Bug Wars II: Time vs. Concentration — How Dosing Kills (or Fails) Podcast Por  arte de portada

Bug Wars II: Time vs. Concentration — How Dosing Kills (or Fails)

Bug Wars II: Time vs. Concentration — How Dosing Kills (or Fails)

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The drug was right. The culture said susceptible.
But the patient didn’t improve.

In this episode, we reveal the real reason antimicrobial therapy fails:
You didn’t match the drug’s kill style to the dosing strategy.

🔍 Learn:

  • The difference between time-dependent and concentration-dependent killing
  • Key PK/PD metrics like Time > MIC, Cmax/MIC, and AUC/MIC
  • Why some antibiotics demand frequent small doses while others want big hits
  • How drug class, site of infection, and patient physiology change your strategy
  • Common pitfalls that lead to treatment failure or resistance

🎯 Includes a board-style question and flashcard-style recap.

🎧 Built for surgical residents.
Feedback or requests? Carl Damiani (cd@simini.com)

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