
Living Medicine
Don Thomas, Marrow Transplantation, and the Cell Therapy Revolution
Failed to add items
Add to Cart failed.
Add to Wish List failed.
Remove from wishlist failed.
Adding to library failed
Follow podcast failed
Unfollow podcast failed
$0.99/mo for the first 3 months

Buy for $19.26
No default payment method selected.
We are sorry. We are not allowed to sell this product with the selected payment method
-
Narrated by:
-
Nathan Agin
About this listen
A sweeping biography of the visionary behind bone marrow transplantation and the story of the diseases cured by Don Thomas's discovery.
In the last half of the twentieth century, Thomas himself discovered a cure for every marrow-based disease—like leukemia, lymphoma, and sickle-cell anemia—forever changing treatment for some of the deadliest illnesses. His feats were extraordinary, earning him a Nobel Prize, and the cascade of treatments he inspired have reshaped and will continue to reshape the practice of clinical medicine. Yet no one has ever written Thomas’s courageous story. Dr. Frederick R. Appelbaum, a member of Thomas’s research team, does so for the first time in Living Medicine: Don Thomas, Marrow Transplantation, and the Cell Therapy Revolution.
Bone marrow transplantation has now saved over a million lives, but when Thomas first had the idea, he was met with disbelief by the scientific community. Appelbaum, informed by decades in the field and personal connection with Thomas, tells us the secrets to Thomas’s success: his unique characteristics, how he created an effective team of researchers, and how he overcame the technical obstacles of marrow transplantation. Appelbaum tells a bigger story, too, of the scientific and societal implications of this achievement, which are critical for scientific and lay listeners alike so that we all might be better informed of how far our medical progress has come and will go.
©2023 Fred Appelbaum (P)2023 Mayo Clinic PressListeners also enjoyed...
-
Going Infinite
- The Rise and Fall of a New Tycoon
- By: Michael Lewis
- Narrated by: Michael Lewis
- Length: 9 hrs and 35 mins
- Unabridged
-
Overall
-
Performance
-
Story
When Michael Lewis first met him, Sam Bankman-Fried was the world’s youngest billionaire and crypto’s Gatsby. CEOs, celebrities, and leaders of small countries all vied for his time and cash after he catapulted, practically overnight, onto the Forbes billionaire list. Who was this rumpled guy in cargo shorts and limp white socks, whose eyes twitched across Zoom meetings as he played video games on the side?
-
-
really expected more rigor from Michael Lewis
- By Wowhello on 10-04-23
By: Michael Lewis
-
The Emperor of All Maladies
- A Biography of Cancer
- By: Siddhartha Mukherjee
- Narrated by: Fred Sanders
- Length: 22 hrs and 18 mins
- Unabridged
-
Overall
-
Performance
-
Story
The Emperor of All Maladies reveals the many faces of an iconic, shape-shifting disease that is the defining plague of our generation. The story of cancer is a story of human ingenuity, resilience, and perseverance but also of hubris, arrogance, paternalism, and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer".
-
-
Incredible
- By S.R.E. on 03-02-16
-
The Gene
- An Intimate History
- By: Siddhartha Mukherjee
- Narrated by: Dennis Boutsikaris
- Length: 19 hrs and 22 mins
- Unabridged
-
Overall
-
Performance
-
Story
The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.
-
-
It's a Wonderful Book
- By JKC on 06-02-16
-
Elon Musk
- By: Walter Isaacson
- Narrated by: Jeremy Bobb, Walter Isaacson
- Length: 20 hrs and 39 mins
- Unabridged
-
Overall
-
Performance
-
Story
When Elon Musk was a kid in South Africa, he was regularly beaten by bullies. One day a group pushed him down some concrete steps and kicked him until his face was a swollen ball of flesh. He was in the hospital for a week. But the physical scars were minor compared to the emotional ones inflicted by his father, an engineer, rogue, and charismatic fantasist.
-
-
megalomania on display
- By JP on 09-12-23
By: Walter Isaacson
-
Determined
- A Science of Life Without Free Will
- By: Robert M. Sapolsky
- Narrated by: Kaleo Griffith
- Length: 13 hrs and 42 mins
- Unabridged
-
Overall
-
Performance
-
Story
Robert Sapolsky’s Behave, his now classic account of why humans do good and why they do bad, pointed toward an unsettling conclusion: We may not grasp the precise marriage of nature and nurture that creates the physics and chemistry at the base of human behavior, but that doesn’t mean it doesn’t exist. Now, in Determined, Sapolsky takes his argument all the way, mounting a brilliant (and in his inimitable way, delightful) full-frontal assault on the pleasant fantasy that there is some separate self telling our biology what to do.
