Episodios

  • A Daily Pill for Dog Lymphoma? The Promise of Monepantel Explained | Kim Agnew, BVSc #287

    A Daily Pill for Dog Lymphoma? The Promise of Monepantel Explained | Kim Agnew, BVSc #287
    Jul 7 2025
    Originally aired in 2023, Molly Jacobson interviews Dr. Kim Agnew about the groundbreaking trials of Monepantel, a sheep dewormer repurposed as a potential treatment for canine lymphoma. Discover the science behind this innovative therapy, its potential to stabilize lymphoma, and how it compares to traditional treatments like chemotherapy and prednisone. Key Topics: What is Monepantel, and how was it discovered? The mechanism behind Monepantel's ability to target cancer cells. Early trial results: Quality of life and stability for dogs with B-cell lymphoma. How Monepantel compares to prednisone and chemotherapy. Insights into ongoing and future clinical trials. How dog lovers can participate in studies. Your Voice Matters! If you have a question for our team, or if you want to share your own hopeful dog cancer story, we want to hear from you! Go to https://www.dogcancer.com/ask to submit your question or story, or call our Listener Line at +1 808-868-3200 to leave a question. Related Videos: https://www.youtube.com/watch?v=_92w6TTXM5c https://www.youtube.com/watch?v=uAZrPM1X8ww Related Links: PharmAust Dog Lymphoma Clinical Trial: https://www.pharmaust.com/petdogtrial/ Chapters: 00:00 Introduction 00:30 Meet Dr. Kim Agnew and Monepantel Overview 01:15 The Origin of Monepantel: From Dewormer to Cancer Fighter 03:30 How Monepantel Targets Cancer Cells 07:00 Insights on Clinical Trials for Canine Lymphoma 09:30 Benefits of Monepantel: A Daily Pill for Dogs 12:00 Comparing Monepantel to Chemotherapy and Prednisone 14:45 Early Trial Results: Stabilizing Lymphoma in Dogs 18:30 Why Lymphoma Was Chosen for Trials 20:00 Potential for Treating Other Cancers in Dogs 23:15 How to Enroll Dogs in Clinical Trials 26:45 Side Effects and Safety of Monepantel 31:00 Future Trials and Research Goals 34:30 Closing Thoughts and Resources 33:55 Closing Remarks and Resources Get to know Kim Agnew, BVSc: https://www.dogcancer.com/people/kim-agnew-bvsc/ For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/ Learn more about your ad choices. Visit megaphone.fm/adchoices
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    48 m
  • How Some Dogs Get Cancer: How Genetic Mutations Trigger Cancer in Dogs | Charlotte Hacker, MS, PhD #286

    How Some Dogs Get Cancer: How Genetic Mutations Trigger Cancer in Dogs | Charlotte Hacker, MS, PhD #286
    Jun 23 2025
    Dr. Charlotte Hacker discusses the complex genetics behind why dogs get cancer. Despite common beliefs, larger animals like elephants and blue whales rarely get cancer due to high levels of tumor suppressor genes like p53. Unfortunately, dogs' genetic makeup, influenced by rapid, human-directed breeding practices, makes them particularly susceptible to cancer. Dr. Hacker explains the role of DNA, mutations, proto-oncogenes, and tumor suppressor genes in cancer development. She emphasizes variability across breeds, hereditary and spontaneous mutations, and environmental factors like UV light. Preventive measures for genetic and spontaneous mutations in dogs, common cancer-related genes in different breeds, and the promise of emerging research in fields like epigenetics are also discussed. Your Voice Matters! If you have a question for our team, or if you want to share your own hopeful dog cancer story, we want to hear from you! Go to https://www.dogcancer.com/ask to submit your question or story, or call our Listener Line at +1 808-868-3200 to leave a question. Related Videos: https://youtu.be/uBCRRQyaTgE https://www.youtube.com/watch?v=Q7Wvo9IjcvA https://www.youtube.com/watch?v=VlkWnaCYvfU Related Links: Genetic Mutations and Dog Cancer: An Overview (article) https://www.dogcancer.com/articles/stats-and-facts/genetic-mutations-and-dog-cancer/ Chapters: 00:00 Introduction 00:21 Meet Dr. Charlotte Hacker 01:09 Understanding Dog Genetics 03:06 DNA and Its Role in Cancer 06:48 Mutations and Their Effects 18:43 Oncogenes and Tumor Suppressors 24:14 Preventing Mutations in Dogs 25:49 Conclusion and Resources 33:55 Closing Remarks and Resources Get to know Charlotte Hacker: https://www.dogcancer.com/people/charlotte-hacker-ms-phd/ For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/ Learn more about your ad choices. Visit megaphone.fm/adchoices
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    31 m
  • Dog Cancer Success Story: Dunbar's Triumph Over Lung Cancer | Dr. Katie Berlin and Tara Diehl #285

