History Medicine Science

The Gene is the story of one of the most powerful and dangerous ideas in our history, from best-selling, prize-winning author Siddhartha Mukherjee. Spanning the globe and several centuries, The Gene is the story of the quest to decipher the master code that makes and defines humans, that governs our form and function. The story of the gene begins in an obscure Augustinian abbey in Moravia in 1856, where a monk stumbles on the idea of a 'unit of heredity'.

The Tragedy of American Science explores how the US economy’s addiction to military spending distorts and deforms science by making it overwhelmingly subservient to military interests. The primary motive driving American science and technology has become the search for new and more efficient ways to kill people. This transforms science from the classic ideal of a creative force for the advancement of humankind into its destructive and antihuman opposite.

In 2020, an estimated 5.8 million Americans had Alzheimer’s, and more than half a million died because of the disease and its devastating complications. Sixteen million caregivers are responsible for paying as much as half of the $226 billion annual costs of their care. As more people live beyond their 70s and 80s, the number of patients will rise to an estimated 13.8 million by 2025. Part case studies, part meditation on the past, present and future of the disease, The Problem of Alzheimer's traces Alzheimer’s from its beginnings to its recognition as a crisis.

Little more than 100 years ago, maps of the world still boasted white space: places where no human had ever trod. Within a few short decades the most hostile of the world's environments had all been conquered. Likewise, in the 20th century, medicine transformed human life. Doctors took what was routinely fatal and made it survivable. As modernity brought us ever more into different kinds of extremes, doctors pushed the bounds of medical advances and human endurance. Extreme exploration challenged the body in ways that only the vanguard of science could answer.

The steady beating back of infant and child mortality is one of our greatest human achievements. Interweaving her own experiences as a medical student and doctor, Perri Klass pays tribute to groundbreaking women doctors like Rebecca Lee Crumpler, Mary Putnam Jacobi, and Josephine Baker, and to the nurses, public health advocates, and scientists who brought new approaches and scientific ideas about sanitation and vaccination to families.

During the worst smallpox epidemic in Boston history, Mather convinced Doctor Boylston to try a procedure that he believed would prevent death - by making an incision in the arm of a healthy person and implanting it with smallpox. "Inoculation" led to vaccination, one of the most profound medical discoveries in history.

This humbling and revelatory book shows how infectious disease has shaped humanity at every stage, from the first success of Homo sapiens over the equally intelligent Neanderthals to the fall of Rome and the rise of Islam. How did an Indonesian volcano help cause the Black Death, setting Europe on the road to capitalism? How could 168 men extract the largest ransom in history from an opposing army of eighty thousand? The latest science reveals that infectious diseases are not just something that happens to us, but a fundamental part of who we are.

In 1995, a scandal erupted when the New York Times revealed that the Smithsonian possessed a century’s worth of nude “posture” photos of college students. In this riveting history, Beth Linker tells why these photos were only a small part of the incredible story of twentieth-century America’s largely forgotten posture panic—a decades-long episode in which it was widely accepted as scientific fact that Americans were suffering from an epidemic of bad posture, with potentially catastrophic health consequences.

Thought of as the seat of our soul, then as a mysteriously animated object, the heart is still more a mystery than it is understood. Why do most animals only get one billion beats? (And how did modern humans get to over two billion - effectively letting us live out two lives?) Why are sufferers of gingivitis more likely to have heart attacks? And what does it really feel like to touch your own heart, or to have someone else's beating inside your chest?

Building a Resilient Tomorrow does not dwell on overhyped descriptions of apocalyptic climate scenarios, nor does it travel down well-trodden paths surrounding the politics of reducing carbon emissions. Instead, it starts with two central facts: Climate impacts will continue to occur, and we can make changes now to mitigate their effects.

In this ground-breaking history Elinor Cleghorn unpacks the roots of the perpetual misunderstanding, mystification and misdiagnosis of women's bodies, illness and pain. From the 'wandering womb' of ancient Greece to today's shifting understanding of hormones, menstruation and menopause, Unwell Women is the revolutionary story of women who have suffered, challenged and rewritten medical misogyny. Drawing on Elinor's own experience as an unwell woman, this is a powerful and timely exposé of the medical world and woman's place within it.

The year is 1925. It is sixty degrees below zero. The wind sweeps tons of snow over the deep-frozen Alaskan landscape. The nearest railhead is seven hundred miles away. Airplanes cannot fly. The way to Nome is blocked by a treacherous frozen sound, an icebound port, and mountains to the west. But there is a diphtheria epidemic in Nome. The children need serum from the outside world if they are to survive. Their only hope is a few chosen Eskimo drivers and their teams of dogs.

As late as the 1930s, virtually no drug intended for sickness did any good; doctors could set bones, deliver babies, and offer palliative care. That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955 the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections.

The Zodiac and the Salts of Salvation is a two-part work first published in 1932 by frequent collaborators Dr. George Washington Carey (1845-1924) and Inez Eudora Perry (1871-1961). This book explores the use of certain minerals called “cell-salts” to cure disease and how one's Zodiac sign impacts their cell-salt deficiencies.

When a waiting world learned on April 12, 1955, that Jonas Salk had successfully created a vaccine to prevent poliomyelitis, he became a hero overnight. Born in a New York tenement, humble in manner, Salk had all the makings of a 20th-century icon - a knight in a white coat. In the wake of his achievement, he received a staggering number of awards and honors; for years his name ranked with Gandhi and Churchill on lists of the most revered people.

The first major bioterror event in the United States - the anthrax attacks in October 2001 - was a clarion call for scientists who work with “hot” agents to find ways of protecting civilian populations against biological weapons. In The Demon in the Freezer, Richard Preston takes us into the heart of USAMRIID, the United States Army Medical Research Institute of Infectious Diseases at Fort Detrick, Maryland, once the headquarters of the US biological weapons program and now the epicenter of national biodefense.

In 1918, a world war raged, and a lethal strain of influenza circled the globe. In the midst of all this death, a bizarre disease appeared in Europe. Eventually known as encephalitis lethargica, or sleeping sickness, it spread worldwide, leaving millions dead or locked in institutions. Then, in 1927, it disappeared as suddenly as it had arrived. Asleep, set in 1920s and '30s New York, follows a group of neurologists through hospitals and asylums as they try to solve this epidemic and treat its victims - who learned the worst fate was not dying of it, but surviving it.

The brand-new, hilarious book from best-selling, record-breaking author Adam Kay. The olden days were pretty fun if you liked wearing chainmail or chopping people's heads off, but there was one tiny little problem back then...doctors didn't have the slightest clue about how our bodies worked. It's time to find out why Ancient Egyptians thought the brain was just a useless load of old stuffing that might as well be chucked in the bin, why teachers forced their pupils to smoke cigarettes, why hairdressers would cut off their customers' legs and why people used to get paid for farting.

By investigating thousands of descriptions of epidemics reaching back before the fifth-century-BCE Plague of Athens to the distrust and violence that erupted with Ebola in 2014, Epidemics challenges a dominant hypothesis in the study of epidemics, that invariably across time and space, epidemics provoked hatred, blaming of the "other", and victimizing bearers of epidemic diseases, particularly when diseases were mysterious, without known cures or preventive measures.

For much of recorded history, people considered the heart to be the most important organ in the body. In cultures around the world, the heart—not the brain—was believed to be the location of intelligence, memory, emotion, and the soul. Over time, views on the purpose of the heart have transformed. Modern medicine and science dismissed what was once the king of the organs as a mere blood pump subservient to the brain, yet the heart remains a potent symbol of love and health and an important part of our cultural iconography.