
The Ageless Brain
How to Sharpen and Protect Your Mind for a Lifetime
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Narrated by:
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Robert Petkoff
About this listen
From the bestselling author of The End of Alzheimer’s, Dr. Dale Bredesen, comes a revolutionary new approach to preventing the onset of neurodegenerative disease and creating sustained brain health.
In recent decades, advances in medicine have changed the way we think about our health. Chronic diseases like obesity, heart disease, and diabetes can be prevented or reversed. Cancer treatment has become targeted and personalized. Gene editing will allow us to eradicate many inherited disorders. But there is one class of conditions that continues to elude researchers and cause tremendous suffering: neurodegenerative disease.
More than six million Americans live with Alzheimer’s disease; by 2050, this number is projected to reach thirteen million. An additional one in ten people over the age of sixty-five have dementia, while 22 percent of older adults live with some form of cognitive impairment. And it isn’t just the elderly who are afflicted; diagnosis rates are rising in younger adults, with women at a higher risk than men. For many—especially those with a genetic predisposition—this fate has seemed inevitable. Until now.
Dr. Dale Bredesen is a pioneer in the field of neurodegenerative research. Lauded for his integrative protocol, he has, in clinical studies, reversed the symptoms of Alzheimer’s and dementia. He shared this information in his bestselling book, The End of Alzheimer’s. But Dr. Bredesen doesn’t want to only treat the symptoms of this devastating illness. He wants to prevent it from developing in the first place.
In The Ageless Brain, Dr. Bredesen will share the latest, cutting-edge science on neurodegeneration, including how misunderstandings of the disease have hindered our efforts to treat it, as well as a preventative program that listeners of all ages can put into practice to optimize their cognitive health now and sustain it for years to come. This is an audiobook for everyone who cares about their ability to stay sharp and independent for a lifetime, for those who have witnessed family members decline, and for the many listeners who are beginning to experience moments of brain fog or fatigue in middle age, and are concerned about what the future may hold.
Just as bestselling authors like Dr. Peter Attia and Dr. Michael Greger have offered essential guidance for maintaining overall health and longevity, Dr. Bredesen has written the only book you need to retain your vibrant mind—and thrive for a lifetime.
A Macmillan Audio production from Flatiron Books.
PLEASE NOTE: When you purchase this title, the accompanying PDF will be available in your Audible Library along with the audio.
©2025 Dale E. Bredesen (P)2025 Macmillan AudioListeners also enjoyed...
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Critic reviews
“For far too long, we’ve been led to believe that keeping a sharp mind and a strong memory is beyond our control. Dr. Dale Bredesen’s groundbreaking work proves otherwise. The Ageless Brain is a practical and inspiring guide that equips readers with essential knowledge to combat the most debilitating effects of aging. As a global leader in cognitive decline and brain degeneration, Dr. Bredesen gifts us with the tools and insights needed to support lifelong brain health. For everyone, this book is essential.”—David Perlmutter, MD, FACN, #1 New York Times bestselling author of Grain Brain and Drop Acid
“Dale Bredesen is at the forefront of research on cognitive decline and neurodegeneration. With The Ageless Brain, he arms readers with the essential information they need to avoid some of the most debilitating effects of aging. And it’s never too early to get started. If you have a brain—and you want to protect it—you need to read this book.”—Terry Wahls, MD, bestselling author of The Wahls Protocol
“Dr. Dale Bredesen is a world-class neuroscientist/neurologist who through his innovative and exacting research has discovered a safe and effective approach to the prevention and treatment of Alzheimer’s disease that will revolutionize the way we think about the disease.”—Jeffrey S. Bland, PhD, FACN, FACB, bestselling author of The Disease Delusion
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- By __̴ı̴̴̡̡̡ ̡͌l̡̡̡ ̡͌l̡*̡̡ ̴̡ı̴̴̡ ̡̡͡|̲̲̲͡͡͡ ̲▫̲͡ ̲̲̲͡͡π̲̲͡͡ ̲̲͡▫̲̲͡͡ ̲|̡̡̡ ̡ ̴̡ı̴̡̡ ̡͌l̡̡̡̡.___ on 04-07-25
By: BBC Studios
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Maybe You Should Talk to Someone
- A Therapist, HER Therapist, and Our Lives Revealed
- By: Lori Gottlieb
- Narrated by: Brittany Pressley
- Length: 14 hrs and 21 mins
- Unabridged
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One day, Lori Gottlieb is a therapist who helps patients in her Los Angeles practice. The next, a crisis causes her world to come crashing down. Enter Wendell, the quirky but seasoned therapist in whose office she suddenly lands. With his balding head, cardigan, and khakis, he seems to have come straight from Therapist Central Casting. Yet he will turn out to be anything but.
