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Doctored
Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's
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Narrated by:
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Lyle Blaker
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By:
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Charles Piller
About this listen
“Demonstrates how some of the most accomplished and elite scientific gatekeepers may have lied, cheated, squandered trust and endangered lives.”—The Wall Street Journal
For fans of Empire of Pain and Dopesick, an arresting deep dive into how Alzheimer’s disease treatment has been set back by corrupt researchers, negligent regulators, and the profit motives of Big Pharma.
Nearly seven million Americans live with Alzheimer’s disease, a tragedy that is already projected to grow into a $1 trillion crisis by 2050. While families suffer and promises of pharmaceutical breakthroughs keep coming up short, investigative journalist Charles Piller’s Doctored shows that we’ve quite likely been walking the wrong path to finding a cure all along—led astray by a cabal of self-interested researchers, government accomplices, and corporate greed.
Piller begins with a whistleblower—Vanderbilt professor Matthew Schrag—whose work exposed a massive scandal. Schrag found that a University of Minnesota lab led by a precocious young scientist and a Nobel Prize-rumored director delivered apparently falsified data at the heart of the leading hypothesis about the disease. Piller’s revelations of Schrag’s findings stunned the field and the public.
From there, based on years of investigative reporting, this “seminal account of deceit that will long be remembered” (Katherine Eban, author of Bottle of Lies and Vanity Fair special correspondent) exposes a vast network of deceit and its players, all the way up to the FDA. Piller uncovers evidence that hundreds of important Alzheimer’s research papers are based on false data. In the process, he reveals how even against a flood of money and influence, a determined cadre of scientific renegades have fought back to challenge the field’s institutional powers in service to science and the tens of thousands of patients who have been drawn into trials to test dubious drugs. It is a shocking tale with huge ramifications not only for Alzheimer’s disease, but for scientific research, funding, and oversight at large.
©2025 Charles Piller (P)2025 Simon & Schuster AudioListeners also enjoyed...
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- Book One of a Trilogy Unifying Philosophy, Physics, and Metaphysics
- By: Thomas Campbell
- Narrated by: Thomas Campbell
- Length: 11 hrs and 11 mins
- Unabridged
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My Big TOE: Awakening, written by a nuclear physicist in the language of contemporary culture, unifies science and philosophy, physics and metaphysics, mind and matter, purpose and meaning, the normal and the paranormal. The entirety of human experience (mind, body, and spirit) including both our objective and subjective worlds is brought together under one seamless scientific understanding.
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What a Trip (but to where?)
- By Michael on 11-26-13
By: Thomas Campbell
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Inspired
- How to Create Tech Products Customers Love, Second Edition
- By: Marty Cagan
- Narrated by: Marty Cagan
- Length: 7 hrs and 45 mins
- Unabridged
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How do today's most successful tech companies - Amazon, Google, Facebook, Netflix, Tesla - design, develop, and deploy the products that have earned the love of literally billions of people around the world? Perhaps surprisingly, they do it very differently from the vast majority of tech companies. In Inspired, technology product management thought leader Marty Cagan provides listeners with a master class in how to structure and staff a vibrant and successful product organization and how to discover and deliver technology products that your customers will love.
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Great book, terrible audio wanted to ask a refund
- By Srikanth Ramanujam on 11-15-18
By: Marty Cagan
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Welcome to the Universe
- An Astrophysical Tour
- By: Michael A. Strauss, J. Richard Gott, Neil deGrasse Tyson
- Narrated by: Michael Butler Murray
- Length: 17 hrs and 53 mins
- Unabridged
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Welcome to the Universe is a personal guided tour of the cosmos by three of today's leading astrophysicists. Inspired by the enormously popular introductory astronomy course that Neil deGrasse Tyson, Michael A. Strauss, and J. Richard Gott taught together at Princeton, this book covers it all - from planets, stars, and galaxies to black holes, wormholes, and time travel.
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All About What We Know About the Universe - ALL
- By J.B. on 02-17-17
By: Michael A. Strauss, and others
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Ranger Confidential
- Living, Working, and Dying in the National Parks
- By: Andrea Lankford
- Narrated by: Julia Motyka
- Length: 9 hrs and 28 mins
- Unabridged
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The real stories behind the scenery of America’s national parks. For 12 years, Andrea Lankford lived in the biggest, most impressive national parks in the world, working a job she loved. She chaperoned baby sea turtles on their journey to sea. She pursued bad guys on her galloping patrol horse. She jumped into rescue helicopters bound for the heart of the Grand Canyon. She won arguments with bears. She slept with a few too many rattlesnakes. Hell yeah, it was the best job in the world! Fortunately, Andrea survived it.
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Depressing from Cover to Cover
- By Drew (@drewsant) on 04-13-15
By: Andrea Lankford
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Ten Drugs
- How Plants, Powders, and Pills Have Shaped the History of Medicine
- By: Thomas Hager
- Narrated by: Angelo Di Loreto
- Length: 8 hrs and 39 mins
- Unabridged
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Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.
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Engrossing to physicians & lay persons alike
- By C. White on 03-08-19
By: Thomas Hager
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The Theory of Everything: The Quest to Explain All Reality
- By: Don Lincoln, The Great Courses
- Narrated by: Don Lincoln
- Length: 12 hrs and 21 mins
- Original Recording
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At the end of his career, Albert Einstein was pursuing a dream far more ambitious than the theory of relativity. He was trying to find an equation that explained all physical reality - a theory of everything. Experimental physicist and award-winning educator Dr. Don Lincoln takes you on this exciting journey in The Theory of Everything: The Quest to Explain All Reality. Suitable for the intellectually curious at all levels and assuming no background beyond basic high-school math, these 24 half-hour lectures cover recent developments at the forefront of particle physics and cosmology.
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Audible’s Best Science Offering, A Gem
- By MikeB on 12-08-18
By: Don Lincoln, and others
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Intertwined
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Pretend We're Dead
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- By: Tanya Pearson
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In 2018, during an interview with journalist Tanya Pearson, Shirley Manson lamented: "It’s a blanket fact that after September 11th, nonconformist women were taken off the radio.” This comment echoed a reality Pearson had personally witnessed as a musician and a fan, and launched her into a quest to figure out just what happened to these extraordinary female figures. Pretend We’re Dead seeks to answer two big questions.
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The well investigated content and personal interviews
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By: Tanya Pearson
What listeners say about Doctored
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- Alz Sci
- 02-16-25
A one-sided view of the Alzheimer’s field
As an Alzheimer’s researcher I found this very biased and dismissive of the great strides that have been made in our field. Misconduct must always be called out and addressed fully, and for that Mr Piller is to be credited. But beyond that, the book tells a semi-fictional story of our research field.
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