    Dog Cancer Success Story: Dunbar's Triumph Over Lung Cancer | Dr. Katie Berlin and Tara Diehl #285
    Jun 9 2025
    Meet Tara Diehl and Dr. Katie Berlin and soak in hope and love as they discuss the inspiring story of Dunbar, Tara’s 12-year-old dog diagnosed with primary undifferentiated pulmonary carcinoma. From the initial harrowing diagnosis to numerous treatments, including surgery, chemotherapy, and the promising effects of Palladia, Dunbar's story is a testament to hope, resilience, and the power of a dedicated dog mom … and dog insurance! The discussion highlights the importance of pet insurance, holistic care approaches, and the invaluable bond between pets, their owners, and veterinary teams. Your Voice Matters! If you have a question for our team, or if you want to share your own hopeful dog cancer story, we want to hear from you! Go to https://www.dogcancer.com/ask to submit your question or story, or call our Listener Line at +1 808-868-3200 to leave a question. Related Links: Dog Cancer Survival Guide - https://dogcancerbook.com/ Apocaps – https://apocaps.com/ Chapters: 00:00 Living in the Moment: Dunbar's Journey Begins 01:03 The Diagnosis: A Vet Tech's Worst Fear 03:18 Dunbar's Personality Shines Through 06:19 The Battle with Cancer: Treatment and Hope 08:52 Insurance and Financial Relief 14:04 A Comprehensive Approach: Supplements and Alternative Therapies 17:16 Dunbar's Resilience and Joy 18:09 Dog Cancer Resources and Support 18:38 The Impact of Attitude on Treatment 19:10 Dunbar's Medical Journey 23:57 Dunbar's Miraculous Recovery 25:26 Dunbar's Current Life and Activities 26:40 The Emotional Bond with Veterinary Teams 29:47 Final Thoughts and Encouragement 33:55 Closing Remarks and Resources Get to know Dr. Katie Berlin: https://www.dogcancer.com/people/katie-berlin-dvm/ Get to know Tara Diehl: https://www.dogcancer.com/people/tara-diehl/ For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/ Learn more about your ad choices. Visit megaphone.fm/adchoices
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    41 m
  • Insider Look at Rabacfosadine (Tanovea) from Shelved Human Drug to Dog Lymphoma Treatment | Dr. Doug Thamm #284

    Insider Look at Rabacfosadine (Tanovea) from Shelved Human Drug to Dog Lymphoma Treatment | Dr. Doug Thamm #284
    May 26 2025
    Dr. Doug Thamm discusses the development and use of Tanovea, a drug for treating lymphoma in dogs. He explains the drug's origins, initially researched as a human cancer therapeutic in collaboration with Gilead Sciences, and its transition to veterinary use. Dr. Thamm provides insights into Tanovea’s application, dosage, and effectiveness compared to the CHOP protocol, as well as its potential side effects and other possible uses in different cancer types like multiple myeloma. The episode also delves into related immunotherapy research and personal reflections from Dr. Thamm, a double cancer survivor, on his career choice in veterinary oncology. Your Voice Matters! If you have a question for our team, or if you want to share your own hopeful dog cancer story, we want to hear from you! Go to https://www.dogcancer.com/ask to submit your question or story, or call our Listener Line at +1 808-868-3200 to leave a question. Related Videos: https://www.youtube.com/watch?v=G0iRyKshzq8 Related Links: Our article on lymphoma: https://www.dogcancer.com/articles/types-of-dog-cancer/lymphoma-in-dogs/ Our article on Tanovea: https://www.dogcancer.com/articles/drugs/tanovea-rabacfosadine-chemotherapy/ Get the facts on dog cancer remission: https://www.dogcancer.com/articles/stats-and-facts/dog-cancer-remission/ Chapters: 00:00 Introduction 00:13 Interview with Dr. Doug Thamm 00:26 The Early Involvement with Tanovea 00:41 Challenges and Discoveries in Drug Development 02:16 Transition from Human to Veterinary Use 02:48 Clinical Trials and Dosage Experiments 06:45 FDA Approval and Practical Use 08:05 Comparing Tanovea and CHOP Protocol 15:23 Exploring Alternative Treatments: Laverdia 18:43 Off-Label Uses and Future Research 23:46 Exploring Tanovea's Effectiveness in Blood Cancers 25:14 Cost Comparison: Tanovea vs. CHOP 26:15 Side Effects of Tanovea 28:47 Pulmonary Fibrosis and Breed-Specific Risks 32:52 Personal Cancer Journeys: Dr. Doug and His Wife 38:23 Debunking Myths About Dog Cancer Treatment 42:24 The Future of Cancer Treatment: Immunotherapy 45:23 Conclusion and Resources Get to know Dr. Doug Thamm: https://www.dogcancer.com/people/doug-Thammm-v-m-d-diplomate-acvim-oncology/ For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/ Learn more about your ad choices. Visit megaphone.fm/adchoices
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    51 m
  • Healing Herb or Overly Hyped -- Can CBD Cure Dog Cancer? | Dr. Narda Robinson #283