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It was like a hallmark movie being waterboarded into my ears for 15 hours
- By Amazon Customer on 10-01-19
By: Lori Gottlieb
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The Obesity Code
- Unlocking the Secrets of Weight Loss
- By: Dr. Jason Fung
- Narrated by: Brian Nishii
- Length: 10 hrs and 9 mins
- Unabridged
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In this highly listenable and provocative book, Dr. Jason Fung sets out an original, robust theory of obesity that provides startling insights into proper nutrition. In addition to his five basic steps - a set of lifelong habits that will improve your health and control your insulin levels - Dr. Fung explains how to use intermittent fasting to break the cycle of insulin resistance and reach a healthy weight - for good.
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There is a PDF, Folks
- By Cynthia on 06-27-17
By: Dr. Jason Fung
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The Stoic Challenge
- A Philosopher's Guide to Becoming Tougher, Calmer, and More Resilient
- By: William B. Irvine
- Narrated by: Brian Troxell
- Length: 4 hrs and 6 mins
- Unabridged
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Some people bounce back in response to setbacks; others break. We often think that these responses are hardwired, but fortunately this is not the case. Stoicism offers us an alternative approach. Plumbing the wisdom of one of the most popular and successful schools of thought from ancient Rome, philosopher William B. Irvine teaches us to turn any challenge on its head. The Stoic Challenge, then, is the ultimate guide to improving your quality of life through tactics developed by ancient Stoics, from Marcus Aurelius and Seneca to Epictetus.
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Rehashing of points in Irvine's previous work
- By Anon a Mus on 10-17-20
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The Secret to Healing Anxiety
- By: Kelly Vincent, The Great Courses
- Narrated by: Kelly Vincent
- Length: 3 hrs and 14 mins
- Original Recording
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Discover a holistic approach to mental health with The Secret to Healing Anxiety. In six compassionate and accessible lessons, clinical psychologist Dr. Kelly Vincent will teach you perspectives and strategies that can help you develop physical, emotional, and spiritual resilience.
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Excellent information
- By sparky on 01-30-25
By: Kelly Vincent, and others
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How to Train Your Mind
- Exploring the Productivity Benefits of Meditation
- By: Chris Bailey
- Narrated by: Chris Bailey
- Length: 3 hrs and 18 mins
- Original Recording
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Meditation makes you more productive because it lets you earn back time. For each minute you spend meditating, you'll earn around nine minutes back, as Chris Bailey - author of The Productivity Project and Hyperfocus - will show in this candid and counter-intuitive guide to the productivity benefits of meditation.
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Started Listening By Accident
- By T.D.Willis on 01-17-21
By: Chris Bailey
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Self Help
- This Is Your Chance to Change Your Life
- By: Gabrielle Bernstein, Richard C. Schwartz - foreword
- Narrated by: Gabrielle Bernstein, Richard C. Schwartz - foreword
- Length: 6 hrs and 1 min
- Unabridged
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Are you ready to unlock the greatest resource of your life? Gabby Bernstein has written the ultimate self-help guide, offering a revolutionary practice to radically shift your core beliefs and connect you to an infallible inner guidance system: the energy of Self within you. In this groundbreaking book, Gabby demystifies the power of Internal Family Systems (IFS) Therapy, taking its life-changing teachings out of the therapist’s office and into your everyday life.
