As a University of Chicago–trained economist and Harvard medical school professor and doctor, Anupam Jena is uniquely equipped to answer these questions. And as a critical care doctor at Massachusetts General who researches health care policy, Christopher Worsham confronts their impact on the hospital’s sickest patients. In this singular work of science and medicine, Jena and Worsham show us how medicine really works, and its effect on all of us.

Welcome to 97-hour weeks. Welcome to life and death decisions. Welcome to a constant tsunami of bodily fluids. Welcome to earning less than the hospital parking meter. Wave goodbye to your friends and relationships. Welcome to the life of a first-year doctor. Scribbled in secret after endless days, sleepless nights, and missed weekends, comedian and former medical resident Adam Kay’s This Is Going to Hurt provides a no-holds-barred account of his time on the front lines of medicine.

This Is Going to Hurt was the publishing phenomenon of the century, read by many millions, loved by at least fifty of them, and adapted into a major TV series. But it was only part of the story. By turns hilarious, heartbreaking and humbling, Undoctored is about what happens when a doctor hangs up his scrubs, but medicine refuses to let go of him. Undoctored is Adam Kay's funniest and most moving book yet—an astonishing portrait of a life in and out of medicine, from one of Britain's finest storytellers.

In this revolutionary book, renowned physician Gabor Maté eloquently dissects how in Western countries that pride themselves on their healthcare systems, chronic illness and general ill health are on the rise. Nearly 70 percent of Americans are on at least one prescription drug; more than half take two. In Canada, every fifth person has high blood pressure. In Europe, hypertension is diagnosed in more than 30 percent of the population. And everywhere, adolescent mental illness is on the rise. So what is really “normal” when it comes to health?

At the age of thirty-six, on the verge of completing a decade’s worth of training as a neurosurgeon, Paul Kalanithi was diagnosed with stage IV lung cancer. One day he was a doctor treating the dying, and the next he was a patient struggling to live. And just like that, the future he and his wife had imagined evaporated.

Back when restaurant menus were still printed on paper, and wearing a mask—or not—was a decision made mostly on Halloween, David Sedaris spent his time doing normal things. As Happy-Go-Lucky opens, he is learning to shoot guns with his sister, visiting muddy flea markets in Serbia, buying gummy worms to feed to ants, and telling his nonagenarian father wheelchair jokes. But then the pandemic hits, and like so many others, he’s stuck in lockdown, unable to tour and read for audiences, the part of his work he loves most.

When Dr. Scott W. Atlas was tapped by Donald Trump to join his COVID Task Force, he was immediately thrust into a maelstrom of scientific disputes, policy debates, raging egos, politically motivated lies, and cynical media manipulation. Numerous myths and distortions surround the Trump Administration’s handling of the crisis, and many pressing questions remain unanswered.

More than 44 percent of Americans admit to losing sleep over stress. And while most of us do everything we can to reduce it, Stanford psychologist and best-selling author Kelly McGonigal, PhD, delivers a startling message: Stress isn't bad. In The Upside of Stress, McGonigal highlights new research indicating that stress can, in fact, make us stronger, smarter, and happier - if we learn how to embrace it.

This book will help you flourish. With this unprecedented promise, internationally esteemed psychologist Martin Seligman begins Flourish, his first book in 10 years - and the first to present his dynamic new concept of what well-being really is. Traditionally, the goal of psychology has been to relieve human suffering, but the goal of the Positive Psychology movement, which Dr. Seligman has led for 15 years, is different - it’s about actually raising the bar for the human condition.

Despite modern medicine's infatuation with high-tech gadgetry, the single most powerful diagnostic tool is the doctor-patient conversation, which can uncover the lion's share of illnesses. However, what patients say and what doctors hear are often two vastly different things. Patients, anxious to convey their symptoms, feel an urgency to "make their case" to their doctors. Doctors, under pressure to be efficient, multitask while patients speak and often miss the key elements.

The Gender Identity Development Service (GIDS), based at the Tavistock and Portman Trust in North London, was set up initially to provide - for the most part - talking therapies to young people who were questioning their gender identity. But in the last decade GIDS has referred more than a thousand children, some as young as nine years old, for medication to block their puberty. In the same period, the number of referrals has exploded, increasing thirty-fold, while the profile of the patients has changed, from largely pre-pubescent boys to mostly adolescent girls.

In The Price of Silence she takes a devastating look at how we address mental illness, especially in children, who are funneled through a system of education, mental health care, and juvenile detention that leads far too often to prison. In the end she asks one central question: if there's a poster child for cancer, why can't there be one for mental illness? The answer: the stigma.

When Damon Tweedy begins medical school, he envisions a bright future where his segregated, working-class background will become largely irrelevant. Instead, he finds that he has joined a new world where race is front and center. The recipient of a scholarship designed to increase black student enrollment, Tweedy soon meets a professor who bluntly questions whether he belongs in medical school, a moment that crystallizes the challenges he will face throughout his career.

On average, a physician will interrupt a patient describing her symptoms within 12 seconds. In that short time, many doctors decide on the likely diagnosis and best treatment. Often, decisions made this way are correct, but at crucial moments they can also be wrong: with catastrophic consequences. In this myth-shattering book, Jerome Groopman pinpoints the forces and thought processes behind the decisions doctors make.

Jessica Zitter became a doctor because she wanted to be a hero. She elected to specialize in critical care - to become an ICU physician - and imagined herself swooping in to rescue patients from the brink of death. But then during her first code she found herself cracking the ribs of a patient so old and frail it was unimaginable he would ever come back to life. She began to question her choice. Extreme Measures charts Zitter's journey from wanting to be one kind of hero to becoming another - a doctor who prioritizes the patient's values and preferences.