    Healing Herb or Overly Hyped -- Can CBD Cure Dog Cancer? | Dr. Narda Robinson #283
    May 12 2025
    Dr. Narda Robinson dives into the usage of cannabis for dogs with cancer, including: Anti-inflammatory and pain control benefits Potential anti-cancer effects Concerns about long-term usage The discussion also highlights the importance of product quality, potential herb-drug interactions, environmental considerations, and the legal constraints veterinarians face. Dr. Narda Robinson shares her insights on when and how to use cannabis products effectively, including the importance of combining them with other integrative modalities for the well-being of the dog. Your Voice Matters! If you have a question for our team, or if you want to share your own hopeful dog cancer story, we want to hear from you! Go to https://www.dogcancer.com/ask to submit your question or story, or call our Listener Line at +1 808-868-3200 to leave a question. Related Links: Our CBD article: https://www.dogcancer.com/articles/supplements/cbd-for-dogs-with-cancer/ Check out our knowledgebase of supplements! https://www.dogcancer.com/supplements/ Chapters: 00:00 Introduction 00:13 Welcome to Dog Cancer Answers 00:38 Cannabis and Cancer: Anti-Inflammatory Benefits 02:48 Environmental Impact of Cannabis Cultivation 08:04 Using Cannabis for Dogs with Cancer 10:37 CBD and Drug Interactions 16:07 Non-Pharmacological Approaches to Healing 29:02 Legal Considerations for Veterinarians 35:55 Conclusion and Final Thoughts Get to know Dr. Narda Robinson: https://www.dogcancer.com/people/narda-g-robinson-do-dvm-ms-faama/ For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/ Learn more about your ad choices. Visit megaphone.fm/adchoices
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    37 m
  • What Does CBD Do for Dogs? This Cannabis Researcher Navigates the Controversy | Dr. Narda Robinson #282

    What Does CBD Do for Dogs? This Cannabis Researcher Navigates the Controversy | Dr. Narda Robinson #282
    Apr 28 2025
    Dr. Narda Robinson, a human doctor AND a veterinarian, discusses the history and medicinal applications of CBD and THC, particularly in veterinary medicine. Focusing on her pioneering work at Colorado State University, she shares insights into the challenges and benefits of researching cannabis for canine health. Topics covered: The endocannabinoid system The differences between THC and CBD Quality control issues The broader implications of using cannabis derivatives for conditions like epilepsy and pain management in dogs. The potential of integrating cannabinoids into veterinary practices Common misconceptions and safety concerns Your Voice Matters! If you have a question for our team, or if you want to share your own hopeful dog cancer story, we want to hear from you! Go to https://www.dogcancer.com/ask to submit your question or story, or call our Listener Line at +1 808-868-3200 to leave a question. Related Links: Our CBD article: https://www.dogcancer.com/articles/supplements/cbd-for-dogs-with-cancer/ Check out our knowledgebase of supplements! https://www.dogcancer.com/supplements/ Chapters: 00:00 Introduction 00:21 Guest Introduction: Dr. Narda Robinson 00:30 The Rise of CBD in Veterinary Medicine 00:51 Early Research and Challenges 05:04 Quality Control and Safety Concerns 09:58 Understanding Cannabis and Its Components 19:41 The Endocannabinoid System 23:01 CBD vs. THC: Effects and Applications 31:52 Current Research and Future Directions 40:00 Conclusion and Final Thoughts Get to know Dr. Narda Robinson: https://www.dogcancer.com/people/narda-g-robinson-do-dvm-ms-faama/ For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/ Learn more about your ad choices. Visit megaphone.fm/adchoices
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    42 m
  • What Is CBD vs. THC vs. Cannabis vs. Marijuana? Terms Explained! | Kate Basedow #281

