When Lucy's parents are killed in a train crash, her kindly uncle steps in to look after the little girl - to the initial apprehension of his wife and her son. However, Lucy's sweet, spirited charm slowly wins over her new family, and as she overcomes the trauma of her childhood, she grows up inspired to become a doctor, just like her father. But studying medicine in London takes Lucy far from her home in Hull and the people she loves, and she has to battle to be accepted in a man's world.

Scarborough, 1880. Young Jeannie spends her days watching her mother and the other harbour girls sitting at the water's edge - mending nets, gutting herring - and waiting for her friend Ethan Wharton to come in on his father's fishing smack. As she was growing up, Jeannie always expected to marry Ethan, who is loyal and dependable. But then she meets Harry - a stranger who has come to visit from Hull for the day - and she falls for him.

Bristol 1939. At forty years of age, Mary Anne Randall still turns heads. With an abusive husband spending most of his wages on beer, she has resigned herself to be the sole breadwinner to protect her family and keep the wolves from the door. In order to make ends meet, Mary Anne runs a pawnbroking business from the wash house at the end of the garden. Following the outbreak of war an opportunity presents itself to escape her loveless marriage and find true love. Will she take that chance, or carry on living just for her children and not for herself?

Bristol, 1939. School leaver Maisie Miles suspects her father, a small-time crook, has an ulterior motive for insisting she gets a job at the W. D. & H. O. Wills tobacco factory but keeps it to herself. She's befriended by effervescent Phyllis Mason and kind-hearted Bridget Milligan who take pity on her and take Maisie under their wing. But beneath their happy-go-lucky exteriors, they all harbour dreams and worries about what the future holds.

Winter, Liverpool, 1947. Evie Kilgaren is a fighter. Abandoned by her mother and with her father long gone, she is left to raise her siblings in dockside Liverpool, as they battle against the coldest winter on record. But she is determined to make a life for herself and create a happy home for what's left of her family. Desperate for work, Evie takes a job at the Tram Tavern under the kindly watch of pub landlady and pillar of the community Connie Sharp. But Connie has problems of her own when her quiet life is upturned with the arrival of a mysterious undercover detective.

Susie did something that she knows she will always regret: giving her baby son up for adoption, to keep her infidelity secret from her family. Louise, Susie's daughter, feels the effects of that decision echoing down through the years - her mother has always been difficult, too strict with her but not strict enough with her sister, Grace, who is wild and out of control. And Danny, Susie's husband, adores her but has always sensed something wrong at the heart of their marriage.

It’s 1942, and London remains under constant threat of enemy attack as the second world war rages on. In the Bethnal Green neighborhood, Nellie Morris counts every day lucky that she emerges from the underground shelters unharmed, her loving family still surrounding her. Three years into the war, she’s grateful to hold onto remnants of normalcy—her job as assisting the mayor and nights spent at the local pub with her best friend. But after a chance encounter with Ray, an American airman stationed nearby, Nellie becomes enchanted with the idea of a broader world.

London, 1938: Lizzie Larch is a 20-year-old hat maker in London's east end. She is happy and popular, but she carries a secret. Seven years ago she was viciously attacked and recovered in a private sanatorium where she miscarried a child. Lizzie has no memory of the night of the attack, but secrets cannot stay secret for too long. When she starts courting her boss' nephew, a shocking revelation surfaces; threatening to destroy their new-found happiness.

In the autumn of 1940, four children meet on a train. Behind them is London, under heavy aerial attack; ahead of them is a ship bound for the safe shores of Canada. Arthur has promised his mother not to let his little brother, Philip, out of his sight. Pippa and Dora are on their own: polar opposites, brought together by the adventure of a lifetime. But disaster strikes mid-Atlantic, and in the chaos one of the children makes a choice that will determine the course of their lives forever.

On a leafy suburban street in Dublin, beautiful, poised Stella Greene lives with her successful husband, Matt. They're the perfect couple in every way, and Stella appears to have it all. Next door, at number 72, however, lives Rea Brady. Gruff, bad tempered and rarely seen besides the twitching of her net curtains, rumour has it she's lost it all...including her marbles, if you believe the neighbourhood gossip. But appearances can be deceiving, and when Stella and Rea's worlds collide they realise they have much in common.

Desperate to escape their stepfather’s house, sisters Amy and Lillian stow away aboard a train full of children being evacuated from London and the threat of Hitler’s bombs. Arriving in the seaside town of Worthing, they are taken in by kindly Norah and her husband, Jim. With their future now entrusted to strangers, can the girls finally find a safe harbour in these dark days of war? And will they find the strength to confront what they have been running from, when their past finally catches up with them?

Mary Doyle arrives in Dublin in 1913, doomed, she fears, to a life of domestic service. Instead, however, she finds herself deeply affected by the social and political turmoil of a fledgling nation struggling for independence. Suddenly, all that was once inevitable is no longer a certainty as she is embroiled in the very heart of the Easter Rising.

For three young boys, Liam, Patrick, and Hugo, life in Ireland of the 1960s proves to be both idyllic and flawed. Living in close proximity but leading vastly different lives, the bonds of friendship bind these young men as they grow, dream, and navigate the storms of youth.

Liverpool, 1940. When her childhood sweetheart, Johnny, is killed in action, Maxine Grey loses more than her husband - she loses her best friend. Desperate to make a difference in this awful war, Maxine takes a nursing job at London’s St Thomas’ hospital. She takes comfort in the attentions of a handsome surgeon, but Edwin Blake isn’t all he seems. And as the Blitz descends on the capital, Maxine faces more heartache. When she returns to Liverpool, she harbours a secret.

Alice Lake has arrived in London from Liverpool to start her training as a District Nurse, but her journey has been far from easy. Her parents think that she should settle down and get married, but she has already had her heart broken once and isn’t about to make the same mistake again. Alice and her best friend, Edith, are based in the East End, but before they’ve even got their smart new uniforms on, war breaks out, and Hitler’s bombs are raining down on London.