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Self Serving
- By pricefreund on 01-14-25
By: Gabrielle Bernstein, and others
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How to Survive Menopause
- By: Samantha Bee
- Narrated by: Samantha Bee
- Length: 1 hr and 9 mins
- Original Recording
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Story
Samantha Bee wants to talk about menopause. Okay, she actually doesn’t want to, but she must. Half of the world’s population will spend one third of their lives in it, yet it’s been completely shrouded in secrecy—until now. The Emmy Award-winning host of Full Frontal with Samantha Bee shares everything she has learned in her new one-woman show, How to Survive Menopause. Because everyone needs that one best friend who will keep it real for them—like, really real.
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Authentic and powerful!
- By Tendai on 04-02-25
By: Samantha Bee
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I Thought It Was Just Me (but it isn’t)
- Telling the Truth about Perfectionism, Inadequacy, and Power
- By: Brené Brown
- Narrated by: Lauren Fortgang
- Length: 10 hrs and 44 mins
- Unabridged
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Based on seven years of ground-breaking research and hundreds of interviews, I Thought It Was Just Me shines a long-overdue light on an important truth: Our imperfections are what connect us to each other and to our humanity. Our vulnerabilities are not weaknesses; they are powerful reminders to keep our hearts and minds open to the reality that we're all in this together.
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I'm sure its great if you are a mother ....
- By Leslie A Hill on 08-09-11
By: Brené Brown
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Brain Energy
- A Revolutionary Breakthrough in Understanding Mental Health—and Improving Treatment for Anxiety, Depression, OCD, PTSD, and More
- By: Christopher M. Palmer MD
- Narrated by: Christopher M. Palmer MD
- Length: 12 hrs and 18 mins
- Unabridged
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Story
We are in the midst of a global mental health crisis, and mental illnesses are on the rise. But what causes mental illness? And why are mental health problems so hard to treat? Drawing on decades of research, Harvard psychiatrist Dr. Chris Palmer outlines a revolutionary new understanding that for the first time unites our existing knowledge about mental illness within a single framework: mental disorders are metabolic disorders of the brain. Brain Energy will transform the field of mental health, and the lives of countless people around the world.
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Arguing brain health theory to medical profession
- By Maya H Saric on 03-10-23
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The Complete Guide to Fasting
- Heal Your Body Through Intermittent, Alternate-Day, and Extended Fasting
- By: Jimmy Moore, Dr. Jason Fung
- Narrated by: Jimmy Moore
- Length: 7 hrs and 36 mins
- Unabridged
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Performance
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Thousands of books have been written about the latest and greatest diets that will help people lose weight and improve health. But a key element in any successful nutritional health program is a tried-and-true method that most people haven't thought about - yet it could be revolutionary for taking health to the next level. This ancient secret is fasting.
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Hard to get through
- By MCT on 06-03-17
By: Jimmy Moore, and others
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Should Have A PDF
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The First Survivors of Alzheimer's
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There is finally HOPE for Alzheimer's, thank God!
- By Tamra F. on 08-06-22
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The End of Alzheimer's Program
- The First Protocol to Enhance Cognition and Reverse Decline at Any Age
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In The End of Alzheimer's Dale Bredesen laid out the science behind his revolutionary new program that is the first to both prevent and reverse symptoms of Alzheimer's disease. Now he lays out the detailed program he uses with his own patients. Accessible and detailed, it can be tailored to anyone's needs and will enhance cognitive ability at any age.
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Great resource for those suffering or those caring for those suffering from Alzheimer’s or Dementia
- By Jack Aubrey on 08-18-20
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Ordinary Magic
- The Science of How We Can Achieve Big Change with Small Acts
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The emotional questions we face can define our lives. If you’re expecting an interaction to go wrong, that expectation can make it so. That’s spiraling down. But as esteemed Stanford psychologist Greg Walton shows, when we see these questions clearly, we can answer them well. Known to social psychologists as wise interventions, these shifts in perspective can help us chart new trajectories for our lives. They help us spiral up. This is ordinary magic: The ordinary experiences that help us set aside the ordinary worries of life to unleash extraordinary change.
