History Medicine Science

The search to find medicines is as old as disease, which is to say as old as the human race. Through serendipity - by chewing, brewing, and snorting - some Neolithic souls discovered opium, alcohol, snakeroot, juniper, frankincense, and other helpful substances. Ötzi the Iceman, the 5,000-year-old hunter frozen in the Italian Alps, was found to have whipworms in his intestines and Bronze Age medicine, a worm-killing birch fungus, knotted to his leggings.

In Out Cold, science writer Phil Jaekl chronicles the underappreciated story of human innovation with cold, from Ancient Egypt, where it was used to treat skin irritations, to 18th-century London, where scientists used it in their first explorations of suspended animation. Throughout history, physicians have used cold to innovate life extension, enable distant space missions, and explore consciousness.

Blood carries life, yet the sight of it makes people faint. It is a waste product and a commodity pricier than oil. It can save lives and transmit deadly infections. Each one of us has roughly nine pints of it, yet many don’t even know their own blood type. And for all its ubiquitousness, the few tablespoons of blood discharged by 800 million women are still regarded as taboo: menstruation is perhaps the single most demonized biological event.

This audiobook explores big questions like these, explaining the breakthroughs and discoveries that have shaped our modern-day understanding of medicine and helped us protect and promote our health. Written in plain English, The Medicine Book cuts through the jargon and is packed with pithy explanations of the most important milestones in medical history to untangle knotty concepts.

Control is a book about what geneticist Adam Rutherford calls “a defining idea of the twentieth century.” Inspired by Darwin’s ideas about evolution, eugenics arose in Victorian England as a theory for improving the British population, and quickly spread to America. With disarming wit and scientific precision, Rutherford explains why eugenics still figures prominently in the twenty-first century, despite its genocidal past. And he confronts insidious recurring questions, revealing the intellectual bankruptcy of the idea, and the scientific impossibility of its realization.

One in ten American adults tried intermittent fasting last year, and they may be on to something. The latest research shows that fasting repairs cellular damage, improves the outcomes for chemotherapy patients, and helps with keeping a healthy weight, leading to a resurgence in recent years. Journalist Steve Hendricks’s The Oldest Cure in the World tells the history of fasting—from the ancient world (Jesus treated an epileptic with fasting) to its rediscovery centuries later.

We know it simply as "the pill", yet its genesis was anything but simple. Jonathan Eig's masterful narrative revolves around four principal characters: the fiery feminist Margaret Sanger, who was a champion of birth control in her campaign for the rights of women but neglected her own children in pursuit of free love; the beautiful Katharine McCormick, who owed her fortune to her wealthy husband, the son of the founder of International Harvester and a schizophrenic.

G. Wayne Miller has dramatically and meticulously reconstructed an amazing true story: how a group of renegade Minnesota surgeons, led by Dr. Walt Lillehei, made medical history by becoming the first doctors to operate deep inside the human heart.

Millions of us use restrictive diets, intermittent fasting, IV therapies, and Ozempic abuse to shrink until we are sample-size acceptable. But for the 30 million Americans who live with eating disorders, it isn’t just about less. More, Please is a chronicle of a lifelong fixation with food—its power to soothe, to comfort, to offer a fleeting escape from the outside world—as well as an examination of the ways in which compulsory thinness, diet culture, and the seductive promise of “wellness” have resulted in warping countless Americans’ relationship with healthy eating.

In 1968, Bruce Tucker, a Black man, went into Virginia’s top research hospital with a head injury, only to have his heart taken out of his body and put into the chest of a White businessman. Now, in The Organ Thieves, Pulitzer Prize-nominated journalist Chip Jones exposes the horrifying inequality surrounding Tucker’s death and how he was used as a human guinea pig without his family’s permission or knowledge.

In the spring of 2020, COVID-19 arrived in New York City. Before long, America’s largest metropolis was at war against a virus that mercilessly swept through its five boroughs. In The Desperate Hours, award-winning journalist Marie Brenner, having been granted unprecedented 18-month access to the entire New York-Presbyterian hospital system, tells the story of the doctors, nurses, residents, researchers, and suppliers who tried to save lives across Manhattan, Queens, and Brooklyn and the northern periphery of the city.

In The Knife Man, Wendy Moore unveils John Hunter's murky and macabre world - a world characterized by public hangings, secret expeditions to dank churchyards, and gruesome human dissections in pungent attic rooms. This is a fascinating portrait of a remarkable pioneer and his determined struggle to haul surgery out of the realms of meaningless superstitious ritual and into the dawn of modern medicine.

One hundred years after a milestone medical discovery, Insulin: The Crooked Timber tells the story of how insulin was transformed from what one clinician called "thick brown muck" into the very first drug to be produced using genetic engineering, one which would earn the founders of the US biotech company Genentech a small fortune. Taking the listener on a fascinating journey, starting with the discovery of insulin in the 1920s through to the present day, the book reveals a story of monstrous egos, toxic career rivalries, and a few unsung heroes.

Interweaving history, original reportage, and personal narrative, Pandemic explores the origin of epidemics, drawing parallels between the story of cholera - one of history's most disruptive and deadly pathogens - and the new pathogens that stalk humankind today, from Ebola and avian influenza to drug-resistant superbugs.

Pandora's Lab takes us from opium's heyday as the pain reliever of choice to recognition of opioids as a major cause of death in the United States; from the rise of trans fats as the golden ingredient for tastier, cheaper food to the heart disease epidemic that followed; and from the cries to ban DDT for the sake of the environment to an epidemic-level rise in world malaria.

At the height of World War I, history’s most lethal influenza virus erupted in an army camp in Kansas, moved east with American troops, then exploded, killing as many as 100 million people worldwide. It killed more people in twenty-four months than AIDS killed in twenty-four years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision of science and epidemic disease.

Between 1927 and 1979, more than 8,000 people were involuntarily sterilized in five hospitals across the state of Virginia. From this plain and terrible fact springs Elizabeth Catte's Pure America, a sweeping, unsparing history of eugenics in Virginia, and by extension the United States.

In 1920, at the end of the last major pandemic, global life expectancy was just over 40 years. Today, in many parts of the world, human beings can expect to live more than 80 years. As a species, we have doubled our life expectancy in just one century. There are few measures of human progress more astonishing than this increased longevity.

Transcribed from the original lectures recorded at San Francisco State University in 1987, The Nature of Drugs series highlights Shulgin’s engaging lecture style peppered with illuminating anecdotes and amusing asides. Ostensibly taught as an introductory course on drugs and biochemistry, these books serve as both a historical record of Shulgin’s teaching style and the culmination of his philosophy on drugs, psychopharmacology, states of consciousness, and societal and individual freedoms pertaining to their use, both medicinal and exploratory.

In 1953, a 27-year-old factory worker named Henry Molaison - who suffered from severe epilepsy - received a radical new version of the then-common lobotomy, targeting the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry was left profoundly amnesic, unable to create long-term memories. Over the next 60 years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.