When Damon Tweedy begins medical school, he envisions a bright future where his segregated, working-class background will become largely irrelevant. Instead, he finds that he has joined a new world where race is front and center. The recipient of a scholarship designed to increase black student enrollment, Tweedy soon meets a professor who bluntly questions whether he belongs in medical school, a moment that crystallizes the challenges he will face throughout his career.

If we could turn back the clock psychologically, could we also turn it back physically? For more than 30 years, award-winning social psychologist Ellen Langer has studied this provocative question, and now has a conclusive answer: opening our minds to what's possible, instead of clinging to accepted notions about what's not, can lead to better health at any age.

Dr. Marty Makary is co-developer of the life-saving checklist outlined in Atul Gawande's best-selling The Checklist Manifesto. As a busy surgeon who has worked in many of the best hospitals in the nation, he can testify to the amazing power of modern medicine to cure. But he's also been a witness to a medical culture that routinely leaves surgical sponges inside patients, amputates the wrong limbs, and overdoses children because of sloppy handwriting. Over the last 10 years, neither error rates nor costs have come down, despite scientific progress.

In telling the intimate story of caring for her aged and ailing mother, Jane Gross offers indispensable, and often surprising, advice for the rapidly increasing number of adult children responsible for aging parents. Gross deftly weaves the specifics of her personal experience with a comprehensive resource for effectively managing the lives of one's own parents while keeping sanity and strength intact.

Moneyball meets medicine in this remarkable chronicle of one of the greatest scientific quests of our time - the groundbreaking program to answer the most essential question for humanity: How do we live and die? - and the visionary mastermind behind it.

For more than two years, author and psychotherapist Gary Greenberg has embedded himself in the war that broke out over the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (the DSM) - the American Psychiatric Association's (APA) compendium of mental illnesses and what Greenberg calls "the book of woe". Since its debut in 1952, the book has been frequently revised, and with each revision, the "official" view on which psychological problems constitute mental illness has changed.

Do you live with a chronic, debilitating, yet invisible condition? You may feel isolated, out of step, judged, lonely, or misunderstood - and that's on top of dealing with your actual illness. Take heart. You are not alone, although sometimes it can feel that way. Written by a blogger who suffers from an invisible chronic illness, Surviving and Thriving with an Invisible Chronic Illness offers peer-to-peer support to help you stay sane, be your own advocate, and get back to living your life. This compelling guide is written for anyone suffering with an illness no one can see.

Imagine finding a glimmer of good news in a diagnosis of Alzheimer's. And imagine how that would change the outlook of the five million Americans who suffer from Alzheimer's disease and other dementias, not to mention their families, loved ones, and caretakers. A neurologist who's been specializing in dementia and memory loss for more than 20 years, Dr. Gayatri Devi rewrites the story of Alzheimer's by defining it as a spectrum disorder - like autism, Alzheimer's is a disease that affects different people differently.

America has been the world leader in generating new mental health treatments and modern theories of the human psyche. We export our psychopharmaceuticals packaged with the certainty that our biomedical knowledge will relieve the suffering and stigma of mental illness. We categorize disorders, thereby defining mental illness and health, and then parade these seemingly scientific certainties in front of the world.

In 1930s and 1940s Vienna, child psychiatrist Hans Asperger sought to define autism as a diagnostic category, aiming to treat those children, usually boys, he deemed capable of participating fully in society. Depicted as a compassionate and devoted researcher, Asperger was in fact deeply influenced by Nazi psychiatry. Although he did offer individualized care to children he deemed promising, he also prescribed harsh institutionalization and even transfer to Spiegelgrund for children with greater disabilities, who, he held, could not integrate into the community.

Americans have traditionally placed great value on self-reliance and fortitude. Recent decades, however, have seen the rise of a therapeutic ethic that views Americans as emotionally underdeveloped, requiring the ministrations of mental-health professionals to cope with life's vicissitudes. Today, having a book for every ailment, a counselor for every crisis, a lawsuit for every grievance, and a TV show for every problem degrades one's native ability to cope with life's challenges.

In 2020, an estimated 5.8 million Americans had Alzheimer’s, and more than half a million died because of the disease and its devastating complications. Sixteen million caregivers are responsible for paying as much as half of the $226 billion annual costs of their care. As more people live beyond their 70s and 80s, the number of patients will rise to an estimated 13.8 million by 2025. Part case studies, part meditation on the past, present and future of the disease, The Problem of Alzheimer's traces Alzheimer’s from its beginnings to its recognition as a crisis.

A classic of patient empowerment, Peace, Love & Healing offered the revolutionary message that we have an innate ability to heal ourselves. Now proven by numerous scientific studies, the connection between our minds and our bodies has been increasingly accepted as fact throughout the mainstream medical community. In a new introduction, Dr. Bernie Siegel highlights current research on the relationships among consciousness, psychosocial factors, attitude, and immune function.

In The Sober Truth, acclaimed addiction specialist Dr. Lance Dodes exposes the deeply flawed science that the 12-step industry has used to support its programs. Dr. Dodes analyzes dozens of studies to reveal a startling pattern of errors, misjudgments, and biases. He also pores over the research to highlight the best peer-reviewed studies available and discovers that they reach a grim consensus on the program's overall success.

There’s a quiet revolution happening in the way we die. More than 1.5 million Americans a year die in hospice care - nearly 44 percent of all deaths - and a vast industry has sprung up to meet the growing demand. Once viewed as a New Age indulgence, hospice is now a $14 billion business and one of the most successful segments in health care. Changing the Way We Die, by award-winning journalists Fran Smith and Sheila Himmel, is the first book to take a broad, penetrating look at the hospice landscape.