In this episode, Vic speaks with Mark Durante, founder of RiseUP Medical, about the cutting-edge world of biologics and regenerative medicine. They explore how biologics like PRP, PRF, stem cells, and exosomes are being applied in areas such as neuropathy, orthopedic injuries, aesthetics, and sexual health. Mark explains the science behind cell therapies, including mesenchymal stem cells and Wharton's Jelly, and discusses RiseUP’s role in bridging labs and physicians to expand treatment options. They also review recent peer-reviewed studies focused on diabetic and chemo-induced neuropathy and discuss how regenerative treatments may complement or reduce the need for pharmaceuticals and surgery. Mark shares his personal journey from heart failure and near-disability to recovery through biologics, turning his experience into a mission to advance access and innovation in this space.

Rize UpMedical: website

Mark Durante: LinkedIn

Published Research discussed in the show:

• Exploring the Role of Mesenchymal Stem Cell–Derived Exosomes in Diabetic and Chemotherapy‐Induced Peripheral Neuropathy, Molecular Neurobiology (2024).
• Improvements in Diabetic Neuropathy with Topical Human Mesenchymal Stem Cell Conditioned Media, American Journal of Biomedical Science & Research (2024).
• Wharton’s Jelly Tissue Allograft for Connective Tissue Defects Surrounding Nerves in the Tarsal Tunnel: A Retrospective Case Series, Reports by MDPI (2024).

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In this episode, Vic and Marcus cover a sweeping range of major developments in healthcare, policy, and the economy. They dive deep into the UnitedHealth Group crisis, discussing the CEO resignation, DOJ investigation, and stock collapse. They analyze inflation data, Microsoft layoffs, and U.S.-China trade pauses, while also breaking down emerging trends in biotech, AI-driven drug development, hospital discharge tech, and venture capital movement. The hosts explore RFK Jr.'s impact on CMS policy, Medicaid cuts, Roundup controversies, IPO market challenges, and gene-editing breakthroughs—all framed by their signature lens on innovation, impact, and policy shifts.

Links:

6:13 - Surprise U.S.-China Trade Deal Gives Global Economy Reprieve WSJ

9:07 - Mild April Inflation Captures Early Stages of Tariff Effects WSJ

9:57 - Microsoft Slashing Thousands of Workers, Including Management Jobs WSJ

11:16 - Clarium lands $27M to fortify hospital supply chains Axios

12:09 - Olio Secures $11M to Scale Care Coordination Platform HIT

13:30 - J&J, Eli Lilly join $85M financing for newly unveiled gene editing biotech Stylus Fierce Healthcare

15:19 - Somite, a developer of foundation models for the human cell, raised $47m in Series A. X

16:35 - Cohere Health lands $90M series C round to expand AI use cases Fierce Healthcare

17:24 - Pathos AI raises $365M at $1.6B valuation Axios

18:21 - State of Private Markets: Q1 2025 Carta

23:07 - CMS proposes crackdown on 'money laundering' provider tax policies Modern Healthcare

24:25 - Drugmakers Avoid Worst-Case Pricing Scenario for Now WSJ

25:14 - Trump Leadership: If You Want Welfare and Can Work, You Must NYT-Op

28:15 - $715B Medicaid cut passes House committee in reconciliation bill Healthcare Finance

30:23 - Trump Officials Balk at RFK Jr.’s Attack on Pesticides WSJ

31:17 - CMS Innovation Center Strategy to Make America Healthy Again CMS website

36:48 - UnitedHealth CEO Is Out, Sending Shares Plummeting WSJ

40:08 - UnitedHealth Group Is Under Criminal Investigation for Possible Medicare Fraud WSJ

51:25 - Kaiser Permanente sees 16.1% year-over-year Q1 revenue growth following Risant acquisitions Fierce Healthcare

51:46 - Omada Health Files to Go Public: Will It Be Successful? MedCity

53:06 - Eli Lilly Says Trial Patients Lost More Weight on Zepbound Than Rival’s Wegovy WSJ

53:44 - Bayer Shares Jump After Results Beat Expectations on Pharma Strength WSJ

54:10 - GSK Makes a Big Liver Disease Move With $1.2B Deal for Phase 3-Ready MASH Drug 54:10 - MedCity News

54:57 -

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In this episode, Vic Gatto and guest host Rick Abramson, a physician and healthcare strategist, cover the latest in AI regulation, economic indicators affecting healthcare, recent venture deals in senior living and food-as-medicine startups, and growing momentum behind the MAHA (Make America Healthy Again) movement. They discuss controversial federal appointments, shifts in FDA policy, the balance between prevention and treatment, Medicare Advantage fraud allegations, state Medicaid funding loopholes, drug manufacturing regulation, and pressures facing the nursing workforce and academic medical centers.

