haut C, Berkowitz I, Pidcock F, Hoch J, Malamed C, Kravitz T, Kudchadkar SR. PICU Up!: Impact of a Quality Improvement Intervention to Promote Early Mobilization in Critically Ill Children. Pediatr Crit Care Med. 2016 Dec;17(12):e559-e566. doi: 10.1097/PCC.0000000000000983. PMID: 27759596; PMCID: PMC5138131.

    Questions, comments or feedback? Please send us a message at this link (leave email address if you would like us to relpy) Thanks! -Alice & Zac

    Support the show


    How to support PedsCrit:
    Please complete our Listener Feedback Survey
    Please rate and review on Spotify and Apple Podcasts!
    Donations are appreciated @PedsCrit on Venmo , you can also support us by becoming a patron on Patreon. 100% of funds go to supporting the show.

    Thank you for listening to this episode of PedsCrit. Please remember that all content during this episode is intended for educational and entertainment purposes only. It should not be used as medical advice. The views expressed during this episode by hosts and our guests are their own and do not reflect the official position of their institutions. If you have any comments, suggestions, or feedback-you can email us at pedscritpodcast@gmail.com. Check out http://www.pedscrit.com for detailed show notes. And visit @critpeds on twitter and @pedscrit on instagram for real time show updates.

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    55 mins
  • ICU Liberation with Dr. Kristina Betters & Dr. Brooke Light -- Part 2
    Dec 9 2024

    Kristina Betters, MD is an Associate Professor of Pediatrics in the division of Critical Care Medicine at Vanderbilt University and a pediatric intensivist at Monroe Carell Jr. Children’s Hospital. Dr. Betters' research interests are focused on early mobility, rehabilitation of the ICU patient, sedation, and delirium in critically ill children. She was an author of the 2022 SCCM PANDEM guidelines.

    Brooke Light, MD is a pediatric resident physician at Prisma Health in Greenville, SC. Prior to residency, she completed her MD at the Medical University of South Carolina. She is (obviously) an aspiring pediatric intensivist, and we are so happy she reached out to coordinate this episode.

    Learning Objectives:

    By the end of this podcast, listeners should be able to discuss:

    1. The rationale supporting the use of an ICU liberation bundle.
    2. Key components of the A to F ICU liberation bundle.
    3. An expert’s approach to implementing the A to F ICU liberation bundle

    References:

    1. Smith et al. 2022 Society of Critical Care Medicine Clinical Practice Guidelines on Prevention and Management of Pain, Agitation, Neuromuscular Blockade, and Delirium in Critically Ill Pediatric Patients With Consideration of the ICU Environment and Early Mobility. Pediatr Crit Care Med. 2022 Feb 1;23(2):e74-e110.
    2. Marra A, Ely EW, Pandharipande PP, Patel MB. The ABCDEF Bundle in Critical Care. Crit Care Clin. 2017 Apr;33(2):225-243.
    3. Curley et al; RESTORE Study Investigators and the Pediatric Acute Lung Injury and Sepsis Investigators Network. Protocolized sedation vs usual care in pediatric patients mechanically ventilated for acute respiratory failure: a randomized clinical trial. JAMA. 2015 Jan 27;313(4):379-89.
    4. Madden K, Wolf M, Tasker RC, Figueroa J, McCracken C, Hall M, Kamat P. Antipsychotic Drug Prescription in Pediatric Intensive Care Units: A 10-Year U.S. Retrospective Database Study. J Pediatr Intensive Care. 2021 Oct 22;13(1):46-54.

    Questions, comments or feedback? Please send us a message at this link (leave email address if you would like us to relpy) Thanks! -Alice & Zac

    Support the show


    How to support PedsCrit:
    Please complete our Listener Feedback Survey
    Please rate and review on Spotify and Apple Podcasts!
    Donations are appreciated @PedsCrit on Venmo , you can also support us by becoming a patron on Patreon. 100% of funds go to supporting the show.

    Thank you for listening to this episode of PedsCrit. Please remember that all content during this episode is intended for educational and entertainment purposes only. It should not be used as medical advice. The views expressed during this episode by hosts and our guests are their own and do not reflect the official position of their institutions. If you have any comments, suggestions, or feedback-you can email us at pedscritpodcast@gmail.com. Check out http://www.pedscrit.com for detailed show notes. And visit @critpeds on twitter and @pedscrit on instagram for real time show updates.

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    34 mins
  • ICU Liberation with Dr. Kristina Betters & Dr. Brooke Light -- Part 1
    Dec 2 2024

    Kristina Betters, MD is an Associate Professor of Pediatrics in the division of Critical Care Medicine at Vanderbilt University and a pediatric intensivist at Monroe Carell Jr. Children’s Hospital. Dr. Betters' research interests are focused on early mobility, rehabilitation of the ICU patient, sedation, and delirium in critically ill children. She was an author of the 2022 SCCM PANDEM guidelines.

    Brooke Light, MD is a pediatric resident physician at Prisma Health in Greenville, SC. Prior to residency, she completed her MD at the Medical University of South Carolina. She is (obviously) an aspiring pediatric intensivist, and we are so happy she reached out to coordinate this episode.

