Epigenetics is the science of living DNA, charting the chemical pathways that spur DNA into action by turning genes on and off. While the Human Genome Project of the early 2000s was hailed as the key to understanding human heredity and disease, that historic effort was just the beginning. It has taken epigenetics to fill in the picture, explaining how the fixed code of our genome is implemented in countless living processes.

The ancient Greek philosopher Aristotle called man a political animal. But what did he mean by that? What is democracy? How do democracies differ from one another? How do they stack up against their alternatives, like dictatorship? And can democracy survive the many challenges it faces today? To answer these questions, look no further than Democracy and Its Alternatives. Political science, history, and current affairs rolled into one, these 24 lectures investigate democratic government in theory and practice.

As an award-winning host of NPR’s All Things Considered, Ari Shapiro knows the power of storytelling better than most. And the longer he’s worked in the field, the more convinced he’s become of storytelling’s primal importance. In 12 fascinating lessons, this master of the craft reveals the storytelling secrets he’s learned over the course of his career as a reporter and performer, from finding a good story and choosing the right characters to conducting interviews and even delivering a story effectively out loud.

10 interview-based episodes that take ancient designs and applies them to modern lives. Your expert is Prince EA, an artist and inspirational speaker who’s spent the greater part of his career thinking about the ancient world.

Though it ended five centuries ago, the medieval era continues to permeate our world in far-reaching ways. Whether we pay attention to them or not, the influences and imprints of the Middle Ages are all around us, sometimes evident and sometimes less so. In these 36 revealing lectures, you’ll learn how to recognize the medieval impacts on the modern world, and to grasp their significance and implications. The Medieval Legacy offers you a deep look at a stunning millennium of change and innovation which continues to inform our contemporary world.

Imagine a Museum of Lost Art. If this imaginary museum contained just the artwork we knew was lost— whether from theft, purposeful destruction, vandalism, war, or the forces of nature—it would still contain more masterpieces than those in all the world’s current museums combined. Imagine that! In Lost Art: The Stories of Missing Masterpieces, art historian Noah Charney guides you through just such an imaginary museum. In 12 fascinating lectures, you will hear the stories behind the theft and/or destruction of some of the world’s most famous pieces of art.

Great powers no longer fight great wars. But how exactly did countries like the United States go from confronting powerful adversaries in 1914 and 1939 Europe to waging lengthy counterinsurgency campaigns in places like Iraq and Afghanistan? The answer lies in the profound geopolitical and technological changes that came in between.

The history of the Constitution is therefore a history of ideas that define our country and our national identity—and it’s a fascinating and revealing story. The US Constitution Through History gives you the opportunity to explore the story of this powerful document, as well as the way our interpretation of it has evolved. In 24 riveting lectures, Professor Eric Berger of the University of Nebraska takes you on a journey through America’s constitutional history. He takes you inside the minds of the Framers and unpacks the ideas that led to the break from England.

What explains the brain-body connection? How is it that something intangible like stress can really kill? How about the fact that we can and often do worry ourselves sick? And how can we take advantage of the mind’s connection to the body to reduce pain, boost physical performance, and even treat disease? Answer these questions and more in The Power of Mind over Body, a 12-lecture course that will change the way you think about physical health and the brain.

In Understanding Cognitive Biases, you will learn how to recognize biases for what they are, counteract them when necessary, and even use them to your advantage in some instances. In 24 fascinating lectures, Dr. Alexander B. Swan uses examples from psychology experiments, history, politics, movies, TV, comics, social media, and more to illustrate dozens of cognitive biases that affect us all.

In Tibet: History, Culture, and Religion, Professor Constance Kassor, will show you the real, multi-dimensional Tibet and its people who live on the “Roof of the World,” the highest and largest plateau on Earth. In 24 fascinating lectures, you will learn how Tibet’s history was shaped by kings and kingdoms, power struggles, religion, traditions, wars, peace, and the lifestyles that developed in response to living on the world’s highest plateau.

Shedding light on what creative people do, and how they do it, neuroscientists are mapping the regions of the brain that come into play during creative work, showing that creativity is a skill and something that all of us can cultivate. In these 24 compelling lectures, Professor Viskontas takes you on a deep dive into the human creative faculty. Through the many areas of knowledge within the course, Creativity and Your Brain offers empowering and inspiring guidelines for developing your own creativity.

The John F. Kennedy presidency has an indelible hold on our imaginations. Even more than half a century later, we remain captivated by the charismatic young leader who promised us the moon, who remained steadfast in the face of nuclear catastrophe, who told us to “ask not what your country can do for you, but what you can do for your country”—and whose life was cut short by shocking assassination.

