Medical History

In 1953, a 27-year-old factory worker named Henry Molaison - who suffered from severe epilepsy - received a radical new version of the then-common lobotomy, targeting the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry was left profoundly amnesic, unable to create long-term memories. Over the next 60 years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.

Ingrassia lost his mother, two sisters, brother, and nephew to cancer—different cancers developing at different points throughout their lives. And while highly unusual, his family is not the only one to wonder whether their heartbreak is the result of unbelievable bad luck, or if there might be another explanation. Through meticulous research and riveting storytelling, Ingrassia takes us from the 1960s—when Dr. Frederick Pei Li and Dr. Joseph Fraumeni Jr. first met, not yet knowing that they would help make a groundbreaking discovery that would affect cancer patients for decades to come.

Dr. John Sullivan is the medical director of the Philadelphia General Hospital’s Alzheimer’s unit. He’s also a member of the West Philadelphia Historical Society, spearheading an effort to document as much information as possible regarding the hospital’s Franklin Wing, an abandoned section of the medical complex set to be razed. During his research, Dr. Sullivan acquaints himself with Dr. Zachary Schmidt, an eccentric and at times controversial physician who worked in the Franklin Wing until his mysterious disappearance on July 4th, 1976. There, in Dr. Schmidt’s former office, ...

Every medical decision - whether to have chemotherapy, an X-ray, or surgery - is a risk, no matter which way you choose. In You Bet Your Life, physician Paul A. Offit argues that, from the first blood transfusions 400 years ago to the hunt for a COVID-19 vaccine, risk has been essential to the discovery of new treatments. More importantly, understanding the risks is crucial to whether, as a society or as individuals, we accept them.

Due to horrible physical deformities, he spent much of his life as a fairground freak. He was hounded, persecuted, and starving, until his fortune changed and he was rescued, housed, and fed by the distinguished surgeon, Frederick Treves. The subject of several books, a Broadway hit, and a film, Joseph Merrick has become part of popular mythology. Here, in this fully revised edition containing much fresh information, are the true and un-romanticized facts of his life.

Long before the U.S. government began conducting secret radiation and germ-warfare experiments, and long before the Tuskegee syphilis experiments, medical professionals had introduced—and hotly debated the ethics of—the use of human subjects in medical experiments. In Subjected to Science, Susan Lederer provides the first full-length history of biomedical research with human subjects in the earlier period, from 1890 to 1940.

From Canada’s top war historian, a definitive medical history of the Great War, illuminating how the carnage of modern battle gave birth to revolutionary life-saving innovations. It brings to light shocking revelations of the ways the brutality of combat and the necessity of agonizing battlefield decisions led to unimaginable strain for men and women of medicine who fought to save the lives of soldiers.

Patti Davis, the daughter of Ronald and Nancy Reagan, writes about losing her father to Alzheimer's disease, saying goodbye in stages, and watching the progression of a disease that steals what is most precious: a person's memory. Past and present come together in this illuminating portrait of grief, of a man, a disease, and a girl and her father.

The Elephant Man is Treves' own firsthand account of how he met and befriended Joseph Merrick (whom he mistakenly calls John Merrick), a young man with very severe physical deformities, who was being exhibited as a sideshow freak, as half man, half elephant. Treves initially invited Merrick to his rooms in the London Hospital so as to examine him, and to ensure Merrick's admittance he gave him his card.

The Cancer Problem offers the first medical, cultural, and social history of cancer in 19th-century Britain. It argues that it was in the 19th century that cancer acquired the unique emotional, symbolic, and politicized status it maintains today. Through an interrogation of the construction, deployment, and emotional consequences of the disease's incurability, this book reframes our conceptualization of the relationship between medicine and modern life and reshapes our understanding of chronic and incurable maladies, both past and present.

Intensive care units and mechanical ventilation are the crucial foundation of modern medical care: without them, the appalling death toll of the COVID-19 pandemic would be even higher. In The Autumn Ghost, Dr. Hannah Wunsch traces the origins of these two innovations back to a polio epidemic in the autumn of 1952. Drawing together testimony from doctors, nurses, medical students, and patients, Wunsch relates a gripping tale of an epidemic that changed the world.