    Learning Objectives:

    By the end of this podcast, listeners should be able to discuss:

    1. The rationale supporting the use of an ICU liberation bundle.
    2. Key components of the A to F ICU liberation bundle.
    3. An expert’s approach to implementing the A to F ICU liberation bundle

    References:

    1. Smith et al. 2022 Society of Critical Care Medicine Clinical Practice Guidelines on Prevention and Management of Pain, Agitation, Neuromuscular Blockade, and Delirium in Critically Ill Pediatric Patients With Consideration of the ICU Environment and Early Mobility. Pediatr Crit Care Med. 2022 Feb 1;23(2):e74-e110.
    2. Marra A, Ely EW, Pandharipande PP, Patel MB. The ABCDEF Bundle in Critical Care. Crit Care Clin. 2017 Apr;33(2):225-243.
    3. Curley et al; RESTORE Study Investigators and the Pediatric Acute Lung Injury and Sepsis Investigators Network. Protocolized sedation vs usual care in pediatric patients mechanically ventilated for acute respiratory failure: a randomized clinical trial. JAMA. 2015 Jan 27;313(4):379-89.
    4. Madden K, Wolf M, Tasker RC, Figueroa J, McCracken C, Hall M, Kamat P. Antipsychotic Drug Prescription in Pediatric Intensive Care Units: A 10-Year U.S. Retrospective Database Study. J Pediatr Intensive Care. 2021 Oct 22;13(1):46-54.


    Questions, comments or feedback? Please send us a message at this link (leave email address if you would like us to relpy) Thanks! -Alice & Zac

    Support the show


    How to support PedsCrit:
    Please complete our Listener Feedback Survey
    Please rate and review on Spotify and Apple Podcasts!
    Donations are appreciated @PedsCrit on Venmo , you can also support us by becoming a patron on Patreon. 100% of funds go to supporting the show.

    Thank you for listening to this episode of PedsCrit. Please remember that all content during this episode is intended for educational and entertainment purposes only. It should not be used as medical advice. The views expressed during this episode by hosts and our guests are their own and do not reflect the official position of their institutions. If you have any comments, suggestions, or feedback-you can email us at pedscritpodcast@gmail.com. Check out http://www.pedscrit.com for detailed show notes. And visit @critpeds on twitter and @pedscrit on instagram for real time show updates.

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    31 mins
  • Hemorrhagic Shock with Dr. Matthew Borgman
    Nov 18 2024

    Matthew A. Borgman, M.D. is a Professor of Pediatrics in the Division of Pediatric Critical Care at the University of Texas Southwestern. Dr. Borgman graduated from Uniformed Services University (USU), he completed Pediatric Residency at Brooke Army Medical Center in 2007, followed by a fellowship in Critical Care at Boston Children’s Hospital. He is a prolific author in pediatric trauma management which has helped redefine the care of injured children. He is also the former national chair of the Pediatric Trauma Society Research Committee and has co-authored the 2022 Pediatric Traumatic Hemorrhagic Shock Consensus Conference Recommendations.

    Learning Objectives:

    By the end of this podcast, listeners should be able to:

    1. Define pediatric hemorrhagic shock and massive transfusion.
    2. Develop a guideline-based clinical approach to managing a child with hemorrhagic shock.
    3. Explore an expert’s approach to managing a child with hemorrhagic shock where the evidence might not be clear.


    References:

    1. Russell et al. Pediatric traumatic hemorrhagic shock consensus conference recommendations. J Trauma Acute Care Surg. 2023 Jan 1;94(1S Suppl 1):S2-S10.
    2. Spinella et al. Transfusion Ratios and Deficits in Injured Children With Life-Threatening Bleeding. Pediatr Crit Care Med. 2022 Apr 1;23(4):235-244.
    3. Gaines et al. Low Titer Group O Whole Blood In Injured Children Requiring Massive Transfusion. Ann Surg. 2023 Apr 1;277(4):e919-e924.
    4. Moore et al. Fibrinolysis Shutdown in Trauma: Historical Review and Clinical Implications. Anesth Analg. 2019 Sep;129(3):762-773.
    5. Roberts et al. The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients. Health Technol Assess. 2013 Mar;17(10):1-79.
    6. Dewan et al. CRASH-3 - tranexamic acid for the treatment of significant traumatic brain injury: study protocol for an international randomized, double-blind, placebo-controlled trial. Trials. 2012 Jun 21;13:87.
    7. Spinella et al. Survey of transfusion policies at US and Canadian children's hospitals in 2008 and 2009. Transfusion. 2010 Nov;50(11):2328-35.
    8. Whitton TP, Healy WJ. Clinical Use and Interpretation of Thromboelastography. ATS Sch. 2023 Jan 9;4(1):96-97.
    9. MATIC-2:

    Questions, comments or feedback? Please send us a message at this link (leave email address if you would like us to relpy) Thanks! -Alice & Zac

    Support the show


    How to support PedsCrit:
    Please complete our Listener Feedback Survey
    Please rate and review on Spotify and Apple Podcasts!
    Donations are appreciated @PedsCrit on Venmo , you can also support us by becoming a patron on Patreon. 100% of funds go to supporting the show.

    Thank you for listening to this episode of PedsCrit. Please remember that all content during this episode is intended for educational and entertainment purposes only. It should not be used as medical advice. The views expressed during this episode by hosts and our guests are their own and do not reflect the official position of their institutions. If you have any comments, suggestions, or feedback-you can email us at pedscritpodcast@gmail.com. Check out http://www.pedscrit.com for detailed show notes. And visit @critpeds on twitter and @pedscrit on instagram for real time show updates.

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    49 mins