From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.

In this brilliant book, Isabel Wilkerson gives us a masterful portrait of an unseen phenomenon in America as she explores, through an immersive, deeply researched narrative and stories about real people, how America today and throughout its history has been shaped by a hidden caste system, a rigid hierarchy of human rankings. Beautifully written, original, and revealing, Caste: The Origins of Our Discontents is an eye-opening story of people and history, and a reexamination of what lies under the surface of ordinary lives and of American life today.

Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells - taken without her knowledge - became one of the most important tools in medicine: The first “immortal” human cells grown in culture, which are still alive today, though she has been dead for more than 60 years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects.

The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.

Acclaimed scientist Hope Jahren has built three laboratories in which she's studied trees, flowers, seeds, and soil. Her first book might have been a revelatory treatise on plant life. Lab Girl is that, but it is also so much more. Because in it, Jahren also shares with us her inspiring life story, in prose that takes your breath away.

What’s to be done about a jaywalking moose? A bear caught breaking and entering? A murderous tree? Three hundred years ago, animals that broke the law would be assigned legal representation and put on trial. These days, as New York Times best-selling author Mary Roach discovers, the answers are best found not in jurisprudence but in science: the curious science of human-wildlife conflict, a discipline at the crossroads of human behavior and wildlife biology.

Whether looking at intelligence or emotion, cognition or behavior, science has continued to tell us that men and women are fundamentally different. Biologists claim that women are better suited to raising families or are, more gently, uniquely empathetic. Men, on the other hand, continue to be described as excelling at tasks that require logic, spatial reasoning, and motor skills. But a huge wave of research is now revealing an alternative version of what we thought we knew.

In 1963, a female student was attending a lecture given by Nobel Prize winner James Watson, then tenured at Harvard. At nineteen, she was struggling to define her future. She had given herself just ten years to fulfill her professional ambitions before starting the family she was expected to have. For women at that time, a future on the usual path of academic science was unimaginable—but during that lecture, young Nancy Hopkins fell in love with the promise of genetics. Confidently believing science to be a pure meritocracy, she embarked on a career.

Plenty of experts argue that anyone who wants to develop a skill, play an instrument, or lead their field should start early, focus intensely, and rack up as many hours of deliberate practice as possible. But a closer look at research on the world’s top performers shows that early specialization is the exception, not the rule. David Epstein examined the world’s most successful athletes, artists, musicians, inventors, forecasters and scientists. He discovered that in most fields—especially those that are complex and unpredictable—generalists, not specialists, are primed to excel.

For those who could read between the lines, the censored news out of China was terrifying. But the president insisted there was nothing to worry about. Fortunately, we are still a nation of skeptics. Fortunately, there are those among us who study pandemics and are willing to look unflinchingly at worst-case scenarios. Michael Lewis’ taut and brilliant nonfiction thriller pits a band of medical visionaries against the wall of ignorance that was the official response of the Trump administration to the outbreak of COVID-19.

A celebrated foreign policy expert and key impeachment witness reveals how declining opportunity has set America on the grim path of modern Russia—and draws on her personal journey out of poverty, as well as her unique perspectives as an historian and policy maker, to show how we can return hope to our forgotten places.

New York Times best-selling author Dan Heath examines how to prevent problems before they happen, drawing on insights from his innovative behavior research, as well as hundreds of new interviews with unconventional problem solvers. Most of us spend our days handling a deluge of pressing issues. We’re so accustomed to managing emergencies as they strike that we often don’t stop to think about how we could prevent crises before they happen. Why stop at treating the symptoms when you could develop a cure?

Dr. Judy Mikovits is a modern-day Rosalind Franklin, a brilliant researcher shaking up the old boys' club of science with her groundbreaking discoveries. And like many women who have trespassed into the world of men, she uncovered decades-old secrets that many would prefer to stay buried.

In January 2020, Donald Trump was on the fast track to an easy re-election. While his first two years had been stymied by House Speaker Paul Ryan, Senate Majority Leader Mitch McConnell, and the Democrats, his third year had been one of remarkable success. The United States had low unemployment and was making strides across the globe. The president's rallies were well-attended, and he was being projected to win four hundred electoral votes and about forty-five states. Then came COVID-19.

In September 2016, a woman in Nevada became the first known case in the US of a person who died of an infection resistant to every antibiotic available. Her death is the worst nightmare of infectious disease doctors and public health professionals. While bacteria live within us and are essential for our health, some strains can kill us. As bacteria continue to mutate, becoming increasingly resistant to known antibiotics, we are likely to face a public health crisis of unimaginable proportions.

In 1963, a female student was attending a lecture given by Nobel Prize winner James Watson, then tenured at Harvard. At nineteen, she was struggling to define her future. She had given herself just ten years to fulfill her professional ambitions before starting the family she was expected to have. For women at that time, a future on the usual path of academic science was unimaginable—but during that lecture, young Nancy Hopkins fell in love with the promise of genetics. Confidently believing science to be a pure meritocracy, she embarked on a career.

