Industrial History

Bradwel reminds us that the centenary of this apparent "wonder drug" should be no cause for celebration. Insulin often remains inaccessible to those who need it most: elusive prescriptions, uneven availability and sky-high prices result in rationing and desperate do-it-yourself research and development. In the face of bootstraps rhetoric and "Pharma Bro" capitalists, patients across the world are left to fend for themselves. There is a long way to go in the twenty-first century until insulin truly fulfills the extraordinary promises made by its discovery.

As scientists confidently look forward to average life expectancies hitting 100+ years in some Western societies, it’s easy to forget how precarious our grasp on good health has been. It is a struggle no better demonstrated than by the myriad and extraordinary measures that humans have gone to – as diverse as animal sacrifice to stem cell transplants – in their quest to stave off death and disease. Acclaimed historian Mark Jackson takes a fresh global view of mankind’s great battle, exploring both Western and Eastern traditions.

A world-renowned psychiatrist reveals the fascinating story of psychiatry's origins, demise, and redemption. Psychiatry has come a long way since the days of chaining "lunatics" in cold cells and parading them as freakish marvels before a gaping public. But as Jeffrey Lieberman reveals in his extraordinary and eye-opening book, the path to legitimacy for "the black sheep of medicine" has been anything but smooth.

In this panoramic account, we learn how great epidemics have not only led to enormous suffering and mass death but also changed the course of history. Humanity has struck back at the microbes: antibiotics and new vaccines have saved millions of lives. But the battle is far from won. We face increasing threats from new and unavoidable pandemics, antibiotic resistance, and even potential extraterrestrial microbes. Duel Without End is a fascinating journey through the long history of infection, from the dawn of life to humanity's future exploration of deep space.

Part memoir, part searing revelation, Seen Yet Unseen takes listeners behind the scenes of some of the world’s biggest tech companies and exposes the way their exclusion of and, at times, hostility toward Black women have lasting impacts on the technology we use every day.

Rabies enjoys a fearsome and lurid reputation. Throughout the decades of spiraling growth that defined New York City from the 1840s to the 1910s, the bone-chilling cry of "Mad dog!" possessed the power to upend the ordinary routines and rhythms of urban life. In Mad Dogs and Other New Yorkers, Jessica Wang examines the history of this rare but dreaded affliction during a time of rapid urbanization.

For the first time, Appetite for Self-Destruction recounts the story of the precipitous rise and fall of the recording industry over the past three decades, when the incredible success of the CD turned the music business into one of the most glamorous, high-profile industries in the world - and the advent of file sharing brought it to its knees.

The gripping story of a chemical weapons catastrophe, the cover-up, and how one American Army doctor’s discovery led to the development of the first drug to combat cancer, known today as chemotherapy.

In Longshot, investigative journalist David Heath takes listeners inside the small group of scientists whose groundbreaking work was once largely dismissed but whose feat will now eclipse the importance of Jonas Salk’s polio vaccine in medical history. With never-before-reported details, Heath reveals how these scientists overcame countless obstacles to give the world an unprecedented head start when we needed a COVID-19 vaccine.

Tales of Hardship, Love and Happiness in Tate & Lyle’s East End Factories. On an autumn day in 1944, Ethel Alleyne walked the short distance from her house to Tate & Lyle’s refinery on the shining curve of the Thames. Looking up at the giant gates, Ethel felt like she had been preparing for this moment all her life. She smoothed down her frizzy hair, scraped a bit of dirt off the corner of her shoe and strode through. She was quite unprepared for the sight that met her eyes …

In this fascinating new exploration of mental illness, Professor Brendan Kelly examines ‘madness’ in history and how we have responded to it over the centuries. We travel from the psychiatric institutions of modern India to scientific studies of the brain in Victorian England. We discover the beginnings of formal asylum care and witness the experimental therapies of the cavernous psychiatric hospitals of the 19th and early 20th centuries in Ireland, England, Belgium, Italy, Germany and the United States.

The number of soldiers wounded in World War I is, in itself, devastating: over 21 million military wounded, and nearly 10 million killed. On the battlefield, the injuries were shocking, unlike anything those in the medical field had ever witnessed. The bullets hit fast and hard, went deep, and took bits of dirty uniform and airborne soil particles in with them. Soldier after soldier came in with the most dreaded kinds of casualty: awful, deep, ragged wounds to their heads, faces, and abdomens.

Stuart Jamieson's story is the story of four decades of advances in heart surgery. Taut, elegantly crafted, and ever-attentive to the patients for whom he was the last best chance, Close to the Sun is an adventurous, riveting account based on the experience of over 40,000 heart surgeries, where everything was on the line every moment in the O.R.

In Lost, medical historian Shannon Withycombe weaves together women’s personal writings and doctors’ publications from the 1820s through the 1910s to investigate the transformative changes in how Americans conceptualized pregnancy, understood miscarriage, and interpreted fetal tissue over the course of the 19th century. Withycombe’s pathbreaking research reveals how Americans construed, and continue to understand, miscarriage within a context of reproductive desires, expectations, and abilities.

The struggle against deadly microbes is endless. Diseases that have plagued human beings since ancient times still exist, new maladies make their way into the headlines, we are faced with vaccine shortages, and the threat of germ warfare has reemerged as a worldwide threat. In this riveting account, medical historian Howard Markel takes an eye-opening look at the fragility of the American public health system.

One of America's greatest investigative reporters brings to life the gripping, no-holds-barred clash of two American titans: Robert Kennedy and his nemesis, Jimmy Hoffa. From 1957 to 1964, Robert Kennedy and Jimmy Hoffa channeled nearly all of their considerable powers into destroying each other. Kennedy's battle with Hoffa burst into the public consciousness with the 1957 Senate Rackets Committee hearings and intensified when his brother named him attorney general in 1961.

A quarter of a million people braved miserable conditions at Epsom Downs on June 2, 1954, to see the 175th running of the prestigious Derby Stakes. Queen Elizabeth II and Sir Winston Churchill were in attendance, along with thousands of Britons who were all convinced of the unfailing superiority of English bloodstock and eager to see a British colt take the victory. They were shocked when a Kentucky-born chestnut named Never Say Die galloped to a two-length triumph at odds of 33-1.

Habitual drug use in the United States is at least as old as the nation itself. Habit Forming traces the history of unregulated drug use and dependency before 1914, when the Harrison Narcotic Tax Act limited sales of opiates and cocaine under US law. Many Americans used opiates and other drugs medically and became addicted. Some tried Hasheesh Candy, injected morphine, or visited opium dens, but neither use nor addiction was linked to crime, due to the dearth of restrictive laws. After the Civil War, American presses published extensively about domestic addiction.

A vibrant young Hispano woman, Shonnie Medina, inherits a breast-cancer mutation known as BRCA1.185delAG. It is a genetic variant characteristic of Jews. The Medinas knew they were descended from Native Americans and Spanish Catholics, but they did not know that they had Jewish ancestry as well. The mutation most likely sprang from Sephardic Jews hounded by the Spanish Inquisition. The discovery of the gene leads to a fascinating investigation of cultural history and modern genetics by Dr. Harry Ostrer and other experts on the DNA of Jewish populations.

Dr. Mackowiak, a professor at the University of Maryland School of Medicine, offers a gripping and authoritative account of 13 patients who took center stage in world history. The result is a new understanding of how the past unfolded, as well as a sweeping survey of the history of medicine. What was the ailment that drove Caligula mad? Why did Stonewall Jackson die after having an arm amputated, when so many other Civil War soldiers survived such operations?