From 1990 to 1995 Dr. Rick Strassman conducted U.S. Government-approved and funded clinical research at the University of New Mexico in which he injected 60 volunteers with DMT, one of the most powerful psychedelics known. His detailed account of those sessions is an extraordinarily riveting inquiry into the nature of the human mind and the therapeutic potential of psychedelics. DMT, a plant-derived chemical found in the psychedelic Amazon brew, ayahuasca, is also manufactured by the human brain. In Strassman's volunteers, it consistently produced near-death and mystical experiences.

A groundbreaking dive into the role psychedelics have played in the origins of Western civilization, and the real-life quest for the Holy Grail that could shake the Church to its foundations.

A young girl called Tozi stands at the bottom of a pyramid, waiting to be led to the top where her heart will be cut out.... Pepillo, a Spanish orphan who serves a sadistic Dominican friar, is aboard the Spanish fleet as it sails towards Mexico.... This is the epic story of the clash of two empires, two armies and two gods of war. Five hundred desperate adventurers are about to pit themselves against the most brutal armies of the ancient Americas, armies hundreds of thousands strong.

Talking about death and dying is considered taboo in polite company, and even in the medical field. Our ideas about dying are confusing at best: Will our memories flash before our eyes? Regrets consume our thoughts? Does a bright light appear at the end of a tunnel? For most people, it will be a slower process, one eased with preparedness, good humor, and a bit of faith. At the forefront of changing attitudes around palliative care is hospice nurse Hadley Vlahos, who shows that end-of-life care can teach us just as much about how to live as it does about how we die.

Terence McKenna hypothesizes that as the North African jungles receded, giving way to savannas and grasslands near the end of the most recent ice age, a branch of our arboreal primate ancestors left the forest canopy and began living in the open areas beyond. There they experimented with new varieties of foods as they adapted, physically and mentally, to the environment. Among the new foods found in this environment were psilocybin-containing mushrooms.

In the summer after graduating from college, Suleika Jaouad was preparing, as they say in commencement speeches, to enter “the real world”. She had fallen in love and moved to Paris to pursue her dream of becoming a war correspondent. The real world she found, however, would take her into a very different kind of conflict zone. It started with an itch - first on her feet, then up her legs, like a thousand invisible mosquito bites. Then a trip to the doctor and, a few weeks shy of her 23rd birthday, a diagnosis: leukemia, with a 35 percent chance of survival.

Alice Carrière tells the story of her unconventional upbringing in Greenwich Village as the daughter of a remote mother, the renowned artist Jennifer Bartlett, and a charismatic father, European actor Mathieu Carrière. From an early age, Alice is forced to navigate her mother’s recovered memories of ritualized sexual abuse, which she turns into art, and her father’s confusing attentions—her childhood is spent in an adult’s world, with little-to-no boundaries or supervision.

In an audiobook that is The Big Sick meets Dad Is Fat, Jeannie Gaffigan, writer/director/producer/accused supermom and wife of best-selling author/comedian Jim Gaffigan, writes with humor and heart about the pear-sized brain tumor she had removed, the toll it took on her enormous family, and the priceless lessons she learned along the way.

After being diagnosed in her early forties with metastatic melanoma - a "rapidly fatal" form of cancer - journalist and mother of two Mary Elizabeth Williams finds herself in a race against the clock. She takes a once-in-a-lifetime chance and joins a clinical trial for immunotherapy, a revolutionary drug regimen that trains the body to vanquish malignant cells. Astonishingly, her cancer disappears entirely in just a few weeks. But at the same time, her best friend embarks on a cancer journey of her own - with very different results.

Narrated with wry wit, unflinching candor, and resounding insight, Shala takes listeners on a riveting journey into the dark and dimly understood inner workings of OCD and its frequent co-conspirator, body dysmorphic disorder (BDD). Thwarted repeatedly as she struggles to escape the clutches of these formidable foes, she finally stumbles upon an unexpected path to freedom. As she journeys into the heart of fear to reclaim her life, she weaves a self-compassionate road map to recovery: to living in an uncertain world and being happy anyway.

Less than 50,000 years ago mankind had no art, no religion, no sophisticated symbolism, no innovative thinking. Then, in a dramatic and electrifying change, described by scientists as "the greatest riddle in human history," all the skills and qualities that we value most highly in ourselves appeared already fully formed, as though bestowed on us by hidden powers. In Visionary, Graham Hancock sets out to investigate this mysterious "before-and-after moment" and to discover the truth about the influences that gave birth to modern human mind.

When their only child was diagnosed with cystic fibrosis (CF) at the age of two, Maryanne O'Hara and her husband were told that Caitlin could live a long life or be dead in a matter of months. Thirty-one years later, Caitlin lost her battle with this devastating disease following an excruciating two-year wait on the transplant list and a last-minute race to locate a pair of healthy lungs. The sudden spiral of events left Maryanne in an existential crisis, searching to find an answer to the eternal question: Why we are here?

We are in the midst of a powerful psychedelic renaissance. After four decades of hibernation, the promise of the psychoactive 60s - that deeper self-awareness, achieved through reality-bending substances and practices, will lead to greater external harmony - is again gaining a major following. The signs are everywhere, from the influence of today's preeminent psychedelic thinker Daniel Pinchbeck, to the renewed interest in the legacy of Terence McKenna, and to the upsurge of collective cultural phenomena like the spectacle of Burning Man.

