The bestselling author of Leonardo da Vinci and Steve Jobs returns with a “compelling” (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies.

In the winter of 1918, at the height of World War I, history's most lethal influenza virus erupted in an army camp in Kansas, moved east with American troops, then exploded, killing as many as 100 million people worldwide. It killed more people in 24 weeks than AIDS has killed in 24 years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision between modern science and epidemic disease.

Alexander von Humboldt (1769-1859) was an intrepid explorer and the most famous scientist of his age. His restless life was packed with adventure and discovery, whether climbing the highest volcanoes in the world or racing through anthrax-infested Siberia. He came up with a radical vision of nature, that it was a complex and interconnected global force and did not exist for man's use alone. Ironically, his ideas have become so accepted and widespread that he has been nearly forgotten.

The Nazis discovered it. The Allies won the war with it. It conquered diseases, changed laws, and single-handedly launched the era of antibiotics. This incredible discovery was sulfa, the first antibiotic medication. In The Demon Under the Microscope, Thomas Hager chronicles the dramatic history of the drug that shaped modern medicine.

In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field is horizontal gene transfer (HGT), or the movement of genes across species lines. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection - a type of HGT. In The Tangled Tree David Quammen chronicles these discoveries through the lives of the researchers who made them.

Nikola Tesla pursued his ideas for wireless lighting and worldwide wireless electric power distribution in his high-voltage, high-frequency power experiments. Hear more about Tesla in this audiobook.

Did you know that it’s believed Galileo was scolded by the Roman Inquisition for sassing his mom? That Isaac Newton loved to examine soap bubbles? That Albert Einstein loved to collect joke books, and that geneticist Barbara McClintock wore a Groucho Marx disguise in public? With juicy tidbits about everything from favorite foods to first loves, the subjects of Kathleen Krull and Kathryn Hewitt’s Lives of the Scientists: Experiments, Explosions (and What the Neighbors Thought) are revealed as creative, bold, sometimes eccentric - and anything but dull.

Thomas Edison was born into a hard-working but attentive family. He struggled in school and became deaf at an early age. Born on February 11, 1847, Edison would become, arguably, the best-known American inventor of all time. His invention of the light bulb was one of more than 1,000 patents he held during his lifetime. Others included the phonograph, the electrical grid, and motion pictures. His work changed the way we see and hear the world around us.

Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome - an enormous molecular machine made up of a million atoms - that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases.

A preeminent geneticist hunts the Neanderthal genome to answer the biggest question of them all: what does it mean to be human? What can we learn from the genes of our closest evolutionary relatives? Neanderthal Man tells the story of geneticist Svante Pbo’s mission to answer that question, beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in his sequencing of the Neanderthal genome in 2009.

The War on Cancer was run by leaders of industries that made cancer-causing products and sometimes also profited from drugs and technologies for finding and treating the disease. Filled with compelling personalities and never-before-revealed information, The Secret History of the War on Cancer shows how we began fighting the wrong war, with the wrong weapons, against the wrong enemies, a legacy that persists to this day.

When a waiting world learned on April 12, 1955, that Jonas Salk had successfully created a vaccine to prevent poliomyelitis, he became a hero overnight. Born in a New York tenement, humble in manner, Salk had all the makings of a 20th-century icon - a knight in a white coat. In the wake of his achievement, he received a staggering number of awards and honors; for years his name ranked with Gandhi and Churchill on lists of the most revered people.

In 1913, an unschooled young Indian clerk wrote a letter to G. H. Hardy, begging that preeminent English mathematician's opinion on several ideas he had about numbers. Hardy, realizing the letter was the work of a genius, arranged for Srinivasa Ramanujan to come to England. Thus began one of the most remarkable collaborations ever chronicled.

She Has Her Mother's Laugh presents a profoundly original perspective on what we pass along from generation to generation. Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. We need a new definition of what heredity is and, through Carl Zimmer's lucid exposition and storytelling, this resounding tour de force delivers it.

Paul Dirac was among the great scientific geniuses of the modern age. One of the discoverers of quantum mechanics, the most revolutionary theory of the past century, his contributions had a unique insight, eloquence, clarity, and mathematical power. His prediction of antimatter was one of the greatest triumphs in the history of physics.

Jack loves his childhood toy Dur Pig. DP has always been there for him, through good and bad. Until one Christmas Eve something terrible happens - DP is lost. But Christmas Eve is a night for miracles and lost causes, a night when all things can come to life...even toys. And Jack’s newest toy - the Christmas Pig (DP’s annoying replacement) - has a daring plan: Together they’ll embark on a magical journey to seek something lost and to save the best friend Jack has ever known....

The kingdom of Cornucopia was once the happiest in the world. It had plenty of gold, a king with the finest moustache you could possibly imagine, and butchers, bakers, and cheesemongers whose exquisite foods made a person dance with delight when they ate them. Everything was perfect - except for the misty Marshlands to the north, which, according to legend, were home to the monstrous Ickabog. Anyone sensible knew that the Ickabog was just a myth to scare children into behaving. But the funny thing about myths is that sometimes they take on a life of their own.

Olaf, Arendelle’s adorable snowman, loves to read. One day, an unexpected message leads Olaf and his friends Anna, Kristoff, and Sven on a quest for a place known as Haus Biblio, described as a “sea of stories”. This Audible Original spans the group’s journey to Haus Biblio as they cross over mountains, search for monsters under bridges, and have conversations with friendly sheep. During his travels, Olaf makes new friends and hears lots of exciting stories along the way.

Mary Lennox starts her life as an unhappy victim of circumstance. After the loss of her parents, she moves to rural Yorkshire to live with a distant uncle where she resents the wildness of the countryside. At first, she struggles to find a place in this new existence. Although unsure about her surroundings and its occupants, through the gentle guidance of the maid she gradually becomes interested in the story of Mrs Craven, who apparently used to spend her time in a garden at the house, the key to which has vanished.

Belle lives in a beautiful castle with a Beast and Enchanted Objects that have come to life. But that isn’t the strangest thing about the castle. Rose petals and leaves have begun to mysteriously appear in random places, leading Belle and her companions Cogsworth the clock and Lumiere the candelabra on a hunt for an intruder.