    What Is CBD vs. THC vs. Cannabis vs. Marijuana? Terms Explained! | Kate Basedow #281
    Apr 14 2025
    If you’re looking at using THC and/or CBD with your dog, the choices can be confusing. Is CBD from hemp the same as from marijuana? Do you want full spectrum? Is THC the same as CBD? What’s cannabis, exactly??? Licensed veterinary technician and science writer Kate Basedow joins us to go over the key terms you’ll hear when it comes to CBD. In addition to safety, she explains why a Certificates of Analysis (COA) for quality assurance in CBD products for dogs might be important … and ventures into the endocannabinoid system's role in animals. This episode does not address the legal issues or medical benefits of the plant … but instead provides clarity so you can have an informed conversation with your veterinarian. Your Voice Matters! If you have a question for our team, or if you want to share your own hopeful dog cancer story, we want to hear from you! Go to https://www.dogcancer.com/ask to submit your question or story, or call our Listener Line at +1 808-868-3200 to leave a question. Related Links: Our CBD article: https://www.dogcancer.com/articles/supplements/cbd-for-dogs-with-cancer/ Check out our knowledgebase of supplements! https://www.dogcancer.com/supplements/ Chapters: 00:00 Introduction 00:21 Understanding Cannabis Terminology 01:04 Legalities and Availability of CBD and THC 02:15 Basic Cannabis Terms and Definitions 03:51 Cannabinoids and Their Effects 05:42 CBD vs. THC: Safety and Effects 07:22 Marijuana vs. Hemp 10:54 Endocannabinoid System Explained 14:25 Importance of Certificate of Analysis 18:49 Conclusion and Resources Get to know Kate Basedow: https://www.dogcancer.com/people/kate-basedow-lvt/ For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/ Learn more about your ad choices. Visit megaphone.fm/adchoices
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    27 m
  • Chinese Herbs & More: Integrative Vet Gives Supplement Advice | Dr. Jessica Tartof #280

    Chinese Herbs & More: Integrative Vet Gives Supplement Advice | Dr. Jessica Tartof #280
    Mar 31 2025
    Dr. Jessica Tartof explores the benefits of Chinese herbs, vitamin A, vitamin D, and various mushrooms like turkey tail and Myco-Forte. Dr. Tartof explains how testing guides her recommendations and why trusted supplement brands are essential. Tune in to learn how these supplements can help your dog fight cancer! Key Takeaways: Chinese Herbs: A customizable approach depending on your dog’s condition. Vitamins: Testing is critical before using vitamin D; vitamin A is used at safe levels. Mushrooms: Myco-Forte and turkey tail mushrooms are trusted staples in cancer care. Always consult your veterinarian before starting any supplements! Your Voice Matters! If you have a question for our team, or if you want to share your own hopeful dog cancer story, we want to hear from you! Go to https://www.dogcancer.com/ask to submit your question or story, or call our Listener Line at +1 808-868-3200 to leave a question. Related Videos: https://www.youtube.com/watch?v=9czPvOSrfoU https://www.youtube.com/watch?v=3kYLIbs1cFE Related Links: Check out our knowledgebase of supplements! https://www.dogcancer.com/supplements/ Chapters: 00:00 Introduction 00:30 - Listener Question: Supplements for Dog Cancer 00:45 - Dr. Tartoff’s Go-To Supplements: Chinese Herbs 01:15 - Synergistic Effects of Curcumin in Chinese Formulas 01:45 - Testing Vitamin D Levels Before Supplementing 02:15 - Safe Use of Vitamin A in Dogs 02:30 - The Role of Myco-Forte and Turkey Tail Mushrooms 03:00 - Adjusting Supplement Protocols Based on Testing 03:30 - Trusted Brands for Dog Cancer Supplements 04:00 - Closing Thoughts and Resources at DogCancer.com 04:15 - Disclaimer and Podcast Credits Get to know Dr. Jessica Tartof: https://www.dogcancer.com/people/jessica-tartof-dvm-gdipvchmcivt-cva-cvsmt/ For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/ Learn more about your ad choices. Visit megaphone.fm/adchoices
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    7 m