Razib Khan's Unsupervised Learning Podcast Por Razib Khan arte de portada

Razib Khan's Unsupervised Learning

Razib Khan's Unsupervised Learning

De: Razib Khan
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Razib Khan engages a diverse array of thinkers on all topics under the sun. Genetics, history, and politics. See: http://razib.substack.com/ Ciencia Ciencias Biológicas Ciencias Sociales
Episodios
  • Laura Spinney: rise of the proto-Indo-Europeans
    May 17 2025
    Today Razib talks to Laura Spinney, Paris-based British author of the forthcoming Proto: How One Ancient Language Went Global. A science journalist, translator and author of both fiction and non-fiction, she has written for Nature, National Geographic, The Economist, New Scientist, and The Guardian. Spinney is the author of two novels, Doctor and The Quick, and a collection of oral history in French from Lausanne entitled Rue Centrale. In 2017, she published Pale Rider, an account of the 1918 flu pandemic. She also translated Swiss writer Charles-Ferdinand Ramuz's novel Derborence into English. Spinney graduated with a Bachelor of Science degree in Natural Sciences from Durham University and did a journalism residency at Berlin’s Planck Institute. First, Razib asks Spinney how difficult it was to integrate archaeology, linguistics and paleogenetics into her narrative in Proto, which traces the rise and proliferation of Indo-European languages from its ancestral proto-Indo-European. She talks about why this was the time to write a book like this for a general audience, as paleogenetics has revolutionized our understanding of recent prehistory, and in particular the questions around the origin of the Indo-Europeans. Razib and Spinney talk about various scenarios that have been bandied about for decades, for example, the arguments between linguistics and archaeologists whether proto-Indo-European was from the steppe or had an Anatolian homeland, and the exact relationship of the Hittites and their language to other Indo-European branches. They also delve into how genetics has helped shed light on deeper connections between some branches, like Balto-Slavic and Indo-Iranian, or Greek and Armenian. Spinney also addresses how writing a book like Proto involves placing fields like historical linguistics and archaeology with charged political associations in their proper historical context
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    1 h y 1 m
  • Bonus monologue: man the hybrid monster
    May 11 2025

    Today, Razib talks about a new paper, A structured coalescent model reveals deep ancestral structure shared by all modern humans:

    Understanding the history of admixture events and population size changes leading to modern humans is central to human evolutionary genetics. Here we introduce a coalescence-based hidden Markov model, cobraa, that explicitly represents an ancestral population split and rejoin, and demonstrate its application on simulated and real data across multiple species. Using cobraa, we present evidence for an extended period of structure in the history of all modern humans, in which two ancestral populations that diverged ~1.5 million years ago came together in an admixture event ~300 thousand years ago, in a ratio of ~80:20%. Immediately after their divergence, we detect a strong bottleneck in the major ancestral population. We inferred regions of the present-day genome derived from each ancestral population, finding that material from the minority correlates strongly with distance to coding sequence, suggesting it was deleterious against the majority background. Moreover, we found a strong correlation between regions of majority ancestry and human–Neanderthal or human–Denisovan divergence, suggesting the majority population was also ancestral to those archaic humans.

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    20 m
  • John Sailer: a time of troubles in higher education
    May 10 2025

    On this episode of the podcast Razib talks to John Sailer. Sailer is currently the director of higher education policy and a senior fellow at the Manhattan Institute. He covers issues of academic freedom, free speech, and ideological capture in higher education. Sailer has written for the Wall Street Journal, the Free Press and Tablet Magazine. Sailer holds a master’s degree in philosophy and education from Columbia University, and a bachelor’s degree in politics, philosophy, and economics from The King’s College. Prior to joining the Manhattan Institute, he was a senior fellow at the National Association of Scholars.

    Following on last week’s podcast with Jacob Shell, Razib continues to discuss the rise and fall of woke politics in academia, and the current backlash exploding out of the Trump administration. Sailer discusses his previous work back to 2020 showing how blatant universities became in their discriminatory policies against white males in particular, and how easy it was to demonstrate this dynamic with even the most minimal level of due diligence like freedom of information requests. They also discuss the reality that universities are attempting to adjust to a new landscape with the administration pressuring them to revoke DEI policies, while many faculty are urging that they instead dig in their heels. Higher education is adapting, but Sailer argues that since fundamental values have not changed, some evasion is to be expected.

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    1 h y 22 m
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