-
-
Abridged - no Appendix!
- By Amazon Customer on 11-02-23
-
For Blood and Money
- Billionaires, Biotech, and the Quest for a Blockbuster Drug
- By: Nathan Vardi
- Narrated by: Rob Shapiro
- Length: 8 hrs and 33 mins
- Unabridged
-
Overall
-
Performance
-
Story
For Blood and Money tells the little-known story of how an upstart biotechnology company created a one-in-a-million cancer drug and how the core team—denied their share of the profits—went and did it again. In this epic saga of money and science, veteran financial journalist Nathan Vardi explains how the invention of two of the biggest cancer drugs in history became (for their backers) two of the greatest Wall Street bets of all time.
-
-
Must-read for biotech enthusiasts and scientists
- By Anonymous User on 03-16-23
By: Nathan Vardi
-
Going Infinite
- The Rise and Fall of a New Tycoon
- By: Michael Lewis
- Narrated by: Michael Lewis
- Length: 9 hrs and 35 mins
- Unabridged
-
Overall
-
Performance
-
Story
When Michael Lewis first met him, Sam Bankman-Fried was the world’s youngest billionaire and crypto’s Gatsby. CEOs, celebrities, and leaders of small countries all vied for his time and cash after he catapulted, practically overnight, onto the Forbes billionaire list. Who was this rumpled guy in cargo shorts and limp white socks, whose eyes twitched across Zoom meetings as he played video games on the side?
-
-
really expected more rigor from Michael Lewis
- By Wowhello on 10-04-23
By: Michael Lewis
-
The Emperor of All Maladies
- A Biography of Cancer
- By: Siddhartha Mukherjee
- Narrated by: Fred Sanders
- Length: 22 hrs and 18 mins
- Unabridged
-
Overall
-
Performance
-
Story
The Emperor of All Maladies reveals the many faces of an iconic, shape-shifting disease that is the defining plague of our generation. The story of cancer is a story of human ingenuity, resilience, and perseverance but also of hubris, arrogance, paternalism, and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer".
-
-
Incredible
- By S.R.E. on 03-02-16
-
The Gene
- An Intimate History
- By: Siddhartha Mukherjee
- Narrated by: Dennis Boutsikaris
- Length: 19 hrs and 22 mins
- Unabridged
-
Overall
-
Performance
-
Story
The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.
-
-
It's a Wonderful Book
- By JKC on 06-02-16
-
Elon Musk
- By: Walter Isaacson
- Narrated by: Jeremy Bobb, Walter Isaacson
- Length: 20 hrs and 39 mins
- Unabridged
-
Overall
-
Performance
-
Story
When Elon Musk was a kid in South Africa, he was regularly beaten by bullies. One day a group pushed him down some concrete steps and kicked him until his face was a swollen ball of flesh. He was in the hospital for a week. But the physical scars were minor compared to the emotional ones inflicted by his father, an engineer, rogue, and charismatic fantasist.
-
-
megalomania on display
- By JP on 09-12-23
By: Walter Isaacson
-
Determined
- A Science of Life Without Free Will
- By: Robert M. Sapolsky
- Narrated by: Kaleo Griffith
- Length: 13 hrs and 42 mins
- Unabridged
-
Overall
-
Performance
-
Story
Robert Sapolsky’s Behave, his now classic account of why humans do good and why they do bad, pointed toward an unsettling conclusion: We may not grasp the precise marriage of nature and nurture that creates the physics and chemistry at the base of human behavior, but that doesn’t mean it doesn’t exist. Now, in Determined, Sapolsky takes his argument all the way, mounting a brilliant (and in his inimitable way, delightful) full-frontal assault on the pleasant fantasy that there is some separate self telling our biology what to do.
-
-
Abridged - no Appendix!
- By Amazon Customer on 11-02-23
-
For Blood and Money
- Billionaires, Biotech, and the Quest for a Blockbuster Drug
- By: Nathan Vardi
- Narrated by: Rob Shapiro
- Length: 8 hrs and 33 mins
- Unabridged
-
Overall
-
Performance
-
Story
For Blood and Money tells the little-known story of how an upstart biotechnology company created a one-in-a-million cancer drug and how the core team—denied their share of the profits—went and did it again. In this epic saga of money and science, veteran financial journalist Nathan Vardi explains how the invention of two of the biggest cancer drugs in history became (for their backers) two of the greatest Wall Street bets of all time.
