Cian Adams and his brother Jordan have a gene mutation which means they will almost certainly develop devastating symptoms of a rare form of frontotemporal dementia in their 40s. The same gene robbed them of their mum, Geraldine, when she was just 52, as well as their aunt, nana and other relatives.

Known as the FTD Brothers, Cian and Jordan take on epic running challenges – including a 903-mile run from John o’ Groats to Land’s End in 2024 - to raise £1 million for Alzheimer’s Research UK of which they’re ambassadors.

Helen talks to 24-year-old Cian about the family turmoil of seeing his mum suffering when he was a young boy and how he copes with the knowledge of what the future likely holds for him. He’s joined on the podcast by his girlfriend, Helen Jolly, who’s studying for a PhD in Dementia at Oxford University and gives an insight into the science behind this cruel disease.

Cian & Jordan’s mum, Geraldine.

There’s a small square of the Arctic – 3 metres by 3 metres - behind the UK Research Station in Svalbard, which Encounter Edu Founder & former teacher Jamie Buchanan-Dunlop calls his own.

Huddled in sub-zero temperatures on the ice, he’s spent hours there, broadcasting to more than 150,000 children from 57 countries, sharing the magical northernmost region of the Earth with them, bringing scientists’ work to life and inspiring young minds to understand our planet.

Encounter Edu produces live lessons for schools on some of our most pressing global issues - climate change, ocean health, the refugee crisis, Ai, and unites students living with conflict with classrooms around the world. The Encounter Edu team has reached more than 24 million youngsters in 91 countries.

UK Arctic Research Station, Svalbard

When 18-year-old Arsenal & England star Myles Lewis-Skelly showed serious potential on the pitch as a young lad, his mum Marcia experienced how confusing and lonely the world of youth football can be, and realised she needed expert knowledge for their journey ahead.

So, she studied for a Masters in Football Business and took agency exams, before setting up No1Fan.club – the UK’s first platform to help parents navigate the intricacies of the football industry, from grassroots and academy to Premier League. Marcia and her team run workshops, one-on-one sessions and talks.

Myles made history in March, becoming the youngest player to score on his England debut, and has had a ground-breaking season at Arsenal. He’s very proud of No1Fan.club and wants other children to experience the support and guidance he feels grateful to have.