Jillian Horton, a general internist, has no idea what to expect during her five-day retreat at Chapin Mill, a Zen centre in upstate New York. She just knows she desperately needs a break. At first she is deeply uncomfortable with the spartan accommodations, silent meals, and scheduled bonding sessions. But as the group struggles through awkward first encounters and guided meditations, something remarkable happens: World-class surgeons, psychiatrists, pediatricians and general practitioners open up and share stories about their secret guilt and grief.

In this anthology, edited by best-selling author Graham Hancock, 22 writers illuminate the topic of psychedelics and consciousness like never before. Travel to South America, the American Southwest, outer space, inner space, and back in time to revisit Pahnke's The Good Friday experiment. Explore the effects of ayahuasca, LSD, and much more.

When their only child was diagnosed with cystic fibrosis (CF) at the age of two, Maryanne O'Hara and her husband were told that Caitlin could live a long life or be dead in a matter of months. Thirty-one years later, Caitlin lost her battle with this devastating disease following an excruciating two-year wait on the transplant list and a last-minute race to locate a pair of healthy lungs. The sudden spiral of events left Maryanne in an existential crisis, searching to find an answer to the eternal question: Why we are here?

Growing up abandoned by her father and raised by a single mother, Celeste was determined to create the perfect family - but even perfect families have secrets. Her days are filled with a rewarding career, a devoted husband, and her four-year-old daughter. Celeste is the only one who knows the precarious house of cards her family is built upon - until the day her daughter falls critically ill. Then her world quickly spirals out of control, her secret threatening to destroy her marriage, family, reputation, and sanity.

Adam Stern was a student at a state medical school before being selected to train as a psychiatry resident at one of the most prestigious programs in the country. His new and initially intimidating classmates were high achievers from the Ivy League and other elite universities. Faculty raved about the group as though the residency program had won the lottery, nicknaming them “The Golden Class”, but would Stern ever prove that he belonged? In his memoir, Stern pulls back the curtain on the intense and emotionally challenging lessons he and his fellow doctors learned.

In an idyllic Los Angeles neighborhood, where generations enjoy deep roots in old homes, the O’Rourke family fits right in. Miriam and Craig are both artists and their four children carry on the legacy. When their teenage son, Nick, is diagnosed with schizophrenia, a tumultuous decade ensues in which the family careens off the conventional course. Like the 10 Biblical plagues, they are hit by one catastrophe after another: violence, evictions, arrests, a suicide attempt, a near-drowning - even cancer and a brain tumor - play against the backdrop of a wild teenage bacchanal.

"Something is murdering my men." Thus reads the message received from a Nazi commander stationed in a small castle high in the remote Transylvanian Alps. Invisible and silent, the enemy selects one victim per night, leaving the bloodless and mutilated corpses behind to terrify its future victims. When an elite SS extermination squad is dispatched to solve the problem, the men find something that's both powerful and terrifying. Panicked, the Nazis bring in a local expert on folklore - who just happens to be Jewish - to shed some light on the mysterious happenings.

Laya Marston’s husband, Cameron, a daredevil enthusiast, was the complete opposite of her, ready and willing to dive off a cliff-face or parachute across a canyon - and Laya loved him for it. But she was different: pragmatic, regimented, devoted to her career and to supporting Cameron from the sidelines of his death-defying feats. Opposites attract, right? But when Cameron dies tragically, Laya becomes lost in denial, living in the delusion that Cameron will come back to her.

Chika Jeune was born three days before the devastating earthquake that decimated Haiti in 2010. She spent her infancy in a landscape of extreme poverty, and when her mother died giving birth to a baby brother, Chika was brought to The Have Faith Haiti Orphanage that Albom operates in Port Au Prince. With no children of their own, the 40-plus children who live, play, and go to school at the orphanage have become family to Mitch and his wife, Janine. But at age five, Chika is suddenly diagnosed with something a doctor there says "no one in Haiti can help you with."

With his signature acerbic wit and hilarious voice, 20-something author, blogger, and entrepreneur Shane Burcaw is back with an essay collection about living a full life in a body that many people perceive as a tragedy. From anecdotes about first introductions where people patted him on the head instead of shaking his hand, to stories of passersby mistaking his able-bodied girlfriend for a nurse, Shane tackles awkward situations and assumptions with humor and grace.

When Amy B. Scher was struck with undiagnosed late-stage, chronic Lyme disease, the best physicians in America labeled her condition incurable and potentially terminal. Deteriorating rapidly, she went on a search to save her own life - from the top experts in Los Angeles and the world-renowned Mayo Clinic in Minneapolis to a state-of-the-art hospital in Chicago. After exhausting all of her options in the US, she discovered a possible cure - but it was highly experimental, available only in India, and had as much of a probability of killing her as it did of curing her.

Nearly 26 years after receiving her first heart transplant, Amy Silverstein's donor heart plummeted into failure. If she wanted to live, she had to take on the grueling quest for a new heart - immediately. A shot at survival meant uprooting her life and moving across the country to California. When her friends heard of her plans, there was only one reaction: "I'm there." Nine remarkable women - Joy, Jill, Leja, Jody, Lauren, Robin, Valerie, Ann, and Jane - put demanding jobs and pressing family obligations on hold to fly across the country and be by Amy's side.