In this episode of Lab Rats to Unicorns, John Flavin is joined by Dr. Kate Rubins, NASA astronaut, microbiologist, Army Major, and the first person to sequence DNA in space. With a PhD in cancer biology from Stanford and groundbreaking research on viruses like Ebola and smallpox, Dr. Rubins has spent her career at the intersection of biology, innovation, and exploration.

From her early work in infectious disease labs to running her own research facility in the Democratic Republic of Congo—and ultimately conducting over 200 experiments aboard the International Space Station—Dr. Rubins exemplifies what happens when science meets mission.

In this episode, Kate reflects on her path to becoming an astronaut (spoiler: she applied as a joke), what it’s like to conduct molecular biology experiments in microgravity, and how the constraints of space research are driving innovation in diagnostics, biotech, and health access on Earth.

Kathleen Sebelius has led a career defined by public impact—first as Governor of Kansas and then as U.S. Secretary of Health and Human Services, where she helped steer one of the most significant healthcare reforms in American history. In this episode of Lab Rats to Unicorns, Sebelius unpacks the leadership lessons she’s learned across government and health systems, including the rollout of the Affordable Care Act and her efforts to accelerate translational research through federal agencies like the NIH, FDA, and CMS.

At a time when NIH funding is under political pressure, Sebelius offers a powerful defense of continued public investment in biomedical science. She argues that undermining NIH not only risks slowing innovation but jeopardizes America’s global leadership in medicine, biotechnology, and economic competitiveness.

Whether you're a policymaker, entrepreneur, or scientist, this conversation reveals why bipartisan support for public health infrastructure and regulatory expertise is more important than ever—and how real progress depends on collaboration across sectors.

In this episode of Lab Rats to Unicorns, host John Flavin speaks with Dr. Geoff Duyk, co-founder and CEO of Grove Biopharma. Geoff brings over 35 years of experience across academia, biotech leadership, and venture capital. From his early work in human genetics at UCSF to co-founding Millennium Pharmaceuticals and leading R&D at Exelixis, Geoff unpacks the evolution of biotech from the 1970s to today.

This conversation comes on the heels of Grove’s massive $30M Series A. Geoff shares the story behind Grove Biopharma’s founding, born from a collaboration between a Northwestern chemist, a green chemistry innovator, and himself—culminating in a startup focused on intracellular targets using novel protein-mimetic polymers. Geoff also reflects on the infrastructure and cultural foundations that make biotech innovation possible, from the NIH’s visionary investments to the importance of people, timing, and place. Learn how Grove is challenging the limits of drug design with a new class of molecules that behave like antibodies but operate inside cells—unlocking new frontiers in cancer and beyond.