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Reversing Alzheimer's
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A revolutionary and much-needed exploration of Alzheimer’s and how patients and their caregivers can take back control from this insidious disease. A significant portion of our population worries about the grip of dementia as we age. With over 6.5 million Americans living with Alzheimer's, the urgency for a solution has never been greater.
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Professional readers should take the time to learn to pronounce scientific terms.
- By Cowgirl on 08-30-24
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The Longevity Nutrient
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The hunt for the holy grail of healthy aging has been ongoing for hundreds of years, and Dr. Stephanie Venn-Watson may be its most unlikely champion. As a veterinary epidemiologist, she was recruited by the US Navy to lead a clinical research program to improve the health of Navy dolphins. Using advanced biotechnology to study the healthiest aging dolphins, she discovered C15:0, a saturated fat which has the potential to expand both the health-span and lifespan in long-lived mammals.
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What an amazing story!
- By GR on 04-04-25
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The End of Alzheimer's
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In this paradigm shifting book, Dale Bredesen, MD, offers real hope to anyone looking to prevent and even reverse Alzheimer's disease and cognitive decline. Revealing that AD is not one condition, as it is currently treated, but three, The End of Alzheimer's outlines 36 metabolic factors (micronutrients, hormone levels, sleep) that can trigger "downsizing" in the brain. The protocol shows us how to rebalance these factors using lifestyle modifications like taking B12, eliminating gluten, or improving oral hygiene.
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Should Have A PDF
- By IthacaNancy on 08-25-17
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The First Survivors of Alzheimer's
- How Patients Recovered Life and Hope in Their Own Words
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- Narrated by: Marc Cashman, Kimberly Farr
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It has been said that everyone knows a cancer survivor, but no one has met an Alzheimer's survivor - until now. In his first two books, Dr. Dale Bredesen outlined the revolutionary treatments that are changing what had previously seemed like the inevitable outcome of cognitive decline and dementia. And in these moving narratives, you can hear directly from the first survivors of Alzheimer’s themselves - their own amazing stories of hope told in their own words.
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There is finally HOPE for Alzheimer's, thank God!
- By Tamra F. on 08-06-22
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The End of Alzheimer's Program
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In The End of Alzheimer's Dale Bredesen laid out the science behind his revolutionary new program that is the first to both prevent and reverse symptoms of Alzheimer's disease. Now he lays out the detailed program he uses with his own patients. Accessible and detailed, it can be tailored to anyone's needs and will enhance cognitive ability at any age.
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Great resource for those suffering or those caring for those suffering from Alzheimer’s or Dementia
- By Jack Aubrey on 08-18-20
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Ordinary Magic
- The Science of How We Can Achieve Big Change with Small Acts
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The emotional questions we face can define our lives. If you’re expecting an interaction to go wrong, that expectation can make it so. That’s spiraling down. But as esteemed Stanford psychologist Greg Walton shows, when we see these questions clearly, we can answer them well. Known to social psychologists as wise interventions, these shifts in perspective can help us chart new trajectories for our lives. They help us spiral up. This is ordinary magic: The ordinary experiences that help us set aside the ordinary worries of life to unleash extraordinary change.
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Reversing Alzheimer's
- The New Toolkit to Improve Cognition and Protect Brain Health
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A revolutionary and much-needed exploration of Alzheimer’s and how patients and their caregivers can take back control from this insidious disease. A significant portion of our population worries about the grip of dementia as we age. With over 6.5 million Americans living with Alzheimer's, the urgency for a solution has never been greater.
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Professional readers should take the time to learn to pronounce scientific terms.
- By Cowgirl on 08-30-24
By: Heather Sandison
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The Longevity Nutrient
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What an amazing story!
