Hypertension: A Mathematical Endorsement for Treatment
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Hypertension: A Mathematical Endorsement for Treatment
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This review article mathematically endorses lowering blood pressure (BP) as a highly effective treatment for hypertension, which is the leading cause of global mortality. It highlights the strong concordance between the expected benefits of BP reduction observed in cohort studies and the actual benefits documented in randomized controlled trials (RCTs). The authors advocate for clinicians and guideline committees to consider lower BP thresholds for diagnosing and treating hypertension to substantially reduce the worldwide burden of cardiovascular disease (CVD), emphasizing that treatment benefits significantly outweigh potential adverse effects. Despite the compelling evidence, current diagnostic and treatment goals for hypertension still vary widely across international guidelines, indicating a need for more aggressive and unified strategies to improve global BP control.