Tessa Russo is the mother of two young children and the wife of a renowned pediatric surgeon. Despite her own mother's warnings, Tessa has recently given up her career to focus on her family and the pursuit of domestic happiness. From the outside, she seems destined to live a charmed life. Valerie Anderson is an attorney and single mother to six-year-old Charlie - a boy who has never known his father.

Ellen and Andy's first year of marriage doesn't just seem perfect, it is perfect. There is no question how deep their devotion is, and how naturally they bring out the best in each other. But one fateful afternoon, Ellen runs into Leo for the first time in eight years. Leo, the one who brought out the worst in her. Leo, the one who left her heartbroken with no explanation. Leo, the one she could never quite forget. When his reappearance ignites long-dormant emotions, Ellen begins to question whether the life she's living is the one she's meant to live.

First comes love. Then comes marriage. Then comes . . . a baby carriage? Isn't that what all women want? Not so for Claudia Parr. And just as she gives up on finding a man who feels the same way, she meets warm, wonderful Ben. Things seem too good to be true when they fall in love and agree to buck tradition with a satisfying, child-free marriage. Then the unexpected occurs: one of them has a change of heart. One of them wants children after all.

Nina Browning is living the good life after marrying into Nashville's elite. More recently, her husband made a fortune selling his tech business, and their adored son has been accepted to Princeton. Yet sometimes the middle-class small-town girl in Nina wonders if she's strayed from the person she once was. Tom Volpe is a single dad working multiple jobs while struggling to raise his headstrong daughter, Lyla. His road has been lonely, long, and hard, but he finally starts to relax after Lyla earns a scholarship to Windsor Academy, Nashville's most prestigious private school.

Growing up, Josie and Meredith Garland shared a loving, if sometimes contentious, relationship. Josie was impulsive, spirited, and outgoing, Meredith hardworking, thoughtful, and reserved. When tragedy strikes, their delicate bond splinters.

The Kingsley family is American royalty, beloved for their military heroics, political service, and unmatched elegance. In 1967, after Joseph S. Kingsley, Jr. is killed in a tragic accident, his charismatic son inherits the weight of that legacy. But Joe III is a free spirit—and a little bit reckless. Despite his best intentions, he has trouble meeting the expectations of a nation, as well as those of his exacting mother, Dottie.

Hollis Shaw, creator of the popular food blog, Hungry with Hollis, is shocked when her heart surgeon husband, Matthew, is killed in a one-car accident on a snowy morning. The cracks in Hollis’s perfect life—her strained marriage and her complicated relationship with her daughter, Caroline—grow deeper. So when Hollis hears about something called a “Five-Star Weekend”—one woman organizes a trip for her best friend from each phase of her life: her teenage years, her twenties, her thirties, and midlife—she decides to host her own Five-Star Weekend on Nantucket.

Lily hasn’t always had it easy, but that’s never stopped her from working hard for the life she wants. She’s come a long way from the small town where she grew up—she graduated from college, moved to Boston, and started her own business. And when she feels a spark with a gorgeous neurosurgeon named Ryle Kincaid, everything in Lily’s life seems too good to be true.

Harriet and Wyn have been the perfect couple since they met in college—they go together like salt and pepper, honey and tea, lobster and rolls. Except, now—for reasons they’re still not discussing—they don’t. They broke up five months ago. And still haven’t told their best friends.

Fallon meets Ben, an aspiring novelist, the day before her scheduled cross-country move. Their untimely attraction leads them to spend Fallon's last day in LA together, and her eventful life becomes the creative inspiration Ben has always sought for his novel. Over time and amidst the various relationships and tribulations of their own separate lives, they continue to meet on the same date every year.

Can you ever really know if love is true? And if it is, should you stop at anything to get it? Two decades ago, Erin Edwards was sure she’d already found the love of her life: Nate Lawson. Her first love. The one with whom she shared everything--dreams of the future, of children, plans for forever. The one she thought she would spend the rest of her life with. Until one terrible night when Erin made a mistake Nate could not forgive and left her to mourn the relationship she could never forget or get over.

Twenty years ago, Allie Denty was the pretty one and her best friend Olivia Pelham was the smart one. Throughout high school, they were inseparable...until a vicious rumor about Olivia - a rumor too close to the truth - ended their friendship. Now, on the eve of their 20th high school reunion, Allie, a temp worker, finds herself suddenly single, a little chubby, and feeling old.

Nisha Cantor lives the globetrotting life of the seriously wealthy, until her husband announces a divorce and cuts her off. Nisha is determined to hang onto her glamorous life. But in the meantime, she must scramble to cope--she doesn’t even have the shoes she was, until a moment ago, standing in. That’s because Sam Kemp—in the bleakest point of her life—has accidentally taken Nisha’s gym bag. But Sam hardly has time to worry about a lost gym bag—she’s struggling to keep herself and her family afloat.

Daisy Shoemaker can’t sleep. With a thriving cooking business, full schedule of volunteer work, and a beautiful home in the Philadelphia suburbs, she should be content. But her teenage daughter can be a handful, her husband can be distant, her work can feel trivial, and she has lots of acquaintances, but no real friends. Still, Daisy knows she’s got it good. So why is she up all night?

They say you can never go home again, and for Persephone Fraser, ever since she made the biggest mistake of her life a decade ago, that has felt too true. Instead of glittering summers on the lakeshore of her childhood, she spends them in a stylish apartment in the city, going out with friends, and keeping everyone a safe distance from her heart. Until she receives the call that sends her racing back to Barry’s Bay and into the orbit of Sam Florek—the man she never thought she’d have to live without.