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Keep Sharp
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Throughout our life, we look for ways to keep our minds sharp and effortlessly productive. Now, globetrotting neurosurgeon Dr. Sanjay Gupta offers “the book all of us need, young and old” (Walter Isaacson, number-one New York Times best-selling author of The Code Breaker) with insights from top scientists all over the world, whose cutting-edge research can help you heighten and protect brain function and maintain cognitive health at any age.
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A Master Class in Brain Resilience
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Good Stress
- The Health Benefits of Doing Hard Things
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Jeff Krasno, the founder and CEO of the global wellness platform Commune Media, thought he was pretty healthy. Though he suffered from brain fog, chronic fatigue, and bouts of insomnia, those symptoms seemed utterly normal in today’s society. When he learned he had diabetes, his first thought was, How can that be? I run a wellness company! His diagnosis propelled him to consult every expert at his disposal and engage in intensive “me-search” in order to turn his health around. On this journey, he began to form a larger picture of what’s wrong with our health in the modern world.
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Excellent story with a workable protocol
- By Tim Foster on 04-06-25
By: Jeff Krasno, and others
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The Alzheimer's Solution
- A Breakthrough Program to Prevent and Reverse the Symptoms of Cognitive Decline at Every Age
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Through rigorous clinical studies and research helping thousands of patients, Dean and Ayesha Sherzai - neurologists, researchers, and codirectors of the Alzheimer's Prevention Program at Cedars-Sinai Medical Center in Los Angeles - have uncovered the key lifestyle components contributing to this worldwide epidemic. They've also developed a solution - The Alzheimer's Prevention Program - to help you and your loved ones avoid developing this terrible disease and even reverse cognitive decline.
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The second book you should read...
- By Todd on 10-04-17
By: Dean Sherzai, and others
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The Stress Paradox
- Why You Need Stress to Live Longer, Healthier, and Happier
- By: Sharon Horesh Bergquist
- Narrated by: Dana Wing Lau
- Length: 7 hrs and 58 mins
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There’s a breakthrough happening in the study of wellness and longevity. We know that excessive stress can be toxic, but emerging new research reveals that too little stress is just as bad for you as too much. Dr. Sharon Bergquist, a pioneering physician and leading stress researcher, is at the forefront of this movement. In The Stress Paradox, she explains that our bodies are designed to heal and repair themselves, but we need the right amount and type of stress to rejuvenate at a cellular level.
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Real Medicine
- By Amazon Customer on 03-30-25
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The Gut-Brain Paradox
- Improve Your Mood, Clear Brain Fog, and Reverse Disease by Healing Your Microbiome
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Dr. Steven R. Gundry, the New York Times bestselling author of the groundbreaking Plant Paradox series, shares compelling evidence that our gut microbiome is driving our thoughts, feelings, behaviors, and our mental, emotional, and neuronal health—and shows us how to heal our microbiomes to take back control of our minds.
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Summary: The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline
- By: Quality Summaries
- Narrated by: David Margittai
- Length: 1 hr and 12 mins
- Unabridged
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Alzheimer’s disease is largely preventable, and often reversible. Those are bold statements, especially from a conventionally-trained neurologist. But Dale Bredesen, MD, seems to be no ordinary neurologist. After more than 30 years of intensive research into the molecular mechanisms underlying Alzheimer’s (AD), and clinical experience caring for thousands of patients, Bredesen is convinced many of medicine’s central dogmas about dementia are misguided at best, and flat-out wrong at worst.
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Loved this audio book. I am Starting to learn how to prevent Alzheimer’s in my life
- By Eric on 01-05-20
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Healing the Modern Brain
- Nine Tenets to Build Mental Fitness and Revitalize Your Mind
- By: Drew Ramsey
- Narrated by: Drew Ramsey
- Length: 7 hrs and 41 mins
- Unabridged
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The human brain—the complex organ responsible for our thoughts, feelings, and actions—has long been misunderstood. Dr. Drew Ramsey argues that to heal our brains, we must start considering conditions like depression, anxiety, ADHD and addiction—and the patients living with them—more holistically. Healing the Modern Brain offers a new approach to revitalizing and protecting mental health and achieving Mental Fitness.
