Distributed Shock - Sepsis/Septic Shock
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Distributed Shock - Sepsis/Septic Shock
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In this educational episode of IM Basic, Drs. Eric Acker and Tark break down the complex topic of septic shock for PGY1 residents and medical students. They explore the pathophysiology, clinical presentation, and diagnostic challenges of septic shock, emphasizing the importance of recognizing atypical signs like hypothermia and bradycardia. The discussion covers essential labs (lactate, procalcitonin), imaging strategies, and the role of scoring systems like SOFA and qSOFA.
Key treatment principles are unpacked, including individualized fluid resuscitation, the timing and selection of vasopressors like norepinephrine (Levophed), and nuanced antibiotic stewardship tailored to suspected pathogens and resistance patterns. The hosts also highlight the importance of source control and the dangers of mimics like DKA and thyroid storm. This is a must-listen for those looking to build a solid clinical foundation in managing septic shock.
Citations & References:
- PulmCrit - Septic Shock
- Surviving Sepsis Campaign Guidelines (2021)
- Sepsis-3 Definitions [Singer et al., JAMA. 2016]
- VANISH Trial (Gordon et al., JAMA. 2016)
- CAT Trial [Annane et al., Crit Care Med. 2007]