A breakthrough research project has detected an active gene present in all known psychopaths and developed a vaccine to make it completely dormant. Society has rejoiced the extinction of the sociopathic mind. There hasn’t been a serial killing in America in over 40 years. Sheriff MacArthur Gray resides in the future but lives in the past. His world views have chased him from a large metropolis to his home town, but there is no sanctuary to be found after he arrives. Because people are dying and only he can see the truth. A psychopath has somehow survived and is thriving.

In a small town along the Mississippi River, separate but nearly identical attacks have left two married couples brutally murdered in their homes. A young boy—the lone survivor of the killings—now lies comatose in the hospital. And the police’s only lead is the boy’s terrified description of the assailant: a “monster."

Hidden away from the world by his famous father, Quinn Kelly strives to find meaning in his life while struggling with a deformity that has kept him from leaving the only home he has ever known. On the eve of his departure a sudden and deadly virus sweeps across the nation, killing nearly all it touches. Within days Quinn is left to fend for himself in an empty world. But there is something still very much alive beyond the walls of his sanctuary.

When novelist Andy Drake returns to his hometown to care for his ailing father, a reconnection with his childhood friend Rachel escalates into a secret love affair. For Rachel, struggling to maintain the facade of a picture-perfect life, it’s an escape from an emotionally abusive marriage. Then Andy receives an anonymous note warning him to end the affair. Or else.

It’s the house of their dreams. Former marine Harry and his wife, Sasha, have packed up their life and their golden retriever, Dash, and fled the corporate rat race to live off the land in rural Idaho. Their breathtaking new home sits on more than forty acres of meadow, aspen trees, and pine forest in the Teton Valley. Even if their friends and family think it’s a strange choice for an up-and-coming pair of urban professionals, Harry and Sasha couldn’t be happier about the future they’re building, all by their lonesome.

In the near future, a terrifying new form of dementia is affecting victims of all ages. Dr. Gillian Ryan is on the cutting edge of research and desperately determined to find a cure. She’s already lost her husband to the disease, and now her young daughter is slowly succumbing as well. After losing her funding, she is given the unique opportunity to expand her research. She will travel with a NASA team to a space station where the crew has been stricken with symptoms of a similar inexplicable psychosis—memory loss, trances, and violent, uncontrollable impulses.

Eighteen years ago, tragedy struck The Refuge cult in northern Minnesota. Forty people committed suicide, and the entire compound burned to the ground. At just 13, Clare was the sole survivor found wandering miles from the encampment, hands blistered, memories of the horrific event wiped from her mind. Now a sociology professor and liaison to the FBI specializing in cults, Clare has fought to put the past behind her. But intrusive memories and fear of inheriting her cult-leader father’s mental illness threaten to strangle Clare’s budding life when she receives a call from the past.

Family is content for Kaylee Volk. Her vlogs celebrate a happy home with her husband and their three foster children, Bethany, Mason, and Andrea. Everything is perfect until the day the family’s private plane plummets into the ocean. Only Kaylee manages to survive—with a shocking revelation: Andrea did it.

Billy Summers is a man in a room with a gun. He’s a killer for hire and the best in the business. But he’ll do the job only if the target is a truly bad guy. And now Billy wants out. But first there is one last hit. Billy is among the best snipers in the world, a decorated Iraq war vet, a Houdini when it comes to vanishing after the job is done. So what could possibly go wrong?

For nearly two decades, Jamie Warren has been running from darkness. He's haunted by a traumatic childhood and the guilt at having disappeared from his disabled brother's life. But then a series of unusual events reunites him with his estranged brother and their childhood friends, and none of them can deny the sense of fate that has seemingly drawn them back together. Nor can they deny the memories of that summer, so long ago—the strange magic taught to them by an even stranger man, and the terrible act that has followed them all into adulthood.

Michael Mace, head of security at a top-secret research facility, opens his eyes in a makeshift morgue twenty-four hours following an event in which everyone perished—including him and his best friend, Shelby Shrewsberry. Having awakened with an extraordinary ability unlike anything he—or anyone else—has ever imagined, Michael is capable of being as elusive as a ghost. He sets out to honor his late friend by helping Nina Dozier and her son, John, whom Shelby greatly admired.

As a girl, Joanna Chase thrived on Rustling Willows Ranch in Montana until tragedy upended her life. Now thirty-four and living in Santa Fe with only misty memories of the past, she begins to receive pleas—by phone, through her TV, in her dreams: I am in a dark place, Jojo. Please come and help me. Heeding the disturbing appeals, Joanna is compelled to return to Montana, and to a strange childhood companion she had long forgotten.

Quinn Quicksilver was born a mystery—abandoned at three days old on a desert highway in Arizona. Raised in an orphanage, never knowing his parents, Quinn had a happy if unexceptional life. Until the day of “strange magnetism.” It compelled him to drive out to the middle of nowhere. It helped him find a coin worth a lot of money. And it practically saved his life when two government agents showed up in the diner in pursuit of him. Now Quinn is on the run from those agents and who knows what else, fleeing for his life.

When two teenagers go missing from the small, rural town of Sallow Bend, the residents come together to search for them. Little do they suspect that finding the wayward girls will be the start of their problems. An old evil is rising, and only one man seems to realize that everyone is in danger and this is not the first time it’s happened. With the carnival in town, people want to have a good time, but for many, this will be the worst time of their lives.

It was summer in the mountains when five small children vanished from their nursery school picnic. The heat was stifling that day, the tinkle of an ice-cream van in the air.... Three-and-a-half years later, in the dead of winter, the children are returned to their families...one by one. All except for Ivy - the granddaughter of Homicide Detective Kate Wakeland. The other four children say Ivy is dead.

