A gripping journey of discovery, The Catalyst moves from the early experiments that first hinted at RNA's spectacular powers, to Cech's own paradigm-shifting finding that it can catalyze cellular reactions, to the cutting-edge biotechnologies poised to reshape our health.

At its simplest, Bayes’s theorem describes the probability of an event, based on prior knowledge of conditions that might be related to the event. But in Everything Is Predictable, Tom Chivers lays out how it affects every aspect of our lives. He explains why highly accurate screening tests can lead to false positives and how a failure to account for it in court has put innocent people in jail. A cornerstone of rational thought, many argue that Bayes’s theorem is a description of almost everything. But who was the man who lent his name to this theorem?

In How the World Made the West, Josephine Quinn poses perhaps the most significant challenge ever to the “civilizational thinking” regarding the origins of Western culture—that is, the idea that civilizations arose separately and distinctly from one another. Rather, she locates the roots of the modern West in everything from the law codes of Babylon, Assyrian irrigation, and the Phoenician art of sail to Indian literature, Arabic scholarship, and the metalworking riders of the Steppe, to name just a few examples.

In the developed world, we’ve reaped the benefits of refrigeration for more than a century, but the costs are catching up with us. We’ve eroded our connection to our food and redefined what “fresh” means. More important, refrigeration is one of the leading contributors to climate change. As the developing world races to build a US-style cold chain, Twilley asks: Can we reduce our dependence on refrigeration? Should we?

Trigonometry is perhaps the most essential concept humans have ever devised. The simple yet versatile triangle allows us to record music, map the world, launch rockets into space, and be slightly less bad at pool. Triangles underpin our day-to-day lives and civilization as we know it. In Love Triangle, Matt Parker argues we should all show a lot more love for triangles, along with all the useful trigonometry and geometry they enable.

In the bestselling The Signal and the Noise, Nate Silver showed how forecasting would define the age of Big Data. Now, in this timely and riveting new book, Silver investigates "The River," or those whose mastery of risk allows them to shape—and dominate—so much of modern life. These professional risk takers—poker players and hedge fund managers, crypto true-believers and blue-chip art collectors—can teach us much about navigating the uncertainty of the 21st century.

In this vivid and alluring history, medievalist Anthony Bale invites listeners on an odyssey across the medieval world. Journeying alongside scholars, spies, and saints, from Western Europe to the Far East, the Antipodes and the ends of the earth, Bale provides indispensable information on the exchange rate between Bohemian ducats and Venetian groats, medieval cures for seasickness, and how to avoid extortionist tour guides and singing sirens.

We tend to think of the Middle Ages as a dark, backward, and unchanging time characterized by violence, ignorance, and superstition. By contrast, we believe progress arose from science and technological innovation, and that inventions of recent centuries created the modern world. We couldn't be more wrong.

Books about the origins of humanity dominate bestseller lists, while national newspapers present breathless accounts of new archaeological findings and speculate about what those findings tell us about our earliest ancestors. We are obsessed with prehistory—and, in this respect, our current era is no different from any other in the last three hundred years. In this coruscating work, acclaimed historian Stefanos Geroulanos demonstrates how claims about the earliest humans not only shaped Western intellectual culture, but gave rise to our modern world.

The breakthrough concepts of Pattern Breakers come from the observations of Mike Maples Jr., a seasoned venture capitalist, who noticed something strange. Start-ups like Twitter, Twitch, and Lyft had achieved extraordinary success despite their disregard for “best practices.” In contrast, other startups deemed highly promising often failed, even when they seemed to do everything right. Seeking answers, Maples and coauthor Peter Ziebelman set out to discover the hidden forces that drive extraordinary start-up success.

The knowledge of death is so terrifying that we live most of our lives in denial of it. One of the most difficult moments of childhood must be when each of us first realizes that not only we but all our loved ones will die—and there is nothing we can do about it. Or at least, there hasn’t been. Today, we are living through a revolution in biology. Giant strides are being made in understanding why we age—and why some species live longer than others. Could we eventually cheat disease and death and live for a very long time, possibly many times our current lifespan?

How a band of antislavery leaders recovered the radical philosophical inspirations of the first American Revolution to defeat the slaveholders' oligarchy in the Civil War.

In April 1942, the Imperial Japanese Army steamrolled through Burma, capturing the only ground route from India to China. Supplies to this critical zone would now have to come from India by air—meaning across the Himalayas, on the most hazardous air route in the world. SKIES OF THUNDER is a story of an epic human endeavor, in which Allied troops faced the monumental challenge of operating from airfields hacked from the jungle, and took on “the Hump,” the fearsome mountain barrier that defined the air route.

From the Pulitzer-prize winning, New York Times bestselling author, an alarming account of how autocracies work together to undermine the democratic world, and how we should organize to defeat them.

