Understanding tDCS: Neurophysiological Insights and Clinical Applications | Neurostimulation Podcast

In this episode of the Neurostimulation Podcast, hosted by Michael Passmore, we delve into Chapter 5 of the 'Practical Guide to Transcranial Direct Current Stimulation.' The episode explores how tDCS modulates neurophysiological and functional outcomes. We discuss the neurophysiological principles behind tDCS, including various methods like TMS, EEG, fMRI, and PET for measuring its effects. The importance of state-dependent neuromodulation and personalized treatment through computational modeling is also highlighted. Finally, the episode examines the clinical implications of tDCS in conditions like stroke recovery, depression, and Alzheimer's disease. Tune in to understand how tDCS is shaping neuroscience and clinical practices.

00:00 Introduction to the Neurostimulation Podcast

00:47 Exploring Chapter Five of the tDCS Textbook

01:52 Understanding Neurophysiological Outcomes

02:34 Tools for Measuring tDCS Effects

03:41 Regional and Network Effects of tDCS

05:16 State-Dependent Neuromodulation

06:36 Modeling and Personalized Treatment

07:23 Connecting Brain Changes to Behavior

08:19 Challenges and Clinical Implications

09:07 Conclusion and Future Directions