Hidden away from the world by his famous father, Quinn Kelly strives to find meaning in his life while struggling with a deformity that has kept him from leaving the only home he has ever known. On the eve of his departure a sudden and deadly virus sweeps across the nation, killing nearly all it touches. Within days Quinn is left to fend for himself in an empty world. But there is something still very much alive beyond the walls of his sanctuary.

Evie and her uncle Jim have just moved to an isolated cabin in a remote beach town - a far cry from their hometown of Melbourne. But Evie isn't her real name. And Jim isn't really her uncle. Jim tells Evie she did something terrible back home, that he's hiding her to protect her. But Evie can't remember anything about that night - for all she knows, he's lying. As fragments of her memory return, she starts to wonder if Jim is really her savior...or her captor.

Sixteen-year-old Sayers Wayte has everything. Popularity, good looks, perfect grades—there's nothing Sayers' family money can't buy. Until he's kidnapped by a man who tells him the privileged life he's been living is based on a lie. Trapped in a windowless room, without knowing why he's been taken or how long the man plans to keep him shut away, Sayers faces a terrifying new reality. To survive, he must forget the world he once knew, and play the part his abductor has created for him.

Following the death of his 10-year-old son, physician Peter Croft embarks on a desperate, seemingly random search for a missing child, risking his sanity, even his life in a grief-induced quest. His journey propels him into the darkest reaches of human suffering and pits him squarely against an adversary whose own obsession defies all reason.

Halcyon is the answer for all Americans who want to escape, but paradise isn't what it seems. A beautiful island in the middle of Lake Ontario - a self-sustaining community made up of people who want to live without fear, crime, or greed. Halcyon is run by Valerie Kemp, aka Mother Moon, benevolent and altruistic on the outside, but hiding an unimaginable darkness inside. She has dedicated her life to the pursuit of Glam Moon, a place of eternal beauty and healing. And she believes the pathway there can only be found at the end of pleasure.

Unbeknownst to most of humankind, a powerful network of witches thrives within the shadows of society, using their magic to keep the world in balance. But they are being eliminated - and we will all pay if their power falls... When Elyse MacAllister's great-aunt Eleanora, the woman who raised her, becomes deathly ill, Lyse puts her comfortable life in Georgia on hold to rush back to Los Angeles. And once she returns to Echo Park, Lyse discovers her great-aunt has been keeping secrets.

Paige Williams slips into her hot tub in the blackness of night - and finds herself face to face with death. Alone, terrified, fleeing a dark past, Paige must make an unthinkable choice. In Violet Dawn, hurtling events and richly drawn characters collide in a breathless story of murder, the need to belong, and faith's first glimmer. One woman's secrets unleash an entire town's pursuit, and the truth proves as elusive as the killer in their midst.

Recent World War II veteran Bull Ingram is working as muscle when a Memphis DJ hires him to find Ramblin' John Hastur. The mysterious blues man's dark, driving music - broadcast at ever-shifting frequencies by a phantom radio statio - is said to make living men insane and dead men rise. Disturbed and enraged by the bootleg recording the DJ plays for him, Ingram follows Hastur's trail into the strange, uncivilized backwoods of Arkansas, where he hears rumors the musician has sold his soul to the Devil.

When Abbey’s best friend, Kristen, vanishes at the bridge near Sleepy Hollow Cemetery, everyone else is all too quick to accept that Kristen is dead, and rumors fly that her death was no accident. Abbey goes through the motions of mourning her best friend, but privately, she refuses to believe that Kristen is really gone. Then she meets Caspian, the gorgeous and mysterious boy who shows up out of nowhere at Kristen’s funeral, and who keeps reappearing in Abbey’s life. Caspian clearly has secrets of his own, but he’s the only person who makes Abbey feel normal again.

The stillbirth of Mackenzie's son destroyed her marriage. Grieving, Mac reluctantly heads for her childhood home to seek refuge with her mother, who constantly reminds her of life's dangers. Driving across Texas, Mac swerves to avoid hitting a deer... and winds up in a dead spot, a frightening place that lies between the worlds of the living and the dead. If they can control their imaginations, people can literally bring their dreams to life - but most are besieged by fears and nightmares which pursue them relentlessly.

The Archangel of Death is the master of taking human life. But keeping mortals alive? Not exactly Azrael's forte. For thousands of years, Azrael’s greatest enemy has been silent. Leaving him in relative peace for the first time since the great angel war. Now that silence has been broken, and the Morning Star has returned with a dangerous ultimatum: Azrael can join, or watch everything he loves be destroyed. Two lives hang in the balance - Azrael’s beloved human wife, Nadine, and their unborn, part-angel son...Warren.

From the celebrated author of Swimming at Night comes a powerful and moving saga of one woman's struggle to overcome her husband's death and uncover his dark, mysterious past. Eva has only been married for eight months when her husband, Jackson, is swept to his death while fishing. Weighed down by confusion and sorrow, Eva decides to take leave of her midwifery practice in London and visit Jackson's estranged family in Tasmania with the hope of grieving together.

There are things in the darkness, things much worse than the tracks and abandoned pieces of equipment that trip the children up and gash at their feet and legs, things that brush silently past them, touching their faces before disappearing again....

Kentucky was only ever going to be a summer job. Come fall, Blue Riley would be back in North Carolina, in college. But one job led to another, one town led to another, and one woman led to another. Now, after twenty years Blue faces the hardest question of all - is it time to go home?

With tales from Laird Barron, Stephen King, John Langan, Peter Straub, and many others, and featuring Datlow’s comprehensive overview of the year in horror, now, more than ever, The Best Horror of the Year provides the petrifying horror fiction readers have come to expect - and enjoy.