From the creation of the first encyclopedia to Wikipedia, from ancient museums to modern kindergarten classes—this is Simon Winchester’s brilliant and all-encompassing look at how humans acquire, retain, and pass on information and data, and how technology continues to change our lives and our minds. Throughout this fascinating tour, Winchester forces us to ponder what rational humans are becoming. What good is all this knowledge if it leads to lack of thought? What is information without wisdom?

Astrophysicist Neil deGrasse Tyson has attracted one of the world’s largest online followings with his fascinating, widely accessible insights into science and our universe. Now, Tyson invites us to go behind the scenes of his public fame by unveiling his candid correspondence with people across the globe who have sought him out in search of answers. In this hand-picked collection of 100 letters, Tyson draws upon cosmic perspectives to address a vast array of questions about science, faith, philosophy, life, and of course, Pluto.

Richard Dawkins' brilliant reformulation of the theory of natural selection has the rare distinction of having provoked as much excitement and interest outside the scientific community as within it. His theories have helped change the whole nature of the study of social biology, and have forced thousands to rethink their beliefs about life.

How the Earth Works takes you on an astonishing journey through time and space. In 48 lectures, you will look at what went into making our planet - from the big bang, to the formation of the solar system, to the subsequent evolution of Earth.

Hilarious, fascinating, and a roller coaster of dizzying, historical what-ifs, Napoleon's Hemorrhoids is a potpourri for serious historians and casual history buffs. In one of Phil Mason's many revelations, you'll learn that Communist jets were two minutes away from opening fire on American planes during the Cuban missile crisis, when they had to turn back as they were running out of fuel. You'll discover that before the Battle of Waterloo, Napoleon's painful hemorrhoids prevented him from mounting his horse to survey the battlefield.

Welcome to the Universe is a personal guided tour of the cosmos by three of today's leading astrophysicists. Inspired by the enormously popular introductory astronomy course that Neil deGrasse Tyson, Michael A. Strauss, and J. Richard Gott taught together at Princeton, this book covers it all - from planets, stars, and galaxies to black holes, wormholes, and time travel.

We are in the midst of a global mental health crisis, and mental illnesses are on the rise. But what causes mental illness? And why are mental health problems so hard to treat? Drawing on decades of research, Harvard psychiatrist Dr. Chris Palmer outlines a revolutionary new understanding that for the first time unites our existing knowledge about mental illness within a single framework: mental disorders are metabolic disorders of the brain. Brain Energy will transform the field of mental health, and the lives of countless people around the world.

How do today's most successful tech companies - Amazon, Google, Facebook, Netflix, Tesla - design, develop, and deploy the products that have earned the love of literally billions of people around the world? Perhaps surprisingly, they do it very differently from the vast majority of tech companies. In Inspired, technology product management thought leader Marty Cagan provides listeners with a master class in how to structure and staff a vibrant and successful product organization and how to discover and deliver technology products that your customers will love.

In this illuminating audiobook, Tyson and coauthor James Trefil, a renowned physicist and science popularizer, take on the big questions that humanity has been posing for millennia - How did life begin? What is our place in the universe? Are we alone? - and provide answers based on the most current data, observations, and theories.

From launchpad explosions to a pernicious cricket infestation to the demanding management style of Musk himself, the rise of SpaceX was beset with challenges and far from inevitable. Find out how the startup beat the odds and flew high enough to outpace their rivals... and where they're going next.

The real stories behind the scenery of America’s national parks. For 12 years, Andrea Lankford lived in the biggest, most impressive national parks in the world, working a job she loved. She chaperoned baby sea turtles on their journey to sea. She pursued bad guys on her galloping patrol horse. She jumped into rescue helicopters bound for the heart of the Grand Canyon. She won arguments with bears. She slept with a few too many rattlesnakes. Hell yeah, it was the best job in the world! Fortunately, Andrea survived it.

We are living in a golden age in astronomy and in the search for life the universe. Over the last few decades, space exploration has shown that not only are there habitable environments within our solar system, but there are millions of exoplanets within our galaxy that could support life. We are on the cusp of breakthroughs that will revolutionize our understanding of our place in the cosmos in. In The Secret Life of the Universe, astrobiologist and the director of the Carl Sagan Center at the SETI Institute Nathalie A. Cabrol takes us to the frontiers of the search for life.

In this visionary book, Leslie Valiant argues that understanding the nature of our own educability is crucial to safeguarding our future. After breaking down how we process information to learn and apply knowledge, and drawing comparisons with other animals and AI systems, he explains why education should be humankind's central preoccupation. Will the unique capability that has been so foundational to our achievements and civilization continue to drive our progress, or will we fall victim to our vulnerabilities?

Math has a reputation for being inaccessible. People think that it requires a special gift or that comprehension is a matter of genes. Yet, the greatest mathematicians throughout history, from Rene Descartes to Alexander Grothendieck, have insisted that this is not the case.