Science has come a long way in solving the mysteries of the human brain, but we still have a long way to go. Understanding Disorders of the Brain is a powerful introduction to the journey of brain science in the 21st century and an excellent addition to your lifelong learning library.

Propaganda and Persuasion gives you a one-of-a-kind opportunity to explore the powerful, fascinating, and at times dangerous world of influence. Taught by Professor Dannagal G. Young of the University of Delaware, these 12 eye-opening lectures arm you with the tools of effective communication and the insight to understand—and perhaps resist—persuasion in all its forms.

Richard Dawkins' brilliant reformulation of the theory of natural selection has the rare distinction of having provoked as much excitement and interest outside the scientific community as within it. His theories have helped change the whole nature of the study of social biology, and have forced thousands to rethink their beliefs about life.

Astrophysicist Neil deGrasse Tyson has attracted one of the world’s largest online followings with his fascinating, widely accessible insights into science and our universe. Now, Tyson invites us to go behind the scenes of his public fame by unveiling his candid correspondence with people across the globe who have sought him out in search of answers. In this hand-picked collection of 100 letters, Tyson draws upon cosmic perspectives to address a vast array of questions about science, faith, philosophy, life, and of course, Pluto.

How the Earth Works takes you on an astonishing journey through time and space. In 48 lectures, you will look at what went into making our planet - from the big bang, to the formation of the solar system, to the subsequent evolution of Earth.

Hilarious, fascinating, and a roller coaster of dizzying, historical what-ifs, Napoleon's Hemorrhoids is a potpourri for serious historians and casual history buffs. In one of Phil Mason's many revelations, you'll learn that Communist jets were two minutes away from opening fire on American planes during the Cuban missile crisis, when they had to turn back as they were running out of fuel. You'll discover that before the Battle of Waterloo, Napoleon's painful hemorrhoids prevented him from mounting his horse to survey the battlefield.

Chemistry and Our Universe: How It All Works is your in-depth introduction to this vital field, taught through 60 engaging half-hour lectures that are suitable for any background or none at all. Covering a year’s worth of introductory general chemistry at the college level, plus intriguing topics that are rarely discussed in the classroom, this amazingly comprehensive course requires nothing more advanced than high-school math. Your guide is Professor Ron B. Davis, Jr., a research chemist and award-winning teacher at Georgetown University.

Welcome to the Universe is a personal guided tour of the cosmos by three of today's leading astrophysicists. Inspired by the enormously popular introductory astronomy course that Neil deGrasse Tyson, Michael A. Strauss, and J. Richard Gott taught together at Princeton, this book covers it all - from planets, stars, and galaxies to black holes, wormholes, and time travel.

From launchpad explosions to a pernicious cricket infestation to the demanding management style of Musk himself, the rise of SpaceX was beset with challenges and far from inevitable. Find out how the startup beat the odds and flew high enough to outpace their rivals... and where they're going next.

How do today's most successful tech companies - Amazon, Google, Facebook, Netflix, Tesla - design, develop, and deploy the products that have earned the love of literally billions of people around the world? Perhaps surprisingly, they do it very differently from the vast majority of tech companies. In Inspired, technology product management thought leader Marty Cagan provides listeners with a master class in how to structure and staff a vibrant and successful product organization and how to discover and deliver technology products that your customers will love.

In The Butchering Art, the historian Lindsey Fitzharris reveals the shocking world of 19th-century surgery on the eve of profound transformation. She conjures up early operating theaters - no place for the squeamish - and surgeons, working before anesthesia, who were lauded for their speed and brute strength. They were baffled by the persistent infections that kept mortality rates stubbornly high. A young, melancholy Quaker surgeon named Joseph Lister would solve the deadly riddle and change the course of history.

In this illuminating audiobook, Tyson and coauthor James Trefil, a renowned physicist and science popularizer, take on the big questions that humanity has been posing for millennia - How did life begin? What is our place in the universe? Are we alone? - and provide answers based on the most current data, observations, and theories.

Epigenetics is the science of living DNA, charting the chemical pathways that spur DNA into action by turning genes on and off. While the Human Genome Project of the early 2000s was hailed as the key to understanding human heredity and disease, that historic effort was just the beginning. It has taken epigenetics to fill in the picture, explaining how the fixed code of our genome is implemented in countless living processes.

