Keeping skin healthy is a booming industry, and yet it seems like almost no one agrees on what actually works. What one person says is vital another says is toxic. We have not cured acne or eczema, allergies keep getting worse, and autoimmune conditions are becoming increasingly common. In Clean, doctor and journalist James Hamblin explores how we got here, examining the science and culture of how we care for our skin today.

In 2015, Barbara Lipska - a leading expert on the neuroscience of mental illness - was diagnosed with melanoma that had spread to her brain. Within months, her frontal lobe, the seat of cognition, began shutting down. She descended into madness, exhibiting dementia- and schizophrenia-like symptoms that terrified her family and coworkers. But miraculously, the immunotherapy her doctors had prescribed worked quickly. Just eight weeks after her nightmare began, Lipska returned to normal. With one difference: she remembered her brush with madness with exquisite clarity.

Eastern Europe, 1944: Three women believe they are pregnant, but are torn from their husbands before they can be certain. Rachel is sent to Auschwitz, unaware that her husband has been shot. Priska and her husband travel there together, but are immediately separated. Also at Auschwitz, Anka hopes in vain to be reunited with her husband. With the rest of their families gassed, these young wives are determined to hold on to all they have left-their lives, and those of their unborn babies.

From the masters of storytelling-meets-science, Patient Zero tells the long and fascinating history of disease outbreaks—how they start, how they spread, the science that lets us understand them, and how we race to destroy them before they destroy us. Written in the authors’ lively style, chapters include gripping medical stories about a particular disease or virus—smallpox, Bubonic plague, polio, HIV—that combine “Patient Zero” narratives, or the human stories behind outbreaks, with historical examinations of missteps, milestones, scientific theories, and more.

As a child growing up in Detroit, Ben Carson (1951-) has a dream of becoming a physician, a dream that rose out of struggles with poverty, racism, and poor grades. As Ben persevered and strove for academic excellence, his life became one of compassion and service. Today, Benjamin Carson, MD, is known as the American neurosurgeon with gifted hands.

Don and Mimi Galvin seemed to be living the American dream. After World War II, Don's work with the Air Force brought them to Colorado, where their 12 children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years, there was an established script for a family like the Galvins—aspiration, hard work, upward mobility, domestic harmony. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse. By the mid-1970s, six of the 10 Galvin boys, one after another, were diagnosed as schizophrenic.

Growing up in the 1960s in the suburbs of Chicago, Meg Kissinger’s family seemed to live a charmed life. With eight kids and two loving parents, the Kissingers radiated a warm, boisterous energy. Whether they were spending summer days on the shores of Lake Michigan, barreling down the ski slopes, or navigating the trials of their Catholic school, the Kissingers always knew how to live large and play hard. But behind closed doors, a harsher reality was unfolding.

It’s hard to give up on the feeling that the life you really want is just out of reach. A beach body by summer. A trip to Disneyland around the corner. A promotion on the horizon. Everyone wants to believe that they are headed toward good, better, best. But what happens when the life you hoped for is put on hold indefinitely?

As a health-care journalist, Kate Pickert knew the emotional highs and lows of medical treatment well - but always from a distance, through the stories of her subjects. That is, until she was unexpectedly diagnosed with an aggressive type of breast cancer at the age of 35. As she underwent more than a year of treatment, Pickert realized that the popular understanding of breast care in America bears little resemblance to the experiences of today's patients and the rapidly changing science designed to save their lives.

Leaving a life marked by crippling setbacks and his father's doubt, in 1967 a 20-something doctor from India arrived in America with only five dollars and the desire to claim his American dream. Faced with an entirely new culture, racism, and the lasting effects of disabling childhood injuries, through hard work and perseverance he overcame all odds. Now having performed over 15,000 open-heart surgeries, more than nearly every surgeon in history, Dr. Singh reflects on his most memorable patients and his incredible personal life.

Over the next ten years, 40 to 60 million people in this country will be admitted to the ICU. Most of these hospitalizations will be sudden, unexpected, and harrowing experiences that can alter patients and their families physically and emotionally, with effects that endure for years. In this rich blend of science, medical history, profoundly humane patient stories, and personal reflection, Dr. Wes Ely describes his mission to prevent patients from being inadvertently harmed by the technology that is keeping them alive.

Blood carries life, yet the sight of it makes people faint. It is a waste product and a commodity pricier than oil. It can save lives and transmit deadly infections. Each one of us has roughly nine pints of it, yet many don’t even know their own blood type. And for all its ubiquitousness, the few tablespoons of blood discharged by 800 million women are still regarded as taboo: menstruation is perhaps the single most demonized biological event.

In the spirit of Oliver Sacks Awakenings and the TV series House, Dr. Eric Manheimer's Twelve Patients is a memoir from the medical director of Bellevue Hospital that uses the plights of 12 very different patients - from dignitaries at the nearby UN, to supermax prisoners from Riker's Island, to illegal immigrants, and Wall Street tycoons - to illustrate larger societal issues.

At the age of 27, Whitney Dafoe was forced to give up his life as a photographer who traveled the world. Bit by bit a mysterious illness stole away the pieces of his life: First, it took the strength of his legs, then his voice, and his ability to eat. The Puzzle Solver follows several years in which he desperately sought answers. Whitney's father, Ron Davis, PhD, a world-class geneticist at Stanford University whose legendary research helped crack the code of DNA, suddenly changed the course of his career in a race against time to cure his son's debilitating condition.

Growing up in a New Jersey factory town in the 1980s, Daisy Hernández believed that her aunt had become deathly ill from eating an apple. No one in her family, in either the United States or Colombia, spoke of infectious diseases, and even into her 30s, she only knew that her aunt had died of a rare illness called Chagas. But as Hernández dug deeper, she discovered that Chagas - or the kissing bug disease - is more prevalent in the United States than the Zika virus.