In this episode of AI at Work, I sit down with Juan Orlandini, CTO North America at Insight, to unpack the often-overlooked side of AI adoption: regulation, data strategy, and governance. While much of the recent conversation around AI has focused on speed, productivity, and experimentation, Juan brings the discussion back to fundamentals. Before you scale that shiny new AI tool across your business, have you classified your data? Have you considered your compliance obligations? And do you understand the different responsibilities that come with being an AI creator, adapter, or consumer?

Juan walks us through Insight’s perspective on the current state of enterprise AI, including how they’ve used their own internal tools like InsightGPT to stress test both opportunities and risks. We discuss why internal use cases are often the best place to start, and how leaders can avoid repeating the mistakes of past tech waves, like the race to cloud or mobile apps without a clear strategy.

We also explore the patchwork of US regulations, with California leading the way, and compare this to the EU’s more prescriptive approach. Juan explains how these emerging policies are shaping real business decisions right now, and what business leaders can do to stay ahead. Throughout our chat, his advice is grounded and practical, offering a steady counterpoint to the noise and hype.

Whether deep in deployment or just starting to explore how AI fits into your business, Juan's insights offer a roadmap to thinking bigger while avoiding costly missteps. How do you keep your organization agile enough to adapt, but stable enough to deliver? And what does it really take to treat AI as an enterprise tool rather than a passing trend?

Tune in to hear Juan’s advice on managing risk, reimagining processes, and building a culture that is ready for what comes next.

What if AI could help us discover new medicines faster, more accurately, and with greater impact for patients?

In this episode of AI at Work, I speak with Dr. Chris Austin, Head of Research Technologies at GSK, to explore how artificial intelligence is changing the way new treatments are developed. Chris brings a unique perspective shaped by decades of experience across academia, biotech, government, and now big pharma. His mission at GSK is clear: to bring science, technology, and talent together to radically improve human health.

We unpack how AI, combined with massive clinical and genetic datasets, is enabling GSK to target disease with unprecedented precision. From identifying the right molecular pathways to simulating clinical trials using digital twins, Chris walks us through how technology is helping reduce development timelines and increase the chances of success. He shares powerful examples including a promising asthma treatment that moved from first-in-human testing to Phase 3 trials across four diseases in record time.

We also explore how GSK uses AI to improve patient selection in clinical trials, design oligonucleotide-based therapies for hard-to-treat conditions like hepatitis B, and incorporate generative AI into everything from drug design to safety prediction. According to Chris, the key isn't just having better algorithms. It's about generating the right data, at scale, to make those algorithms meaningful.

If you're curious about how AI is being applied to some of the most complex problems in healthcare, this episode offers a rare inside look. Chris also reflects on his journey from medicine to data science, and why this is the most exciting time he’s seen in drug development.

How do you transform a century-old creative institution into a future-ready force without losing sight of its roots?

In this episode of AI at Work, we spotlight Dr. Joyce Brown, President of the Fashion Institute of Technology (FIT), who has spent 26 years leading a quiet revolution in fashion education. As the first woman and first African American to hold the role, Dr. Brown has reimagined what it means to prepare students for creative careers in a digital world.

She shares how, when she took the helm in 1998, FIT was operating with outdated systems and a siloed approach to education. Through strategic planning, bold hiring decisions, and a commitment to change, she reshaped FIT into a collaborative, interdisciplinary, and forward-looking institution.

Under her leadership, FIT quadrupled its use of technology in teaching and launched the DTech Lab, a hands-on innovation hub where students work directly with brands like Netflix, Adidas, Girl Scouts, and Tommy Hilfiger to solve real challenges using emerging tech like AI and advanced materials.

This episode also explores how FIT is fostering a new wave of sustainable design. Students are using kombucha, mycelium, and pineapple fibers to rethink fashion from the ground up, while also cultivating a natural dye garden on campus. We unpack how the school integrates innovation, science, and sustainability without losing the soul of design.

Dr. Brown reflects on how FIT has responded to social and global shifts, from the pandemic to social justice movements, and how students are using creative work to make sense of the world. Her insights offer a compelling look at what education can achieve when it embraces experimentation, diverse voices, and emerging technologies.

Whether you're in fashion, tech, education, or simply interested in how institutions evolve, this conversation offers a masterclass in visionary leadership and what it takes to truly modernize without losing meaning.

How are you preparing your team or organization for a future shaped by creativity, technology, and purpose? Join the discussion.