-
-
Must-read for biotech enthusiasts and scientists
- By Anonymous User on 03-16-23
By: Nathan Vardi
-
The Song of the Cell
- An Exploration of Medicine and the New Human
- By: Siddhartha Mukherjee
- Narrated by: Dennis Boutsikaris
- Length: 16 hrs and 3 mins
- Unabridged
-
Overall
-
Performance
-
Story
From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.
-
-
Beyond Words Wonderful
- By Lynn on 11-27-22
-
Quiet
- The Power of Introverts in a World That Can't Stop Talking
- By: Susan Cain
- Narrated by: Kathe Mazur
- Length: 10 hrs and 39 mins
- Unabridged
-
Overall
-
Performance
-
Story
At least one-third of the people we know are introverts. They are the ones who prefer listening to speaking; who innovate and create but dislike self-promotion; who favor working on their own over working in teams. It is to introverts—Rosa Parks, Chopin, Dr. Seuss, Steve Wozniak—that we owe many of the great contributions to society.
-
-
Thought provoking and Uplifting.... A++++++++!!!!!
- By Theodore on 03-12-12
By: Susan Cain
-
Outlive
- The Science and Art of Longevity
- By: Peter Attia MD, Bill Gifford - contributor
- Narrated by: Peter Attia MD
- Length: 17 hrs and 7 mins
- Unabridged
-
Overall
-
Performance
-
Story
Wouldn’t you like to live longer? And better? In this operating manual for longevity, Dr. Peter Attia draws on the latest science to deliver innovative nutritional interventions, techniques for optimizing exercise and sleep, and tools for addressing emotional and mental health.
-
-
Too Much Filler
- By J. Badaracco on 04-09-23
By: Peter Attia MD, and others
-
The Secret Language of Cells
- What Biological Conversations Tell Us About the Brain-Body Connection, the Future of Medicine, and Life Itself
- By: Jon Lieff MD
- Narrated by: George Newbern
- Length: 9 hrs and 55 mins
- Unabridged
-
Overall
-
Performance
-
Story
While cells are commonly considered the building block of living things, it is actually the communication between cells that brings us to life, controlling our bodies and brains, determining whether we are healthy or sick, and directly influencing how we think, feel, and behave. In The Secret Language of Cells, doctor and neuroscientist Jon Lieff lets us listen in on these conversations, and reveals their significance for everything from mental health to cancer.
-
-
top notch!
- By Amazon Customer on 10-11-20
By: Jon Lieff MD
-
An Elegant Defense
- The Extraordinary New Science of the Immune System: A Tale in Four Lives
- By: Matt Richtel
- Narrated by: Fred Sanders
- Length: 12 hrs and 33 mins
- Unabridged
-
Overall
-
Performance
-
Story
A magnificently reported and soulfully crafted exploration of the human immune system - the key to health and wellness, life and death. An epic, first-of-its-kind audiobook, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize-winning New York Times journalist.
-
-
Weak foundation, good conclusion
- By David on 03-24-19
By: Matt Richtel
-
In Love
- A Memoir of Love and Loss
- By: Amy Bloom
- Narrated by: Amy Bloom
- Length: 4 hrs and 49 mins
- Unabridged
-
Overall
-
Performance
-
Story
Amy Bloom began to notice changes in her husband, Brian: He retired early from a new job he loved; he withdrew from close friendships; he talked mostly about the past. Suddenly, it seemed there was a glass wall between them, and their long walks and talks stopped. Their world was altered forever when an MRI confirmed what they could no longer ignore: Brian had Alzheimer’s disease.
-
-
A helpful,healing memoir
- By Helen on 03-31-22
By: Amy Bloom
-
Ten Drugs
- How Plants, Powders, and Pills Have Shaped the History of Medicine
- By: Thomas Hager
- Narrated by: Angelo Di Loreto
- Length: 8 hrs and 39 mins
- Unabridged
-
Overall
-
Performance
-
Story
Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.
-
-
Engrossing to physicians & lay persons alike
- By C. White on 03-08-19
By: Thomas Hager
-
The Facemaker
- A Visionary Surgeon's Battle to Mend the Disfigured Soldiers of World War I
- By: Lindsey Fitzharris
- Narrated by: Daniel Gillies
- Length: 8 hrs and 15 mins
- Unabridged
-
Overall
-
Performance
-
Story
From the moment the first machine gun rang out over the Western Front, one thing was clear: mankind’s military technology had wildly surpassed its medical capabilities. Bodies were battered, gouged, hacked, and gassed. The First World War claimed millions of lives and left millions more wounded and disfigured. In the midst of this brutality, however, there were also those who strove to alleviate suffering. The Facemaker tells the extraordinary story of such an individual: the pioneering plastic surgeon Harold Gillies.