Previous Guest Show:

#73 - AI and Healthcare Innovation: A Conversation with Dr. Rick Abramson YouTube

Links

3:27 - U.S. nonfarm jobs grow by 177,000 in April, beating expectations UPI

4:28 - Powell rules out a preemptive rate cut to blunt any tariff impact CNBC

6:12 - U.S. and U.K. Unveil Framework for Trade Deal WSJ

7:09 - U.S. and Chinese Officials to Meet for Trade Talks WSJ

8:08 - TSOLife Secures $43M to Revolutionize Senior Living Experience HIT

10:11 - FoodHealth Company corrals $7.5M Series A to support pivot Axios

12:03 - Deerfield Management raises $600M fund in "constrained" market Axios

12:53 - Trump Picks a ‘MAHA’ Movement Leader for Surgeon General WSJ

13:38 - Biotech Stocks Fall After FDA Names Vinay Prasad To Succeed Marks at CBER BioSpace

34:31 - Justice Department Sues Big Medicare Insurers Alleging Kickbacks WSJ

36:20 - G.O.P. Targets a Medicaid Loophole Used by 49 States to Grab Federal Money NYT

41:07 - Trump orders FDA to help speed building of new drug factories Healthcare Dive

42:16 - N.I.H. Bans New Funding From U.S. Scientists to Partners Abroad NYT

44:20 - U.S. to Overhaul Curbs on AI Chip Exports After Industry Backlash WSJ

45:45 - CVS Beats Wall Street Expectations, Plans to Withdraw From ACA Business WSJ

47:22 - Clover Heath raises guidance, revenue jumps 33% Fierce Healthcare

48:29 - Vanderbilt Medical Center implements hiring freeze, layoffs amid federal funding cuts WTVF

50:33 - OHSU, Legacy Health's 10-hospital, $8B merger is no more Fierce Healthcare

52:37 - Helping nurse managers tend to their frontline workers Fierce Healthcare

53:28 - Nurse managers: The backbone of a strong nursing workforce McKinsey Report

56:38 - Virtual MSK provider IncludeHealth rebrands as LainaHealth supercharged with AI and computer vision Fierce Healthcare

57:04 - Health reports Q1 growth Axios

1:00:07 - Hims & Hers' Q1 revenue doubles to $586M, boos

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In this episode, Vic and Marcus cover a wide range of pressing topics including layoffs at UPS, economic instability, and the implications of AI in healthcare and commerce. They discuss new AI-powered voice agents from companies like Zocdoc and Cedar, explore the role of Meta and surveillance technology, and criticize loose AI guardrails on social platforms. The hosts also examine AI’s impact on the audit and pharmaceutical sectors, M&A activity, and the growing use of GLP-1 drugs by athletes. The episode closes with a powerful conversation on mental health, residency burnout, and the suicide crisis among young doctors

Links

3:43 - U.S. Economy Shrank in First Quarter as Imports Surged Ahead of Tariffs WSJ

5:39 - U.S. Hiring Slows as Employers’ Concerns Mount, ADP Data Show WSJ

7:07 - UPS to Cut 20,000 Jobs After Amazon Breakup WSJ

8:15 - Beijing Doesn’t Want America to See Its Trade-War Pain WSJ

10:27 - Canada’s Election Challenges Trump’s Theory of Trade War WSJ

12:25 - Plenful Raises $50M in Series B Funding FINSMES

13:24 - HealthPlan Data Solutions Secures $15M With MK Capital CityBiz

14:25 - Trek gets $11M to unlock health care's pricing black box Axios

15:37 - Blooming Health raises $26M for social services access Axios

17:06 - Senators introduce RPM Access Act to increase rural payment rate for remote monitoring Fierce Healthcare