Money laundering has been around for centuries. For as long as people have been stealing money, there's been an industry ready to wash it. But recent tech innovations have created vastly complex new systems for laundering that threaten to overwhelm authorities, destabilise economies and disrupt societies. Ranging from the flamboyant luxury of Dubai hotels to quiet coastal Ireland, from the UK to Nigeria and from Indonesia to North Korea, Rinsed is a truly global relevatory investigation into the new army of innovative launderers ... and the consequences for all of us.

This book reveals how statistics and probability are fundamental to our everyday lives—from advertisements to public opinion polls, weather forecasts to government policies, scientific research to stock market information. Haim Shapira then presents a myriad of anecdotes, riddles, case studies and practical exercises in his trademark witty voice to guide the listner through the importance of statistics and probability in everyday life.

Join sensational drag queen Kyne Santos on an extraordinary journey through the glamorous world of…math? This sassy book is your VIP pass, taking you behind the scenes with a TikTok superstar who shatters stereotypes and proves that math can be fascinating and fun, even for people who think they aren’t good at it.

In The Language Puzzle, renowned archaeologist Steven Mithen puts forward a groundbreaking new account of the origins of language. Scientists have gained new insights into the first humans of 2.8 million years ago, and how numerous species flourished but only one, Homo sapiens, survives today. Drawing from this work and synthesizing research across archaeology, psychology, linguistics, genetics, and more, Mithen details a step-by-step explanation of how our human ancestors transitioned from apelike calls to words, and from words to language as we use it today.

We are living through a revolution in machine learning-powered AI that shows no signs of slowing down. This technology is based on relatively simple mathematical ideas, some of which go back centuries, including linear algebra and calculus, the stuff of seventeenth- and eighteenth-century mathematics. It took the birth and advancement of computer science and the kindling of 1990s computer chips designed for video games to ignite the explosion of AI that we see today. In this enlightening book, Anil Ananthaswamy explains the fundamental math behind machine learning.

It’s comforting to think that we can be successful because we work hard, climb ladders, and get what we deserve, but each of us has been profoundly touched by randomness. Chance is shown to play a crucial role in shaping outcomes across history, throughout the natural world, and in our everyday lives. In The Random Factor, Mark Robert Rank draws from a wealth of evidence, including interviews and research, to explain how luck and chance play out and reveals how we can use these lessons to guide our personal lives and public policies.

Bea couldn't be more excited to trade the stifling Stockholm summer heat for vacation on Gotland Island. She’s looking forward to spending quality time with her beloved husband of thirty-two years, Niklas, and their two moody teenage daughters, and recuperating from the stress of daily life in the company of her beloved in-laws. One night shortly before their departure, Bea and Niklas have a seemingly mundane argument over a trivial issue, and Niklas goes out with a friend to blow off steam.

Science writer Sadie Dingfelder has always known that she’s a little quirky. But while she’s made some strange mistakes over the years, it’s not until she accosts a stranger in a grocery store (whom she thinks is her husband) that she realizes something is amiss. With a mixture of curiosity and dread, Dingfelder starts contacting neuroscientists and lands herself in scores of studies. In the course of her nerdy midlife crisis, she discovers that she is emphatically not neurotypical.

If the history of the Earth were compressed down to a year, our species would arise in the last thirty minutes or so of the final hour. But life itself is not such a late arrival: It has existed on Earth for something like 3.7 billion years—most of our planet’s history and over a quarter of the age of the universe (as far as we can tell). What have these organisms—bacteria, animals, plants, and the rest—done in all this time? In Living on Earth, the philosopher Peter Godfrey-Smith proposes a new way of understanding how the actions of living beings have shaped our planet.

Meet the Lazarus Group, a shadowy cabal of hackers accused of working on behalf of the North Korean state. It's claimed that they form one of the most dangerous criminal enterprises on the planet, having stolen more than $1bn in an international crime spree. Their targets allegedly include central banks, Hollywood film studios and even the British National Health Service. North Korea denies the allegations, saying the accusations are American attempts to tarnish its image.

When Mary McLeod Bethune died, tributes in newspapers around the country said the same thing: she should be on the Mount Rushmore of Black American achievement. Indeed, Bethune is the only Black American whose statue stands in the rotunda of the US Capitol, and yet for most, she remains a marble figure from the dim past. Now, seventy years later, Noliwe Rooks turns Bethune from stone to flesh, showing her to have been a visionary leader with lessons to still teach us as we continue on our journey toward a freer and more just nation.

At its simplest, Bayes’s theorem describes the probability of an event, based on prior knowledge of conditions that might be related to the event. But in Everything Is Predictable, Tom Chivers lays out how it affects every aspect of our lives. He explains why highly accurate screening tests can lead to false positives and how a failure to account for it in court has put innocent people in jail. A cornerstone of rational thought, many argue that Bayes’s theorem is a description of almost everything. But who was the man who lent his name to this theorem?