You think metabolism is just about burning calories? Think again. What if metabolism held the key to reversing chronic disease? In this conversation, Dr. Paniz Jasbi, a leading scientist in metabolic science and personalized healthcare, joins Dr. Fab Mancini to break down what metabolism really is—and why it's so central to your health. They dive into how cutting-edge science, diagnostics, and real-world applications are transforming the way we detect and treat chronic illness. If you’ve ever struggled with energy, weight, or inflammation, this episode gives you a science-backed roadmap to healing from the inside out.

Highlights:

05:43 – What Is Metabolism, Really? Metabolism goes far beyond weight.

Dr. Jasbi defines metabolism as the sum of processes that convert energy in the body - and why understanding your unique metabolic profile is essential to disease prevention.

10:15 – Chronic Disease & Metabolic Dysfunction. Why you should care about metabolomics.

Learn how many chronic illnesses are rooted in subtle metabolic dysfunctions long before symptoms appear - and why early testing is the key.

14:20 – Data is Not Knowledge. The gap between science and real-world application.

Dr. Jasbi explains how raw data needs intelligent interpretation to become useful—and how personalized care can bridge that gap.

18:33 – Testing Beyond the Basics. Why traditional labs aren’t enough.

Discover how advanced testing methods like mass spectrometry and bioinformatics give a more accurate, personalized look at what your body needs.

22:58 – The Power of Muscle & Movement. Metabolism is influenced by lifestyle choices.

They touch on how lean muscle mass, movement, and even mental health deeply impact metabolic performance.

29:17 – From Research to Real Life. Translating science into healing.

The episode wraps with practical advice on how to advocate for yourself, interpret test results, and start making real change.

About the Guest:

Dr. Paniz Jasbi is the Co-Founder and Chief Science Officer of Theriome Inc., a pioneering health tech company at the forefront of systems biology and metabolomics. At Theriome, he leads the development of the Aristotle Test—one of the world’s most advanced metabolic assessments—designed to provide individualized insights into health, aging, and chronic disease risk using just a single drop of blood. A recognized thought leader in the integration of AI, biology, and personalized health, Dr. Jasbi joins us to discuss the future of preventative medicine, why metabolites matter more than you think, and how Theriome is building the infrastructure to end chronic disease before it begins.

Website: https://therio.me/

LinkedIn: https://www.linkedin.com/in/panizjasbi/

Youtube: https://www.youtube.com/@theriometest

Connect with Dr. Fab Mancini

www.endingchronicdisease.com

https://drfabmancini.com/

https://www.linkedin.com/in/fabmancini/

https://www.instagram.com/drfabmancini/