18:19 - Supreme Court rules against hospitals in DSH case Modern Healthcare

19:37 - CMS explores limiting insurers' use of prior authorizations Modern Healthcare

21:16 - Humana bucks Medicare Advantage cost trend Modern Healthcare

22:20 - Backstopped by Q1 overperformance, Tenet Healthcare will stay aggressive amid policy uncertainties Fierce Healthcare

23:09 - UHS sees behavioral health volumes drop in Q1 Healthcare Dive

24:26 - Teladoc Health acquires UpLift for $30M, doubling down on virtual mental health despite BetterHelp's struggles Fierce Healthcare

26:20 - Novartis to buy Regulus Therapeutics for up to $1.7B Axios

27:25 - Pfizer Expands Cost-Cutting Measures, Reaffirms Outlook WSJ

28:05 - Hims & Hers, Novo Nordisk partner on GLP-1s Modern Healthcare

32:09 - Merck to Spend $1 Billion on New Factory to Make U.S. Supplies of Blockbuster Drug WSJ

33:21 - Amateur Athletes Are Turning to Ozempic to Raise Their Game WSJ

35:01 - Suicide Reverberates Among Young Doctors WSJ

41:31 - Cedar rolls out AI voice agent to tackle patients' medical billing questions Fierce Healthcare

43:46 - Zocdoc launches voice AI agent Zo to streamline bookings by phone Fierce Healthcare

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In this episode, Vic sits down with Ben Lytle, founder of Anthem and serial entrepreneur, to discuss the future of healthcare, including AI’s role in solving clinician shortages, the creation of SilverSneakers, and how lifestyle changes can tackle chronic disease. They also cover healthcare system reform, the importance of bounded AI for clinical accuracy, leadership strategies, and how individuals can prepare for rapid societal shifts by building health, financial resilience, and a sense of purpose.

Ben’s website: Link

Ben’s Books

• The Potentialist I: Your Future in the New Reality of the Next Thirty Years
• The Potentialist II: The Pursuit of Wisdom

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In this episode, Vic and Marcus cover a wide range of topics including the current state of the U.S. economy, rising tensions and negotiations around tariffs between the U.S. and China, the volatility of the housing market, and recent VC activity across healthcare, nutrition, and biotech. They discuss the Greater Nashville Private Capital Association event, trends in venture capital funding, the impact of political decisions on biotech innovation, Medicaid policy changes, the attack on PBMs, retail pharmacy challenges, healthcare earnings updates, and developments in AI regulation and corporate actions.

Links

3:32 - - Fed, Tariff Fears Send Dow Down More Than 900 Points WSJ

4:02 - Tech Shares Drive Stocks Higher for a Third Straight Session WSJ

4:52 - White House Considers Slashing China Tariffs to De-Escalate Trade War WSJ

6:44 - Bessent says China tariffs are not sustainable as US signals willingness to de-escalate Reuters

7:23 - DHL Suspends High-Value Deliveries to U.S. Consumers Amid Tariff Turmoil WSJ

9:06 - Home Sales in March Fell 5.9%, Biggest Drop Since 2022 WSJ

11:27 - Gold Hits $3,500, Setting Another Record, as Investors Remain Uneasy NYT

13:11 - Nutrition counseling startup Nourish clinches $70M to expand services Fierce Healthcare

14:03 - Healthee lands $50M to streamline benefits Axios

15:20 - Superpower scores $30M to offer personalized health testing Fierce Healthcare

17:58 - Overture Life raises $20.6M for IVF automation Axios

19:38 - HCA veterans raise $10 million to launch PathPoint Health NBJ

21:08 - Biolinq raises $100M Series C for glucose monitoring device Axios

22:11 - Trump’s FDA Sends a Bullish Signal to Biotech WSJ

24:39 - The True Origins of Covid-19 White House

31:30 - Congressional Republicans signal on Medicaid cuts HFMA

34:17 - RFK Jr. Unveils Plan to Phase Out Artificial Food Dyes WSJ

36:02 - In a reversal, the Trump administration restores funding for women's health study NPR

