This is a Radio Cherwell original podcast

Hosted by: Aleksandra Jedinska

Listen Live: radiocherwell.com

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About this episode of Science & Beyond

Heart disease is the UK’s biggest killer — taking over 170,000 lives every year, even edging out cancer. In this debut episode of the series, we’re diving headfirst into cardiology: a topic that affects nearly every family, yet often remains shrouded in medical jargon. With help from our two expert guests — Tae and Rebecca — we unpack what really goes wrong when the heart falters.

From the ‘plumbing’ and ‘electrics’ of the heart to what actually happens during a myocardial infarction, we break down the life-or-death moments clinicians face every day. You’ll hear about ECGs, emergency treatments, and the silent build-up of risk factors like smoking, high cholesterol, diabetes, and hypertension. We also explore the science behind cholesterol-lowering drugs — statins, ezetimibe, and even PCSK9 inhibitors — and look at interventions like ablations for arrhythmias and managing heart failure.

And yes — even oral hygiene matters. You’ll learn how a simple dental infection can lead to endocarditis, and why the aortic valve is often the one to watch. Whether you’re a future medic or just want to understand the heart that keeps you going, this episode sets the pace for a season full of science, stories, and life-saving insights.

This is a Radio Cherwell original podcast

Hosted by: Aleksandra Jedinska

Listen Live: radiocherwell.com

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About this episode of Science & Beyond

In this episode, we meet Riyanshi, a first-year medical student at the University of Manchester, who shares a vivid snapshot of life at medical school — from navigating weekly case-based learning to practising consultation skills with professional actors.

We explore how the course blends theory and clinical preparation from day one, with modules in physiology and pharmacology alongside anatomy taught through full-body dissections — a surreal yet deeply meaningful experience, marked by the school’s reflective ‘Service of Thanksgiving’ to honour donors.

Riyanshi’s favourite topic, asthma, is personal — as someone who lives with the condition, learning about its pathophysiology has made the science come alive. We also dive into the pharmacology of hypertension, where she breaks down the mechanisms behind first-line treatments like amlodipine, which reduces stroke volume by decreasing cardiac contractility, and Ramipril, an ACE inhibitor that lowers blood volume through diuresis.

Beyond the classroom, we look at the journey ahead: from medical licensing exams to life as a junior doctor. Riyanshi also shares what makes Manchester special — from its industrial heritage to the symbolic worker bee seen across the city. This episode is a grounded and inspiring look at the making of a future doctor.

This is a Radio Cherwell original podcast

Hosted by: Aleksandra Jedinska

Listen Live: radiocherwell.com

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About this episode of Science & Beyond

In this episode, I’m joined by an Oxford master's student at the cutting edge of medical research. We dive into the fascinating world of induced pluripotent stem cells (iPSCs) — a revolutionary discovery by Nobel prize-winning Shinya Yamanaka that turned the scientific world on its head.

By introducing a specific set of transcription factors, ordinary somatic cells like skin cells can be reprogrammed into stem cells capable of transforming into virtually any cell type — including neurons. Together, we explore the different types of stem cells — from totipotent to pluripotent to multipotent — and their unique roles in regenerative medicine and neuroscience.

Our guest shares insights from her research with neurones, and how it could contribute to palliative care. We also compare the path to medical school in America vs. the UK, and how she found herself in Oxford, chasing answers in one of the most complex frontiers of modern medicine.

Whether you're a budding scientist or just curious about where the future of medicine is heading, this conversation brings stem cell science down to earth — and might just blow your mind.