Industrial Engineering

The United States is embarking on a medical revolution. Supporters of personalized, or precision, medicine—the tailoring of health care to our genomes—have promised to usher in a new era of miracle cures. Advocates of this gene-guided health-care practice foresee a future where skyrocketing costs can be curbed by customization and unjust disparities are vanquished by biomedical breakthroughs. Progress, however, has come slowly, and with a price too high for the average citizen.

A vibrant young Hispano woman, Shonnie Medina, inherits a breast-cancer mutation known as BRCA1.185delAG. It is a genetic variant characteristic of Jews. The Medinas knew they were descended from Native Americans and Spanish Catholics, but they did not know that they had Jewish ancestry as well. The mutation most likely sprang from Sephardic Jews hounded by the Spanish Inquisition. The discovery of the gene leads to a fascinating investigation of cultural history and modern genetics by Dr. Harry Ostrer and other experts on the DNA of Jewish populations.

Ignác Semmelweis is remembered for the now-commonplace notion that doctors must wash their hands before examining patients. In mid-19th century Vienna, however, this was a subversive idea. With deaths from childbed fever exploding, Semmelweis discovered that doctors themselves were spreading the disease. While his simple reforms worked immediately - childbed fever in Vienna all but disappeared - they brought down upon Semmelweis the wrath of the establishment, and led to his tragic end.

Fashion is political. From the red carpets of the Met Gala to online fast fashion, clothes tell a story of inequality, racism and climate crisis. In The Anti-Capitalist Book of Fashion, Tansy E. Hoskins unpicks the threads of capitalist industry to reveal the truth about our clothes.

Scientists have long struggled to make pregnancy easier, safer, and more successful. In The Dance of Life, developmental and stem-cell biologist Magdalena Zernicka-Goetz takes us to the front lines of efforts to understand the creation of a human life. She has spent two decades unraveling the mysteries of development, as a simple fertilized egg becomes a complex human being of 40 trillion cells. Zernicka-Goetz's work is both incredibly practical and astonishingly vast.

From Joseph Romm, Chief Science Advisor for National Geographic's Years of Living Dangerously series and one of Rolling Stone's "100 people who are changing America," Climate Change offers user-friendly, scientifically rigorous answers to the most difficult (and commonly politicized) questions surrounding what climatologist Lonnie Thompson has deemed "a clear and present danger to civilization."

Johns Hopkins University, one of the preeminent medical schools in the nation today, has played a unique role in the history of medicine. When it first opened its doors in 1893, medicine was a rough-and-ready trade. It would soon evolve into a rigorous science. In recent years, medical science has mapped the human genome, deployed robotic tools to perform delicate surgeries, and developed effective vaccines against a host of deadly pathogens. But this transformation could not have happened without the game-changing vision, talent, and dedication of a small cadre of individuals.

The beginning of the modern contraceptive era began in 1882, when Dr. Aletta Jacobs opened the first birth control clinic in Amsterdam. The founding of this facility, and the clinical provision of contraception that it enabled, marked the moment when physicians started to take the prevention of pregnancy seriously as a medical concern. In this volume in the MIT Press Essential Knowledge series, Donna Drucker traces the history of modern contraception, outlining the development, manufacturing, and use of contraceptive methods from the opening of Dr. Jacobs' clinic to the present.

Best-selling author Simon Winchester writes a magnificent history of the pioneering engineers who developed precision machinery to allow us to see as far as the moon and as close as the Higgs boson. Precision is the key to everything. It is an integral, unchallenged and essential component of our modern social, mercantile, scientific, mechanical and intellectual landscapes. The items we value in our daily lives - a camera, a phone, a computer, a bicycle, a car, a dishwasher perhaps - all sport components that fit together with precision and operate with near perfection....

This gripping narrative explores today's scientific pursuit of immortality, with exclusive visits inside Silicon Valley labs and interviews with the visionaries who believe we will soon crack into the aging process and cure death. We live in an age when billionaires are betting their fortunes on laboratory advances to prove aging unnecessary and death a disease that can be cured.

The twists and turns of the last 15 years of the Qantas story contain all the ingredients of a corporate thriller, with constant shocks to the system, and boardroom dramas and disasters narrowly avoided. During this tumultuous period, as CEO of Australia's iconic airline, Alan Joyce became one of the best-known corporate figures in Australia, and one of the most polarising. Global aviation expert Peter Harbison tells the full and unvarnished story of this fascinating period of the Qantas journey.

In Unnatural Companions, journalist Peter Christie issues a call to action for pet owners. If we hope to reverse the alarming trend of wildlife decline, pet owners must acknowledge the pets-versus-conservation dilemma and concede that our well-fed and sheltered cats too often prey on small backyard wildlife and seemingly harmless reptiles released into the wild might be the next destructive invasive species. We want our pets to eat nutritionally healthy food, but how does the designer food we feed them impact the environment?

Again and again, microbes have shaped our health, our genetics, our history, our culture, our politics, even our religion and ethics. This book reveals much that scientists and cultural historians have learned about the pervasive interconnections between infectious microbes and humans. It also considers what our ongoing fundamental relationship with infectious microbes might mean for the future of the human species.

Alexandra Morton has been called "the Jane Goodall of Canada" because of her passionate thirty-year fight to save British Columbia's wild salmon. Her account of that fight is both inspiring in its own right and a roadmap of resistance.

Rabies enjoys a fearsome and lurid reputation. Throughout the decades of spiraling growth that defined New York City from the 1840s to the 1910s, the bone-chilling cry of "Mad dog!" possessed the power to upend the ordinary routines and rhythms of urban life. In Mad Dogs and Other New Yorkers, Jessica Wang examines the history of this rare but dreaded affliction during a time of rapid urbanization.

An estimated 10 percent of Americans are implanted with medical devices - like pacemakers, artificial hips, cardiac stents, etc. The overwhelming majority of high-risk implanted devices have never undergone a single clinical trial. The FDA lets device manufacturers decide whether to report serious complications or deaths that may have been caused by their products. Here, award-winning journalist Jeanne Lenzer brings these horrifying statistics to life through the story of one working-class man who, after his "cure" nearly kills him, ends up in a battle for justice.

We can't live without the internet, but we know very little about the secret industry that keeps the wheels of modern life turning; the data centre industry. This is where the internet lives. This is the industry that has the power to make or break our connections. Cloaked in mystery, with secrets, scandals, and bloodthirsty boardroom battles raging behind the scenes, this is where the magic happens. Michael Tobin OBE has been at the forefront of the data centre industry since its birth. This is his never-before-published account of the explosion of the data centre industry.

What did 19th-century cities smell like? And how did odors matter in the formation of a modern environmental consciousness? Smell Detectives follows the 19th-century Americans who used their noses to make sense of the sanitary challenges caused by rapid urban and industrial growth.

When Lucie Amundsen had a rare night out with her husband, she never imagined what he'd tell her over dinner - that his dream was to quit his office job (with benefits!) and start a commercial-scale pasture-raised egg farm. His entire agricultural experience consisted of raising five backyard hens, none of whom had yet laid a single egg. To create this pastured poultry ranch, the couple scrambles to acquire nearly 2,000 chickens - all named Lola.

In a triumph of marketing, the Tasmanian salmon industry has for decades succeeded in presenting itself as world's best practice and its product as healthy and clean, grown in environmentally pristine conditions. But what are we eating when we eat Tasmanian salmon? Richard Flanagan's expose of the salmon farming industry in Tasmania is chilling. In the way that Rachel Carson took on the pesticide industry in her groundbreaking book Silent Spring, Flanagan tears open an industry that is as secretive as its practices are destructive and its product disturbing.