Nothing in the universe is more complex than life. Throughout the skies, in oceans, and across lands, life is endlessly on the move. In its myriad forms—from cells to human beings, social structures, and ecosystems—life is open-ended, evolving, unpredictable, yet adaptive and self-sustaining. Complexity theory addresses the mysteries that animate science, philosophy, and metaphysics: how this teeming array of existence, from the infinitesimal to the infinite, is in fact a seamless living whole and what our place, as conscious beings, is within it.

For as long as we’ve studied human cognition, we’ve believed that our senses give us direct access to the world. What we see is what’s really there—or so the thinking goes. But new discoveries in neuroscience and psychology have turned this assumption on its head. What if rather than perceiving reality passively, your mind actively predicts it?

Robert Sapolsky’s Behave, his now classic account of why humans do good and why they do bad, pointed toward an unsettling conclusion: We may not grasp the precise marriage of nature and nurture that creates the physics and chemistry at the base of human behavior, but that doesn’t mean it doesn’t exist. Now, in Determined, Sapolsky takes his argument all the way, mounting a brilliant (and in his inimitable way, delightful) full-frontal assault on the pleasant fantasy that there is some separate self telling our biology what to do.

We are approaching a critical threshold in the history of our species. Everything is about to change. Soon you will live surrounded by AIs. They will organize your life, operate your business, and run core government services. You will live in a world of DNA printers and quantum computers, engineered pathogens and autonomous weapons, robot assistants and abundant energy.

Argentine poet Jorge Luis Borges was madly in love when his life was shattered by painful heartbreak. But the breakdown that followed illuminated an incontrovertible truth—that love is necessarily imbued with loss, that the one doesn’t exist without the other. German physicist Werner Heisenberg was fighting with the scientific establishment on the meaning of the quantum realm’s absurdity when he had his own epiphany—that there is no such thing as a complete, perfect description of reality.

The world is never finished catching up with Vaclav Smil. In his latest and perhaps most digestible book, Invention and Innovation, the prolific author—a favorite of Bill Gates—pens an insightful and fact-filled jaunt through the history of human invention. Impatient with the hype that so often accompanies innovation, Smil offers in this book a clear-eyed corrective to the overpromises that accompany everything from new cures for diseases to AI.

Benjamín Labatut’s When We Cease to Understand the World electrified a global readership. A Booker Prize and National Book Award finalist, and one of the New York Times’ Ten Best Books of the Year, it explored the life and thought of a clutch of mathematicians and physicists who took science to strange and sometimes dangerous new realms. In The MANIAC, Labatut has created a tour de force on an even grander scale.

Let us journey, with beloved physicist Carlo Rovelli, into the heart of a black hole. We slip beyond its horizon and tumble down this crack in the universe. As we plunge, we see geometry fold. Time and space pull and stretch. And finally, at the black hole’s core, space and time dissolve, and a white hole is born. Rovelli has dedicated his career to uniting the time-warping ideas of general relativity and the perplexing uncertainties of quantum mechanics. In White Holes, he reveals the mind of a scientist at work.

From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.

Scientists are learning more and more about how brain activity controls behavior and how neural circuits weigh alternatives and initiate actions. As we probe ever deeper into the mechanics of decision making, many conclude that agency—or free will—is an illusion. In Free Agents, leading neuroscientist Kevin Mitchell presents a wealth of evidence to the contrary, arguing that we are not mere machines responding to physical forces but agents acting with purpose.

From the New York Times best-selling author of Seven Brief Lessons on Physics, The Order of Time, and Helgoland, a closer look at the mind-bending nature of the Universe. What are the elementary ingredients of the world? Do time and space exist? And what exactly is reality? Theoretical physicist Carlo Rovelli has spent his life exploring these questions. He tells us how our understanding of reality has changed over the centuries and how physicists think about the structure of the Universe today.

As a University of Chicago–trained economist and Harvard medical school professor and doctor, Anupam Jena is uniquely equipped to answer these questions. And as a critical care doctor at Massachusetts General who researches health care policy, Christopher Worsham confronts their impact on the hospital’s sickest patients. In this singular work of science and medicine, Jena and Worsham show us how medicine really works, and its effect on all of us.

Fungi are everywhere. Most are harmless, some are helpful. A few are killers. Collectively, infectious fungi are the most devastating agents of disease on Earth, and a fungus that can persist in the environment without its host is here for the long haul. In gripping, accessible prose, Emily Monosson documents how changing climate, trade, and travel are making us all more vulnerable to invasion.

We often think of mathematics and literature as polar opposites. But what if, instead, they were fundamentally linked? In her clear, insightful, laugh-out-loud funny debut, Once Upon a Prime, Professor Sarah Hart shows us the myriad connections between math and literature, and how understanding those connections can enhance our enjoyment of both. As the first woman to hold England’s oldest mathematical chair, Professor Hart is the ideal tour guide, taking us on an unforgettable journey through the books we thought we knew, revealing new layers of beauty and wonder.

In this grand poetic vision of the universe, Lawrence Krauss tells the dramatic story of the discovery of the hidden world that underlies reality - and our place within it. Reality is not what you think or sense - it’s weird, wild, and counterintuitive, and its inner workings seem at least as implausible as the idea that something can come from nothing. With his trademark wit and accessible style, Krauss leads us to realms so small that they are invisible to microscopes, to the birth and rebirth of light, and into the natural forces that govern our existence.