Join Drs Maureen McMahon and Karen Costenbader as they explore how diet, pollution, infections, and lifestyle factors influence lupus risk and what patients can do about it.

Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/1002127. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Systemic Lupus Erythematosus (SLE) https://emedicine.medscape.com/article/332244-overview

Risk Prediction Models for Incident Systemic Lupus Erythematosus Among Women in the Nurses' Health Study Cohorts Using Genetics, Family History, and Lifestyle and Environmental Factors https://pubmed.ncbi.nlm.nih.gov/36481507/

Association of Macronutrients and Dietary Patterns With Risk of Systemic Lupus Erythematosus in the Black Women's Health Study https://pubmed.ncbi.nlm.nih.gov/34225359/

Dietary Patterns and Risk of Systemic Lupus Erythematosus in Women https://pubmed.ncbi.nlm.nih.gov/31718449/

Alternative Dietary Indices Both Strongly Predict Risk of Chronic Disease https://pubmed.ncbi.nlm.nih.gov/22513989/

Ultra-Processed Foods: What They Are and How to Identify Them https://pubmed.ncbi.nlm.nih.gov/30744710/

Anti-dsDNA Antibodies in the Classification Criteria of Systemic Lupus Erythematosus https://pubmed.ncbi.nlm.nih.gov/35028552/

Identifying and Estimating Ultraprocessed Food Intake in the US NHANES According to the Nova Classification System of Food Processing https://pubmed.ncbi.nlm.nih.gov/36913457/

Development of a Predictive Model for Systemic Lupus Erythematosus Incidence Risk Based on Environmental Exposure Factors https://pubmed.ncbi.nlm.nih.gov/39572059/

Systemic Autoimmune Rheumatic Diseases and Multiple Industrial Air Pollutant Emissions: A Large General Population Canadian Cohort Analysis https://pubmed.ncbi.nlm.nih.gov/37068387/

Pesticide Exposure and Risk of Rheumatoid Arthritis Among Licensed Male Pesticide Applicators in the Agricultural Health Study https://pubmed.ncbi.nlm.nih.gov/28718769/

Pesticide Exposure and Risk of Systemic Lupus Erythematosus in an Urban Population of Predominantly African-American Women https://pubmed.ncbi.nlm.nih.gov/30309287/

Association of Sleep Deprivation and the Risk of Developing Systemic Lupus Erythematosus Among Women https://pubmed.ncbi.nlm.nih.gov/36094865/

Join Drs Maureen McMahon and Michael Garshick as they discuss cardiovascular disease in patients with systemic lupus erythematosus, focusing on hidden risk and challenging clinical scenarios.

Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/1002126. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Systemic Lupus Erythematosus (SLE) https://emedicine.medscape.com/article/332244-overview

Sore, Hot, and At Risk: The Emerging Specialty of Cardio-Rheumatology https://pubmed.ncbi.nlm.nih.gov/37232258/

The Bimodal Mortality Pattern of Systemic Lupus Erythematosus https://pubmed.ncbi.nlm.nih.gov/1251849/

About CDC-Funded Lupus Research https://www.cdc.gov/lupus/php/surveillance/index.html

Traditional Framingham Risk Factors Fail to Fully Account for Accelerated Atherosclerosis in Systemic Lupus Erythematosus https://pubmed.ncbi.nlm.nih.gov/11665973/

Publisher Correction: Efferocytosis Drives a Tryptophan Metabolism Pathway in Macrophages to Promote Tissue Resolution https://pubmed.ncbi.nlm.nih.gov/39285251/

Cholesterol Efflux Pathways, Inflammation, and Atherosclerosis https://pubmed.ncbi.nlm.nih.gov/34182846/

Role of Coronary Artery Calcium Score in the Primary Prevention of Cardiovascular Disease https://pubmed.ncbi.nlm.nih.gov/33947652/

Evaluation of Intima-Media Thickness and Arterial Stiffness as Early Ultrasound Biomarkers of Carotid Artery Atherosclerosis https://pubmed.ncbi.nlm.nih.gov/35362868/

Lupus Atherosclerosis Prevention Study (LAPS) https://pubmed.ncbi.nlm.nih.gov/21177297/

Colchicine in Acute Myocardial Infarction - CLEAR SYNERGY (OASIS 9) Colchicine https://www.acc.org/latest-in-cardiology/clinical-trials/2024/10/25/04/34/clear-synergy

Join Drs Maureen McMahon and Brad Rovin as they discuss the KDIGO, ACR and EULAR guidelines as they relate to lupus nephritis.

Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/1002125. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

2024 American College of Rheumatology (ACR) Guideline for the Screening, Treatment, and Management of Lupus Nephritis https://rheumatology.org/press-releases/new-acr-guideline-summary-provides-guidance-to-screen-treat-and-manage-lupus-nephritis

KDIGO 2024 Clinical Practice Guideline for the Management of Lupus Nephritis https://pubmed.ncbi.nlm.nih.gov/38182286/

EULAR 2023 Recommendations for SLE Treatment: Synopsis for the Management of Lupus Nephritis: The European Renal Association-Immunonephrology Working Group (ERA-IWG) Perspective https://pubmed.ncbi.nlm.nih.gov/37881002/

Efficacy and Safety of Voclosporin Versus Placebo for Lupus Nephritis (AURORA 1): A Double-Blind, Randomised, Multicentre, Placebo-Controlled, Phase 3 Trial https://pubmed.ncbi.nlm.nih.gov/33971155/

Podocytes https://pubmed.ncbi.nlm.nih.gov/26918173/

Can Podocytes Be Regenerated in Adults? https://pubmed.ncbi.nlm.nih.gov/28306565/

Prospective Observational Single-Centre Cohort Study to Evaluate the Effectiveness of Treating Lupus Nephritis With Rituximab and Mycophenolate Mofetil but No Oral Steroids https://pubmed.ncbi.nlm.nih.gov/23740227/

Safety of Kidney Biopsy When Performed as an Outpatient Procedure https://pubmed.ncbi.nlm.nih.gov/34077930/

Efficacy and Safety of Obinutuzumab in Active Lupus Nephritis https://pubmed.ncbi.nlm.nih.gov/39927615/

Anifrolumab in Lupus Nephritis: Results From Second-Year Extension of a Randomised Phase II Trial https://pubmed.ncbi.nlm.nih.gov/37607780/

Join Drs Maureen McMahon and Peter Izmirly as they discuss lupus epidemiology, and why knowing the data is especially important for physicians on the frontlines of healthcare.

Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/1002123. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Population-Based Incidence and Prevalence of Systemic Lupus Erythematosus: The Michigan Lupus Epidemiology and Surveillance Program https://pubmed.ncbi.nlm.nih.gov/24504809/

Update on Lupus Epidemiology: Advancing Health Disparities Research Through the Study of Minority Populations https://pubmed.ncbi.nlm.nih.gov/31436582/

Prevalence of Systemic Lupus Erythematosus in the United States: Estimates From a Meta-Analysis of the Centers for Disease Control and Prevention National Lupus Registries https://pubmed.ncbi.nlm.nih.gov/33474834/

2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus https://pubmed.ncbi.nlm.nih.gov/31383717/

CLUES Publications https://premier.ucsf.edu/california-lupus-epidemiology-study-clues

Causes of Death Among Individuals With Systemic Lupus Erythematosus by Race and Ethnicity: A Population-Based Study https://pubmed.ncbi.nlm.nih.gov/35904969/

Prevalence of Cardiovascular Events in a Population-Based Registry of Patients With Systemic Lupus Erythematosus https://pubmed.ncbi.nlm.nih.gov/39272198/

Racial and Ethnic Differences in the Prevalence and Time to Onset of Manifestations of Systemic Lupus Erythematosus: The California Lupus Surveillance Project https://pubmed.ncbi.nlm.nih.gov/31115180