In a world where UFO sightings have become alarmingly frequent, the US government's top-secret A.L.I.V.E. Project was created to prepare for an impending alien threat. Dr. Maeve Leander, raised in the shadow of this covert operation, now leads the research on Alvie, the project's first alien subject. To Maeve, Alvie isn't just an experiment; he's family. But when a mysterious new agency seizes control of A.L.I.V.E., Maeve's world is turned upside down.

When the research starship Galileo vanishes without a trace, the powers-that-be are quick to bury the incident, eager to prevent escalating tensions that could lead to war. As a former POW, Soren refuses to give the ship up for lost. His daughter is one of the missing. Taking matters into his own hands, Soren starts pulling strings and calling in favors, determined to launch a clandestine mission to bring Galileo home. When an old friend offers him a ship for the operation, he expects a rusty relic headed for the scrapyard.

For the first time in centuries, a child was born without a superpower. Eighteen-year-old Carson Adachi has lived his entire life believing that he was indeed Powerless. During Recruitment for trade schools, Carson’s power begins to manifest and he learns that there are far worse things to be than powerless. The leaders of the known world – the Council – take an interest in Carson and his unique power, but tensions quickly rise as he questions the knowledge of his rulers.

In a society where bionic enhancements are the epitome of wealth and power, scientific researcher Dr Rosio Arata threatens to topple the status quo with her pioneering organic enhancements. Yet when a horrific accident kills her daughter, Ro's quest for answers leads her to becoming trapped in a twisted version of her life's work. In a bleak underground colony, sixteen year-old Ever is primed to rise through the ranks, gain selection and become a Saviour.

Jennifer Plummer and the Divine Flesh have exactly three things in common: They're trapped inside Jennifer's body, they despise each other, and they're in love with Daryl Plummer, Jennifer's ex-husband.