Lee Hood did that rarest of things. He enabled scientists to see things they couldn't see before and do things they hadn't dreamed of doing. Scientists can now sequence complete human genomes in a day, setting in motion a revolution that is personalizing medicine. Hood, a son of the American West, was an unlikely candidate to transform biology. But with ferocious drive, he led a team at Caltech that developed the automated DNA sequencer, the tool that paved the way for the Human Genome Project.

In 2013, the New York Times published an obituary for Yvonne Brill. It began: “She made a mean beef stroganoff, followed her husband from job to job, and took eight years off from work to raise three children.” It wasn’t until the second paragraph that readers discovered why the Times had devoted several hundred words to her life: Brill was a brilliant rocket scientist who invented a propulsion system to keep communications satellites in orbit, and had recently been awarded the National Medal of Technology and Innovation.

Engrossing and captivating, Editing Humanity takes listeners inside the fascinating world of a new gene editing technology called CRISPR, a high-powered genetic toolkit that enables scientists to not only engineer but to edit the DNA of any organism down to the individual building blocks of the genetic code. Davies introduces listeners to arguably the most profound scientific breakthrough of our time. He tracks the scientists on the front lines of its research to the patients whose powerful stories bring the narrative movingly to human scale.

Few were ready when a mysterious respiratory illness emerged in Wuhan, China, in January 2020. Politicians, government officials, business leaders, and public-health professionals were unprepared for the most devastating pandemic in a century. Many of the world’s biggest drug and vaccine makers were slow to react or couldn’t muster an effective response. It was up to a small group of unlikely and untested scientists and executives to save civilization.

Our current system of higher education dates to the period from 1865 to 1925, when the nation's new universities created grades and departments, majors and minors, in an attempt to prepare young people for a world transformed by the telegraph and the Model T. As Cathy Davidson argues in The New Education, this approach to education is wholly unsuited to the era of the gig economy.

Exploding college prices and a flagging global economy, combined with the derring-do of a few intrepid innovators, have created a dynamic climate for a total rethinking of an industry that has remained virtually unchanged for a hundred years. In The End of College, Kevin Carey, an education researcher and writer, draws on years of in-depth reporting and cutting-edge research to paint a vivid and surprising portrait of the future of education.

The term "home economics" may conjure traumatic memories of lopsided hand-sewn pillows or sunken muffins. But common conception obscures the story of the revolutionary science of better living. The field exploded opportunities for women in the 20th century by reducing domestic work and providing jobs as professors, engineers, chemists, and businesspeople. And it has something to teach us today. Danielle Dreilinger traces the field's history from Black colleges to Eleanor Roosevelt to Okinawa, from a Betty Crocker brigade to DIY techies.

“Doomed from birth” was how psychologist Harold Skeels described two girls at the Orphans’ Home in Davenport, Iowa, in 1934. Following prevailing eugenic beliefs, Skeels and his colleague Marie Skodak assumed that the girls had inherited their parents’ low intelligence and sent them to an institution. To their astonishment, under the women’s care, the children’s IQ scores became normal. Recasting Skeels and his team as intrepid heroes, Marilyn Brookwood weaves years of prodigious archival research to show how after decades of backlash, the Iowans finally prevailed.

Education expert Tony Wagner situates our school problems in the context of the global knowledge economy and analyzes the skills necessary for our young people to succeed.

Bobby and Cheryl Love were living in Brooklyn, happily married for decades, when the FBI and NYPD appeared at their door and demanded to know from Bobby, in front of his shocked wife and children: “What is your name? No, what’s your real name?” Bobby’s thirty-eight-year secret was out. As a Black child in the Jim Crow South, Bobby found himself in legal trouble before his 14th birthday. Sparked by the desperation he felt in the face of limited options and the pull of the streets, Bobby became a master thief.

In January 2020, Donald Trump was on the fast track to an easy re-election. While his first two years had been stymied by House Speaker Paul Ryan, Senate Majority Leader Mitch McConnell, and the Democrats, his third year had been one of remarkable success. The United States had low unemployment and was making strides across the globe. The president's rallies were well-attended, and he was being projected to win four hundred electoral votes and about forty-five states. Then came COVID-19.

This comprehensive and gripping narrative, which received the 2006 Pulitzer Prize for history, covers all the challenges, characters, and controversies in America's relentless struggle against polio. Funded by philanthropy and grassroots contributions, Salk's killed-virus vaccine (1954) and Sabin's live-virus vaccine (1961) began to eradicate this dreaded disease.

Grounded in extensive research and reporting, Spy Schools reveals how academia has emerged as a frontline in the global spy game. In a knowledge-based economy, universities are repositories of valuable information and research, where brilliant minds of all nationalities mingle freely with few questions asked. Intelligence agencies have always recruited bright undergraduates, but now, in an era when espionage increasingly requires specialized scientific or technological expertise, they're wooing higher-level academics.

From the cranberry bogs of Massachusetts to the classrooms of Singapore and Finland, from tiny start-ups to global engineering firms and beloved American organizations like Ocean Spray, Eileen Fisher, Gore, and Boston Scientific, Heffernan discovers ways of living and working that foster creativity, spark innovation, reinforce our social fabric, and feel so much better than winning.