37:12 - Arkansas governor signs bill banning PBMs from owning pharmacies Healthcae Finance

39:34 - Arkansas PBM law could spur lookalike restrictions Axios

39:42 - Judge Rules Google Operates Illegal Ad Monopoly WSJ

42:20 - Justice Department Urges Tough Action to Break Google’s Search Dominance WSJ

46:19 - A Startling Admission From a G.O.P. Senator: ‘We Are All Afraid’ NYT

50:13 - Elevance Health execs seek to ease Wall Street's concerns about elevated MA costs Fierce Healthcare

52:56 - Centene boosts revenue guidance for 2025 as it brings in $

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In this episode, Marcus and Vic break down a whirlwind week across healthcare, policy, economics, and AI. They cover the volatile market reaction to trade tensions and Jerome Powell’s inflation warnings, the downturn in healthcare stocks and payor performance, and continued disruption in the hospital sector. They examine critical funding cuts at HHS, CMS policy shifts, and policy changes affecting food stamps and Medicaid waivers. The conversation also touches on investment rounds in health tech, Mark Cuban’s take on drug pricing, antitrust actions against tech giants, California’s challenge to federal tariffs, and a surprising rise in autism rates. In AI news, they review Claude’s Gmail integration, OpenAI’s improved memory, and Nvidia’s strategy in the U.S. Vic and Marcus end with a reflection on Daniel Kahneman’s death and the ethics of aging and end-of-life care.

Links

1:08 - Trade Tensions Weigh Down Nvidia, Tech Stocks WSJ

2:40 - Powell Warns of ‘Challenging Scenario’ for Fed as Trade War Rages WSJ

6:50 - NY Fed: Business Leaders Survey for April New York Fed

9:52 - China Halts Critical Exports as Trade War Intensifies NYT

13:51 - What the Weak Dollar Means for the Global Economy WSJ

15: 08 - Brellium snags $16.7M Series A to use AI on patient charts Axios

15:52 - PolicyMe announces $30 million CAD in funding Coverager

16:35 - Deacon Health Launches bringing Tech-Enabled Care Coordination to Specialty Care Businesswire

17:26 - Chapter, a Medicare startup with links to Vance, Thiel, and Ramaswamy, just raised a round at $1.5B valuation TechCrunch

18:19 - Hellocare.ai scores $47M for AI-enabled virtual care for smart hospitals Mobi Health

19:18 - Attovia Therapeutics raises $90M to treat autoimmune diseases Axios

20:00 - HHS funding slashed by 30 percent in budget proposal Politico

21:01 - CMS proposes 2.4% bump to inpatient pay in fiscal 2026, calls for deregulation, MAHA suggestions Fierce Healthcare

23:05 - USDA Is Fast-Tracking Requests to Yank Soda From Food-Stamps Program WSJ

23:51 - CMS to end federal match for states’ Medicaid funding requests Fierce Healthcare

27:07 - Trump targets health care costs with executive order on drug price negotiations, hospital payments Stat

28:55 - Mark Cuban: EO on healthcare and drug pricing could save hundreds of billion X

31:21 - What to Know About Trump’s Antitrust Efforts Against Tech Giants NYT

32:27 - Inside Mark Zuckerberg’s Failed Negotiations to End Antitrust Case WSJhttps://bit.ly/4iuwwpl

34:11 - Japan Regulator Orders Google to Stop Anticompetitive Practices WSJ

35:13 - Google Faces Potential $6.6 Billion U.K. Antitrust Lawsuit Over Search Advertising WSJ

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In this episode of the Health Further podcast, hosts Vic and Marcus sit down with former U.S. Senate Majority Leader and heart transplant surgeon, Senator Bill Frist, to explore the intersection of environmental policy, healthcare, and innovation. Senator Frist discusses his role as Global Board Chair of The Nature Conservancy and why climate change and biodiversity loss are now the greatest threats to human health. He shares stories from his recent trip to the Amazon, the medical breakthroughs enabled by nature, and how depolarizing political issues is key to scalable solutions. They dive into healthcare’s role in emissions, the need for planetary and human health integration, and how medical education must adapt to address climate-linked diseases and health crises.

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