To understand the roots of personality is to understand motivations and influences that shape behavior, which in turn reflect how you deal with the opportunities and challenges of everyday life. That's the focus of these exciting 24 lectures, in which you examine the differences in people's personalities, where these differences come from, and how they shape our lives. Drawing on information gleaned from psychology, neuroscience, and genetics, Professor Leary opens the door to understanding how personality works and why.

Science has come a long way in solving the mysteries of the human brain, but we still have a long way to go. Understanding Disorders of the Brain is a powerful introduction to the journey of brain science in the 21st century and an excellent addition to your lifelong learning library.

In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies - far from the out-of-control nightmare depicted in science fiction - have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span.

Propaganda and Persuasion gives you a one-of-a-kind opportunity to explore the powerful, fascinating, and at times dangerous world of influence. Taught by Professor Dannagal G. Young of the University of Delaware, these 12 eye-opening lectures arm you with the tools of effective communication and the insight to understand—and perhaps resist—persuasion in all its forms.

To examine the connection between the storytelling impulse and our implicit desire to understand our lives and our place in the world, you will go on a globe-spanning, time-travelling, media-traversing tour in the 12 lectures of Storytelling and the Human Condition. Your guide is award-winning journalist, author, and storyteller Alexandra Hudson, founder of Civic Renaissance, a community of lifelong learners, which she invites you to join at Civic-Renaissance.com. In this course, she will illuminate the many ways stories shape our lives throughout history and across cultures.

Nothing has had a more profound impact on the development of modern civilization than thermodynamics. Thermodynamic processes are at the heart of everything that involves heat, energy, and work, making an understanding of the subject indispensable for careers in engineering, physical science, biology, meteorology, and even nutrition and culinary arts. Get an in-depth tour of this vital and fascinating science in 24 enthralling lectures suitable for everyone from science novices to experts who wish to review elementary concepts and formulas.

Your nervous system is you. All the thoughts, perceptions, moods, passions, and dreams that make you an active, sentient being are the work of this amazing network of cells. For many centuries, people knew this was true. But no one was sure how it happened. Now, thanks to the exciting new field of neuroscience, we can chart the workings of the brain and the rest of the nervous system in remarkable detail to explain how neurons, synapses, neurotransmitters, and other biological processes produce all the experiences of everyday life, in every stage of life.

Shedding light on what creative people do, and how they do it, neuroscientists are mapping the regions of the brain that come into play during creative work, showing that creativity is a skill and something that all of us can cultivate. In these 24 compelling lectures, Professor Viskontas takes you on a deep dive into the human creative faculty. Through the many areas of knowledge within the course, Creativity and Your Brain offers empowering and inspiring guidelines for developing your own creativity.

In these 24 lectures, The Great Courses teams up with the Smithsonian’s National Zoo and Conservation Biology Institute, to take you behind the scenes of the animal world. Dr. Moore has crafted a wonderful introduction to zoology that brings you up close and personal with a breathtaking variety of animal species through the eyes of a trained zoologist.

An invisible world of astonishing complexity is all around you. A world so small you can’t see it with the naked eye. A world so crowded that its population staggers the mind. A world in which you participate every day - often without even knowing it. The inhabitants of this world are trillions of bacteria, viruses, fungi, and other organisms, collectively known as microbes. Hundreds of thousands could fit on the period at the end of this sentence. And many play a powerful role in your life.

The issues addressed by macroeconomics are all around you, all the time—from taxes to inflation to mention of the GDP on the nightly news. By learning the principles of macroeconomics, you’ll be able to go beyond simply hearing the terms to better understanding their relationships to each other and how they create the economic environment in which you live. In fact, macroeconomics with its “big-picture glasses” allows you to better ask—and better try to answer—the biggest questions of our time, questions that impact the lives of billions of people.

Great powers no longer fight great wars. But how exactly did countries like the United States go from confronting powerful adversaries in 1914 and 1939 Europe to waging lengthy counterinsurgency campaigns in places like Iraq and Afghanistan? The answer lies in the profound geopolitical and technological changes that came in between.

Do you ever wish you could just get rid of all of your problems? Research shows that we grow into our best and most joyful selves not when we avoid our problems but when we embrace them, confident that we are resilient enough to work through them to an appropriate resolution. Resilience is our ability to physically, emotionally, and mentally bounce back from adverse circumstances. In fact, our capacity to thrive in life depends directly our resilience.

Rachel Pacheco, professor of management at Georgetown University’s McDonough Business School and a former chief people officer, will give you tools and tips that will immediately and positively affect how you manage people, despite differences in communication styles or personalities. With seven research-backed lessons, including suggested exercises, this course will help you develop and practice the skills to ultimately make you more fulfilled, competent, and successful in your role.