The summer that Nixon resigns, six teenagers at a summer camp for the arts become inseparable. Decades later the bond remains powerful, but so much else has changed. In The Interestings, Wolitzer follows these characters from the height of youth through middle age, as their talents, fortunes, and degrees of satisfaction diverge. The kind of creativity that is rewarded at age 15 is not always enough to propel someone through life at age 30; not everyone can sustain, in adulthood, what seemed so special in adolescence.

The moment Joan Castleman decides to leave her husband, they are 35,000 feet above the ocean on a flight to Helsinki. Joan's husband, Joseph, is one of America's preeminent novelists, about to receive a prestigious international award, and Joan, who has spent 40 years subjugating her own literary talents to fan the flames of his career, has finally decided to stop.

In the spring of 2020, Lara’s three daughters return to the family's orchard in Northern Michigan. While picking cherries, they beg their mother to tell them the story of Peter Duke, a famous actor with whom she shared both a stage and a romance years before at a theater company called Tom Lake. As Lara recalls the past, her daughters examine their own lives and relationship with their mother, and are forced to reconsider the world and everything they thought they knew.

When Jack and Elizabeth meet as college students in the gritty '90s Chicago art scene, the two quickly join forces and hold on tight, each eager to claim a place in the thriving underground scene with an appreciative kindred spirit. Fast-forward twenty years to suburban married life, and alongside the challenges of parenting, they encounter the often-baffling pursuits of health and happiness from polyamorous would-be suitors to home-renovation hysteria.

William Waters grew up in a house silenced by tragedy, where his parents could hardly bear to look at him, much less love him—so when he meets the spirited and ambitious Julia Padavano in his freshman year of college, it’s as if the world has lit up around him. With Julia comes her family, as she and her three sisters are inseparable: Sylvie, the family’s dreamer, is happiest with her nose in a book; Cecelia is a free-spirited artist; and Emeline patiently takes care of them all.

Sam and Sadie—two college friends, often in love, but never lovers—become creative partners in a dazzling and intricately imagined world of video game design, where success brings them fame, joy, tragedy, duplicity, and, ultimately, a kind of immortality. It is a love story, but not one you have heard before.

Chemist Elizabeth Zott is not your average woman. In fact, Elizabeth Zott would be the first to point out that there is no such thing as an average woman. But it’s the early 1960s and her all-male team at Hastings Research Institute takes a very unscientific view of equality. Except for one: Calvin Evans; the lonely, brilliant, Nobel–prize nominated grudge-holder who falls in love with—of all things—her mind. True chemistry results.

Ranita Atwater is “getting short.” She is almost done with her four-year sentence for opiate possession at Oak Hills Correctional Center. Three years sober, she is determined to stay clean and regain custody of her two children. Ranita is regaining her freedom, but she’s leaving behind her lover Maxine, who has inspired her to imagine herself and the world differently.

Jivan is a Muslim girl from the slums, determined to move up in life, who is accused of executing a terrorist attack on a train because of a careless comment on Facebook. PT Sir is an opportunistic gym teacher who hitches his aspirations to a right-wing political party and finds that his own ascent becomes linked to Jivan's fall. Lovely—an irresistible outcast whose exuberant voice and dreams of glory fill the novel with warmth and hope and humor—has the alibi that can set Jivan free, but it will cost her everything she holds dear.

Our narrator should be happy, shouldn't she? She's young, thin, pretty, a recent Columbia graduate; she works an easy job at a hip art gallery and lives in an apartment on the Upper East Side of Manhattan paid for, like the rest of her needs, by her inheritance. But there is a dark and vacuous hole in her heart, and it isn't just the loss of her parents, or the way her Wall Street boyfriend treats her, or her sadomasochistic relationship with her best friend, Reva. It's the year 2000 in a city aglitter with wealth and possibility; what could be so terribly wrong?

Ba dies in the night; Ma is already gone. Newly orphaned children of immigrants, Lucy and Sam are suddenly alone in a land that refutes their existence. Fleeing the threats of their Western mining town, they set off to bury their father in the only way that will set them free from their past. Along the way, they encounter giant buffalo bones, tiger paw prints, and the specters of a ravaged landscape as well as family secrets, sibling rivalry, and glimpses of a different kind of future.

In 1985, Yale Tishman, the development director for an art gallery in Chicago, is about to pull off an amazing coup, bringing in an extraordinary collection of 1920s paintings as a gift to the gallery. Yet as his career begins to flourish, the carnage of the AIDS epidemic grows around him. One by one, his friends are dying and after his friend Nico's funeral, the virus circles closer and closer to Yale himself. Soon the only person he has left is Fiona, Nico's little sister.

Theo Byrne is a promising young astrobiologist who has found a way to search for life on other planets dozens of light years away. He is also the widowed father of a most unusual nine-year-old. His son, Robin, is funny, loving, and filled with plans. He thinks and feels deeply, adores animals, and can spend hours painting elaborate pictures. He is also on the verge of being expelled from third grade for smashing his friend's face with a metal thermos.

When Astrid Strick witnesses a school bus accident in the center of town, it jostles loose a repressed memory from her young parenting days decades earlier. Suddenly, Astrid realizes she was not quite the parent she thought she'd been to her three, now-grown children. But to what consequence?

The Latecomer follows the story of the wealthy, New York City-based Oppenheimer family, from the first meeting of parents Salo and Johanna, under tragic circumstances, to their triplets born during the early days of IVF. As children, the three siblings—Harrison, Lewyn, and Sally—feel no strong familial bond and cannot wait to go their separate ways, even as their father becomes more distanced and their mother more desperate. When the triplets leave for college, Johanna, faced with being truly alone, makes the decision to have a fourth child.