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Great Insights into Mental Wellness
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By: Drew Ramsey
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Alzheimer's Disease: What If There Was a Cure? Second Edition
- The Story of Ketones
- By: Mary T. Newport MD
- Narrated by: Randye Kaye
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The story of Dr. Mary T. Newport's discovery and use of medium-chain fatty acids, which act like alternative fuel in the Alzheimer's brain, to aid her beloved husband, Steve, created such a stir when the first edition was published in 2011 that a second edition was needed to reflect the most recent developments. Dr. Newport brings the story of Steve's progress up to date and details the most recent research on a variety of topics, including possible causes of Alzheimer's and how infection, inflammation, and genetic makeup may affect an individual's response to fatty acid therapy.
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Agreed - Alzheimers needs more research.
- By Nina Jordan on 06-26-21
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The Balanced Brain
- The Science of Mental Health
- By: Camilla Nord
- Narrated by: Camilla Nord
- Length: 10 hrs and 16 mins
- Unabridged
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Overall
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Performance
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There are many routes to mental well-being. In this groundbreaking book, neuroscientist Camilla Nord offers a fascinating tour of the scientific developments that are revolutionizing the way we think about mental health, showing why and how events—and treatments—can affect people in such different ways. In The Balanced Brain, Nord explains how our brain constructs our sense of mental health—actively striving to maintain balance in response to our changing circumstances.
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Mildly informative, minimally actionable
- By Michael on 03-29-24
By: Camilla Nord
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The Shape of Things Unseen
- A New Science of Imagination
- By: Adam Zeman
- Narrated by: Ciaran Saward
- Length: 10 hrs and 59 mins
- Unabridged
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Overall
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Performance
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People often think of imagination as something used only in creative endeavours. In fact, we use imagination constantly as we reminisce, anticipate, plan, daydream, read, create imagined worlds. The truth is we live in the here and now much less than we tend to think. Imagination isn’t the exception in our daily lives; it’s our default setting. Yet only now are we beginning to understand exactly how it works. From hallucination to sleepwalking, from REM sleep to delusions, neurologist Adam Zeman brilliantly guides us through the latest scientific studies in the world of the imagination.
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One of my favorite Science Years...
- By The ghost of Mark Twain Jr. Jr. Jr. on 03-17-25
By: Adam Zeman
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Dementia Must-Knows
- The Caregiver's Guide to Early-Stage Dementia
- By: A Kraz
- Narrated by: Thomas Kincaid
- Length: 3 hrs and 13 mins
- Unabridged
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Performance
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From the seven health conditions that are often mistaken for Dementia to understanding what causes neurodegenerative disorders like Alzheimer’s, Dementia Must-Knows is the only caregiver’s guide to early-stage dementia you need.
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Give Your Loved One the Best Memories
- By Caroline on 03-06-23
By: A Kraz
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Super Agers
- By: Eric Topol
- Narrated by: Eric Topol
- Length: 14 hrs and 43 mins
- Unabridged
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Overall
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Performance
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Story
Dr. Topol’s unprecedented, evidenced-based guide is about how you and your family and friends can benefit from new treatments coming available at a faster rate than ever. From his unique position as a leader overseeing millions in research funding, Dr. Topol also explains the fundamental reasons—from semaglutides to AI—that we can be confident these breakthroughs will continue. Ninety-five percent of Americans over sixty have at least one chronic disease and almost as many have two. That is the essential problem this revolution is solving.
By: Eric Topol
What listeners say about The Ageless Brain
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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Overall
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- Candice B
- 04-03-25
Facts n studies
Details about research. Confidence of what's to come. Keeps you humble with what you have. You can start now rather than waiting for tomorrow!
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