At the 1993 Battle of Mogadishu, dramatized by the popular film Black Hawk Down, the majority of soldiers who died were killed instantly or bled to death before they could reach an operating table. This tragedy reinforced the need for a revolutionary treatment that could transform trauma medicine. So, when Frank Hursey and Bart Gullong—who had no medical or military experience—discovered that a cheap, crushed rock called zeolite had blood‑clotting properties, they brought it to the military's attention. The Marines and the Navy adopted the resulting product, QuikClot, immediately.

Author Leslie Lehr wants to talk about boobs. She’s gone from size AA to DDD and everything between, from puberty to motherhood, enhancement to cancer, and beyond. And she’s not alone - these are classic life stages for women today. At turns funny and heartbreaking, A Boob’s Life explores both the joys and hazards inherent to living in a woman’s body. Lehr deftly blends her personal narrative with national history, starting in the 1960s with the women’s liberation movement and moving to the current feminist dialogue and what it means to be a woman.

When Dr. David Hosack tilled the country's first botanical garden in the Manhattan soil more than 200 years ago, he didn't just dramatically alter the New York landscape; he left a monumental legacy of advocacy for public health and wide-ranging support for the sciences. In melodic prose, historian Victoria Johnson eloquently chronicles Hosack's tireless career to reveal the breadth of his impact. The result is a lush portrait of the man who gave voice to a new, deeply American understanding of the powers and perils of nature.

In 1918, a world war raged, and a lethal strain of influenza circled the globe. In the midst of all this death, a bizarre disease appeared in Europe. Eventually known as encephalitis lethargica, or sleeping sickness, it spread worldwide, leaving millions dead or locked in institutions. Then, in 1927, it disappeared as suddenly as it had arrived. Asleep, set in 1920s and '30s New York, follows a group of neurologists through hospitals and asylums as they try to solve this epidemic and treat its victims - who learned the worst fate was not dying of it, but surviving it.

From the 15th to the mid-19th centuries, scurvy caused more deaths at sea than storms, shipwrecks, combat, and all other diseases combined. The cure for scurvy ranks among the greatest of military successes, yet its impact on history has mostly been ignored. In this book, Stephen R. Brown delivers a lively recounting of how three determined individuals overcame the constraints of 18th century thinking to solve the greatest medical mystery of their era. Brimming with tales of ships, sailors, and bureaucracy, Brown presents a vivid picture of life aboard the ship during the age of sail.

Jeanne Marie Laskas first met the young forensic pathologist Dr. Bennet Omalu in 2009, while reporting a story for GQ that would go on to inspire the movie Concussion. Omalu told her about a day in September 2002, when, in a dingy morgue in downtown Pittsburgh, he picked up a scalpel and made a discovery that would rattle America in ways he’d never intended. Omalu was new to America, chasing the dream, a deeply spiritual man escaping the wounds of civil war in Nigeria.

Dr. Sartor wrote an inspiring first-person account of how he treated more than 1,000 patients—and by his reckoning, lost only five—which lay forgotten in a lockbox of family artifacts until it was discovered decades later by his granddaughter, Beth Obermeyer, a journalist and author of three previous books. Beth knew her grandfather through her teenage years and grew up absorbing family stories. Based upon Dr. Sartor’s memoir and her years of research, she vividly reconstructs his life from childhood in Luxembourg to medical school in Chicago, courtship and marriage.

The heart of many hospitals is the Neonatal Intensive Care Unit (NICU). It is a place where humanity, ethics, and science collide in dramatic and deeply personal ways as parents, doctors, and nurses grapple with sometimes unanswerable questions: When does life begin? When and how should life end? And what does it mean to be human? Nearly 20 years ago, Dr. John D. Lantos wrote The Lazarus Case, a seminal work on ethical dilemmas in neonatology. He described the NICU as “a strong, strange, powerful place”. The

Widely known today as the "Angel of the Battlefield", Clara Barton's personal life has always been shrouded in mystery. In Clara Barton, Professional Angel, Elizabeth Brown Pryor presents a biography of Barton that strips away the heroic exterior and reveals a complex and often trying woman. Based on the papers Clara Barton carefully saved over her lifetime, this biography is the first one to draw on these recorded thoughts. Not always altruistic, her accomplishments were nonetheless extraordinary.