-
-
My favorite author
- By Dani on 06-07-22
-
Breath from Salt
- A Deadly Genetic Disease, a New Era in Science, and the Patients and Families Who Changed Medicine Forever
- By: Bijal P. Trivedi
- Narrated by: Deepti Gupta
- Length: 20 hrs and 35 mins
- Unabridged
-
Overall
-
Performance
-
Story
Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....
-
-
Such a fantastic book!
- By Pamela J. Blaesing on 02-19-21
By: Bijal P. Trivedi
-
The Laws of Medicine
- By: Siddhartha Mukherjee
- Narrated by: Santino Fontana
- Length: 1 hr and 44 mins
- Unabridged
-
Overall
-
Performance
-
Story
Brimming with fascinating historical details and modern medical wonders, this important audiobook is a fascinating glimpse into the struggles and "eureka!" moments that people outside of the medical profession rarely see. Written with Dr. Mukherjee's signature eloquence and passionate prose, The Laws of Medicine is a critical book not just for those in the medical profession but for everyone who is moved to better understand how their health and well-being are being treated.
-
-
Insightful, sincere and succinct. Not Mukherjee's best.
- By Saurav on 12-20-15
-
Radical
- The Science, Culture, and History of Breast Cancer in America
- By: Kate Pickert
- Narrated by: Kate Pickert
- Length: 9 hrs and 3 mins
- Unabridged
-
Overall
-
Performance
-
Story
As a health-care journalist, Kate Pickert knew the emotional highs and lows of medical treatment well - but always from a distance, through the stories of her subjects. That is, until she was unexpectedly diagnosed with an aggressive type of breast cancer at the age of 35. As she underwent more than a year of treatment, Pickert realized that the popular understanding of breast care in America bears little resemblance to the experiences of today's patients and the rapidly changing science designed to save their lives.
-
-
Helpful and Honest
- By Syl on 12-19-19
By: Kate Pickert
-
The Youngest Science
- Notes of a Medicine Watcher
- By: Lewis Thomas
- Narrated by: George Guidall
- Length: 8 hrs and 25 mins
- Unabridged
-
Overall
-
Performance
-
Story
In this partially autobiographical work, best-selling author Lewis Thomas offers insights on subjects as wide-ranging as gender differences, how it feels to be a patient, human vs. computer intelligence, the future of cancer research, and the longevity of the planet—interspersing all with charming anecdotes about his family, his colleagues and himself.
-
-
Pure enchantment. Excellence.
- By Tamara on 06-26-16
By: Lewis Thomas
What listeners say about Living Medicine
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
-
Overall
-
Performance
-
Story
- D. Rembold
- 10-15-23
Fascinating history of what it takes to save lives.
As a Leukemia stem-cell transplant survivor (2017) who was constantly asking questions and wondering who in the world figured out how to save me, I was enthralled by this read.
It was an entirely readable mix of human stories of suffering, hope, and triumph, combined with enough medical facts and jargon to help appreciate the medical advances needed to save my life.
Thank you, Dr. Appelbaum, for this account!
Something went wrong. Please try again in a few minutes.
You voted on this review!
You reported this review!
-
Overall
-
Performance
-
Story
- Cecilia
- 08-13-23
Dr. Appelbaum
This is a wonderful book with a rich History of some of the great minds in medicine! I hope you enjoy it as much as I did.
KennyB
Something went wrong. Please try again in a few minutes.
You voted on this review!
You reported this review!
-
Overall
-
Performance
-
Story
- Bridget Lewis
- 04-16-24
A glimpse into how far medicine has come!
I thoroughly enjoyed this book! As a mom to a bone marrow recipient (leukemia survivor) and a nurse, I loved learning so much more about the history of BMT. The humble beginnings of Dr Thomas and his team and how far they came, how much they over came was inspiring. Going through the process of watching my 5 year old’s bone marrow transplant was incredibly difficult. But after listening to how much went into the science and research to make it possible made me extremely thankful for their hard work. Because of their dedication, my son is 2 years cancer free!
Even though I originally purchased the audio book, the hard copy will be added to my library as well! Listen to this book!
Something went wrong. Please try again in a few minutes.
You voted on this review!
You reported this review!
-
Overall
-
Performance
-
Story
- Mike Pasquarella
- 02-09-24
What stood out most was how much I did not know about the history of bone marrow transplantation.
I loved the historic and personal references in the story of the development of bone marrow transplantation. It really helped me understand more the field that my oldest daughter is in as a certified bone marrow transplant nurse!
Something went wrong. Please try again in a few minutes.
You voted on this review!
You reported this review!