Genetic History

James T. Costa takes listeners on a journey from Darwin's youth and travels on the HMS Beagle to Down House, his bustling home of 40 years. We accompany Darwin in his myriad pursuits against the backdrop of his enduring marriage, chronic illness, grief at the loss of three children, and joy in scientific revelation. At each chapter's end, Costa shows how we, too, can investigate the wonders of nature at work, with directions on how to re-create Darwin's experiments.

Almost daily, headlines announce newly discovered links between cancers and their genetic causes. Science journalist Jessica Wapner vividly relates the backstory behind those headlines, reconstructing the crucial breakthroughs, explaining the science behind them, and giving due to the dozens of researchers, doctors, and patients whose curiosity and determination restored the promise of a future to the more than 50,000 people diagnosed each year with chronic myeloid leukemia (CML).

Everyone has heard the story of DNA as the story of Watson, Crick, and Rosalind Franklin, but knowing the structure of DNA was only part of a greater struggle to understand life's secrets. Life's Greatest Secret is the story of the discovery and cracking of the genetic code, the thing that ultimately enables a spiraling molecule to give rise to the life that exists all around us. This great scientific breakthrough has had far-reaching consequences for how we understand ourselves and our place in the natural world.

Over more than 25 years of teaching and research, Christine Desdemaines-Hugon has become an unrivaled expert in the cave art and artists of the Dordogne region. In Stepping-Stones she combines her expertise in both art and archaeology to convey an intimate understanding of the "cave experience." Her keen insights communicate not only the incomparable artistic value of these works but also the near-spiritual impact of viewing them for oneself.

In Born in Africa, Martin Meredith follows the trail of discoveries about human origins made by scientists over the last hundred years, recounting their intense rivalry, personal feuds, and fierce controversies, as well as their feats of skill and endurance. The results have been momentous. Scientists have identified more than 20 species of extinct humans. They have firmly established Africa as the birthplace not only of humankind but also of modern humans.

Nicolelis undertakes the first attempt to explain the entirety of human history, culture, and civilization based on a series of recently uncovered key principles of brain function. This new cosmology is centered around three fundamental properties of the human brain: its insurmountable malleability to adapt and learn; its exquisite ability to allow multiple individuals to synchronize their minds around a task, goal, or belief; and its incomparable capacity for abstraction.

Charles Darwin's foremost biographer, Janet Browne, delivers a vivid and accessible introduction to the book that permanently altered our understanding of what it is to be human. A sensation on its publication in 1859, The Origin of the Species profoundly shocked Victorian readers by calling into question the belief in a Creator with its description of evolution through natural selection. And Darwin's seminal work is nearly as controversial today.

In the Rutherford and Fry's comprehensive guidebook, they tell the complete story of the universe and absolutely everything in it - skipping over some of the boring parts. It's a celebration of the weirdness of the cosmos, the strangeness of humans and the very fact that amid all the mess, we can somehow make sense of life.

Homo Deus explores the projects, dreams, and nightmares that will shape the 21st century - from overcoming death to creating artificial life. It asks the fundamental questions: Where do we go from here? And how will we protect this fragile world from our own destructive powers? This is the next stage of evolution. This is Homo Deus.

The Voyage of the Beagle - or, to give it its full title, Journal of researches into the Natural History and Geology of the Countries visited during the Voyage round the World of H.M.S. Beagle under command of Captain FitzRoy, R.N. - is much more than merely an account of Darwin's scientific observations in his 1831 - 36 travels across the globe: it is fine travel writing in its own right.

It is widely understood that Charles Darwin’s theory of evolution completely revolutionized the study of biology. Yet, according to David Sloan Wilson, the Darwinian revolution won’t be truly complete until it is applied more broadly - to everything associated with the words “human,” “culture,” and “policy.”

DNA Demystified satisfies the public appetite for and curiosity about DNA and genetics. The book begins with the basic groundwork and a brief history of DNA and genetics. Chapters then cover newsworthy topics, including DNA fingerprinting, using DNA in forensic analyses, and identifying cold-case criminals. For listeners intrigued by the proliferation of at-home DNA tests, the text includes fascinating explorations of genetic genealogy and family tree construction.

Who are we, and how did we get here? These are two of the most fundamental and far-reaching questions facing scientists and cosmologists alike and have rested at the center of human intellectual endeavor since its beginning. They are questions that stretch across numerous disciplines. Philosophy, theology, evolutionary biology, and mathematics are just some of the fields looking to explain the emergence of human life.

Most people know that Gregor Mendel, the Moravian monk who patiently grew his peas in a monastery garden, shaped our understanding of inheritance. But people might not know that Mendel's work was ignored in his own lifetime, even though it contained answers to the most pressing questions raised by Charles Darwin's revolutionary book, On Origrin of the Species, published only a few years earlier. Mendel's single chance of recognition failed utterly, and he died a lonely and disappointed man.

Sixty-six million years ago the dinosaurs were wiped from the face of the earth. Today a new generation of dinosaur hunters, armed with cutting-edge technology, is piecing together the complete story of how the dinosaurs created a hugely successful empire that lasted for around 150 million years.

It was the most radical human-breeding experiment in American history, and no one knew how it turned out. The Repository for Germinal Choice, nicknamed the Nobel Prize sperm bank, opened to notorious fanfare in 1980, and for two decades, women flocked to it from all over the country to choose a sperm donor from its roster of Nobel-laureate scientists, mathematical prodigies, successful businessmen, and star athletes.

Horses have a story to tell - one of resilience, sociability, and intelligence and of partnership with human beings. In The Horse, journalist and equestrienne Wendy Williams brings that story brilliantly to life. Williams chronicles the 56-million-year journey of horses as she visits with experts around the world, exploring what our biological affinities and differences can tell us about the bond between horses and humans and what our longtime companions might think and feel.

Viruses are the world's most abundant life form, and now, when humanity is in the midst of a close encounter with their immense power, perhaps the most feared. But do we understand viruses? Possibly the most enigmatic of living things, they are sometimes not considered a life form at all. Everything about them is extreme, including the reactions they evoke. However, for every truism about viruses, the opposite is also often true.

The early history of Earth covers such vast stretches of time that years, centuries, and even millennia become virtually meaningless. Instead, paleontologists and scientists who study geochronology divide time into periods and eras. The current view of science is that Earth is around 4.6 billion years old, and the first four billion years of its development are known as the Precambrian period.

The story of how our ancestors made the first tentative steps towards becoming human, how we lost our fur but gained language, fire and tools, and how we strode out of Africa, invented farming and cities and ultimately created modern civilisation. Where did we come from? Where are we going? Homo sapiens is the most successful, the most widespread and the most influential species ever to walk the Earth.